libera/##covid-19/ Saturday, 2020-04-25

CoronaBot04/r/coronavirus: Native Americans being left out of US coronavirus data and labelled as 'other' (10015 votes) | https://redd.it/g76gft00:00
mefistofeles↑ heh00:00
Sinovacantibody do not last long00:01
mefistofelesSinovac: we still don't know, it can happen that they don't last too long, indeed00:01
LjLpfft Guardian is getting a TAD misleading with its headlines too. i understand they don't love the US adminsitration, neither do i, but...00:01
LjLthe article doesn't say they are "left out" of the data00:01
mefistofeleswas that Guardian?00:01
LjLyeah00:01
mefistofelesGuardian is getting worse and worse00:02
nixonixLjL: did you get information on italian md's, share of males?00:02
LjLyeah, i saw some article earlier (that i didn't repost here) that was a bit of stretch, but i forget now00:02
LjLnixonix, oh yeah i forgot you had highlighted me about that... but no, not really00:02
LjLi'll have another go at searching00:02
nixonixthat study i linked above had 90%. so maybe that 95% claim was true then00:03
Sinovacactually you don't need antibody to get immunity 00:03
mefistofelesSinovac: btw, that's why antibodies studies will continue for a year00:03
mefistofelesSinovac: that's still not known00:04
Sinovacantibody is only issued if covid is detected 00:04
mefistofelesSinovac: what?00:04
Sinovacby the body00:04
Sinovacyes taht00:04
Sinovacthat00:04
NoImNotNineVoltLjL: i'm only personally familiar with the hopkins dataset, sorry.00:05
Sinovacactually you don't need antibody to get immunity 00:05
mefistofelesah yes, there are even cases of the younger people not showing any antibodies after having positively tested for covid00:05
ecksall the covid irc channels should be renamed ##babbysfirstimmunology00:05
NoImNotNineVolt^^00:05
mefistofelesso this suggest other mechanisms, but still nothing conclusive00:05
Sinovacantibody shows you got covid recently00:05
ragerantibody shows that your body created antibodies for covid-1900:06
ragerwhich is correlated with having cleared illness 00:06
NoImNotNineVoltsars-cov-2 is the virus. covid-19 is the respiratory illness it can cause.00:06
LjLand they're likely to lasts at least for some months, based on what we know on other coronaviruses00:06
ragerokay, okay00:06
LjLclearly we can't predict the future with this one00:06
ragerfor sars-cov-2 or 2019-ncove00:07
rageror whatever00:07
nbNoImNotNineVolt, hmm. so is it possible someone could get sars-cov-2 and only be a carrier and never get covid-19 i guess?00:07
ragerwhen there's a 1:1 mapping on virus and diseases, the words are interchangeable, NoImNotNineVolt 00:07
LjLnb, well what's the technical difference between that, and someone who has it asymptomatically?00:07
NoImNotNineVoltnb: it's estimated that 60% of sars-cov-2 carriers never develop any symptoms at all, let alone covid-19.00:07
mefistofelesLjL: still, many things behave like other things we know, it's not as if anything is possible and we are left out in the dark00:07
ragerat what point are you an asymptomatic carrier vs having been exposed an not gotten ill?00:08
NoImNotNineVoltrager: i'm okay with being called pedantic, but i really prefer if we're precise with our words around complex subjects.00:08
NoImNotNineVoltrager: i don't see a difference.00:08
LjLmefistofeles, well, that's my point, we can mostly assume that they last for some months, which in reference to the studies in NY and Germany, to me, shows that if 15% of the population have antibodies, it is unlikely that MORE than 15% had COVID, nevermind a majority00:08
LjLit isn't an absolute certainty but we can assume it for now00:08
ecksmaybe the antibodies were practicing social distancing and thus were not part of the blood drawn for the test00:09
ragerNoImNotNineVolt: maybe there's a non-linearity somewhere in the relationship between viral load and infectiousness00:09
ragertransmissivity, whatever00:10
mefistofelesLjL: it's a bit tricky00:10
mefistofelesLjL: there's a significant amount of people not showing antibodies, but let me get the exact numbers00:10
ragerif there are some threshold conditions that make cases distinct, it's interesting, right?00:10
mefistofelesand let me rephrase that00:10
LjLmefistofeles, ah, yes, that part should be considered00:11
ragermefistofeles: 30% is the number i saw bandied about00:11
NoImNotNineVoltrager: there seems to be a clear discrepancy between patients regarding the relationship between viral load and presentation of symptoms.00:11
LjLrager, that was within a certain age range though, lower in general (6%?)00:11
ragerbut that was in the 20-50 age range in particular00:11
mefistofelesLjL: there's a significant amount of people not developing detectable loads of antibodies after being infected by covid and having recovered00:11
NoImNotNineVoltnonlinearity aside :P00:11
mefistofelesthere :P00:11
LjLmefistofeles, make my point more... we have no reason to think the current antibody tests are missing people who have *already lost* antibodies despite initially having them. that said, yes, they should still be "corrected" for the amount of people who simply don't get antibodies00:11
ragerNoImNotNineVolt: definitely - people seem to get worse symptoms from a worse initial exposure (and possibly a faster ramp-up of viral load?)00:12
ragerdoes anybody here actually immune system?00:12
NoImNotNineVoltwe don't have sufficient data regarding persistence of antibodies or persistence of immuninity.00:12
ragerlike... does concentration of antibodies in serum correlate with the body's capacity to make said antibodies?00:13
berndjrager, i wondered about that ramp-up00:13
berndjwhat's the eclipse period anyway?00:13
ragerI don't know these kinds of things.00:13
NoImNotNineVoltto clarify, i don't immunity. i'm a bioinformatics student.00:14
NoImNotNineVolti doubt there's any clinicians on irc at a time like this, though :P00:14
mefistofelesLjL: ah right, yes00:16
mefistofelesI've read that up to 30% in an study didn't show a high antibody count, some didn't show any antibodies at all00:16
mefistofeleshow low? not sure, and whether antibodies test can detect those, ni idea00:16
mefistofelesno*00:17
friedbatyes, several studies show low titers in a good amount of recovered patients00:17
ragermight be lucky enough to get grad students in that kinda stuff00:18
LjLmefistofeles, again though i think the 30% was just in young patients, rager said in the 20-50 range00:22
LjLin total it might have been 6%00:22
LjLi mean among all people00:23
LjLstill relevant, of course00:23
mefistofelesLjL: that 30% is for all, but yes, they are the younger patients00:24
ubLIXspeaking of the Guardian being somewhat anti-American, how about the Associated Press view of the US right now: https://apnews.com/1283d176484e133f31080227bb15c5d100:24
LjLmefistofeles, oh, 30% in total? i have to reread it then, as i wouldn't know what the 6% number was then00:25
mefistofelesLjL: well, it literally says "30% of the entire cohort"00:25
mefistofelesso I assume it means all of them00:25
mefistofelesLjL: https://blogs.sciencemag.org/pipeline/archives/2020/04/08/covid-19-antibody-update-for-april-8 fwiw00:25
LjLmefistofeles, if you're already re-reading it do you have linkie handy?00:25
LjLthanks00:25
ragerthese people have some numbers for seroconversion: https://www.assaygenie.com/antibody-seroconversion-response-in-covid1900:26
mefistofelesrager: interesting00:30
mefistofelesmaybe the paper cited in the blog I posted didn't waited enough? they say 10-15 days00:31
ragerthey're only seeing 93.1% seroconversion rates00:31
mefistofeleswhile that other says up to 39days, and that 50% was achieved in day 1100:31
ragerwhich is way better than 70%, at least00:31
mefistofelesrager: what does that mean?00:31
mefistofelesthe seroconveration rate00:32
mefistofelesconversion00:32
mefistofelesoh man, I really need to get some rest xD x00:32
LjLmefistofeles, not entirely sure which hat i got 6% from. i guess it might be the amount of patients with NO measurable antibodies but i'm not even sure00:32
mefistofelesLjL: yes00:32
mefistofeles10 out of 17500:32
ragerthat's the hit-rate for antibodies in testing00:32
mefistofelesrager: like accuracy?00:33
LjLoh okay, at least i can't read and i can't remember where i read things, but i'm not making them up completely00:33
ragerso 6.9% of participants in that study did not exhibit either igm or igg antibodies over the course of the experiment00:33
mefistofelesrager: ah ok, so similar numbers00:33
mefistofelesinteresting00:33
mefistofelesthey also have a very similar sample size00:33
LjLwhich means... only about 1% or so of people who register ANY antibodies at ANY point during the disease, subsequently lose them?00:33
mefistofelesonly time varies00:33
LjLor is that too much of a leap00:33
mefistofelesLjL: wait? how?00:34
ragerthat's a leap00:34
ragersince no study follows survivors for that long00:34
ragerbecause it hasn't been that long00:34
LjLokay, yeah, i expressed myself incorrectly again00:34
LjLwe don't know if antibodies last forever, or even for long00:35
BrainstormNew from The Guardian at 22:30 UTC: Anzac Day: Australia coronavirus update latest: Anzac Day dawn services marked in isolation – live news → https://is.gd/6NmdeZ00:35
LjLbut, 10/175 is about 5.7%, but unless i imsunderstood, you're saying 6.9% did not exhibit any antibodies ever00:35
mefistofelesLjL: but where does that 1% come from?00:35
LjLso, 1.2% exhibited them at some point, but then they didn't...?00:35
mefistofelesLjL: those are two different studies00:35
mefistofelesnow I see the 1% :P00:36
LjLoh00:36
LjLokay i'm sorry, i don't actively try to fail to read things, it just happens00:36
mefistofelesso, it's around 6.3% xD00:37
rageruhh... sorry for long link00:37
ragerhttps://www.mdlinx.com/journal-summaries/viral-infections-severe-acute-respiratory-syndrome/2020/03/31/7635124/ gets there eventually00:38
BrainstormUpdates for US: +6755 cases (now 922293), +369 deaths (now 52061) since an hour ago — Massachusetts, US: +4946 cases (now 50969), +196 deaths (now 2556) since a day ago — Canada: +1304 cases (now 44856) since an hour ago00:39
ragerso past studies could have not followed people long enough00:39
ragerto quote: "The cumulative seroconversion curve showed that the rate for Ab and IgM reached 100% around 1-month after onset"00:39
ragermethodology:00:41
rager"A total of 173 patients with SARS-CoV-2 infection were enrolled. Their serial plasma samples (n=535) collected during the hospitalization were tested for total antibodies (Ab), IgM and IgG against SARS-CoV-2. The dynamics of antibodies with the disease progress was analyzed.00:41
tinwhiskersThanks rager. That's interesting00:41
mefistofeleshttps://www.medrxiv.org/content/10.1101/2020.03.30.20047365v2 the other one is this, fwiw00:41
ragerbut "total antibodies" sounds like "we couldn't find knon sars-cov-2 specific antibodies"00:42
BrainstormNew from The Atlantic at 22:38 UTC: Why It’s Important Not to Drink Bleach: One of the few definitive things that can be said about reopening the U.S. economy is that any plan will involve aggressive hygiene and sanitizing. Because the coronavirus can live on surfaces for several days, it seems to spread more often via something you touched than [... want %more?] → https://is.gd/Or1j6E00:42
ytlyv8https://www.mdlinx.com/internal-medicine/top-medical-news/article/2020/03/30/763511700:42
mefistofelesLOL00:42
mefistofeles"why it's important not to drink bleach"00:42
pynabest possible future00:42
mefistofelesfucking trump xD00:42
ytlyv8vote for trumpp  you will get a cure lol00:44
bin_bashhttps://i.imgur.com/xTCg9Cn.jpg00:44
mefistofeleshaha00:44
tinwhiskerslol00:45
CoronaBot04/r/coronavirus: Miami goes seven weeks without a homicide for first time since 1957 (10078 votes) | https://redd.it/g7egky00:48
mefistofelesoh that's right, crime rates should be really low in many places00:49
BrainstormNew from The Guardian at 22:39 UTC: Anzac Day: Australia coronavirus update latest: Anzac Day dawn services marked in isolation – live news → https://is.gd/6NmdeZ00:49
livebrainhere someone tried to rob an atm machine by drinving into it00:50
livebrainand they engaged the police 00:50
livebrainone criminal was shot00:50
ragergonna have a lot less "stochastic crime" as the pressure of the operating fluid is far lower00:51
ragerby driving into them?00:51
pynahuh, pretty good https://developer.aylien.com/text-api-demo?run=1&input=https%3A%2F%2Fwww.theatlantic.com%2Fhealth%2Farchive%2F2020%2F04%2Ftrump-bleach-coronavirus%2F610690%2F&language=en&url=https%3A%2F%2Fwww.theatlantic.com%2Fhealth%2Farchive%2F2020%2F04%2Ftrump-bleach-coronavirus%2F610690%2F&&tab=concepts00:51
Sinovaci hope life never goes back to normal 00:51
Sinovacits so peaceful right now00:51
livebrainwell i wouldnt mind a vaccine00:52
ytlyv8kill the weaklings00:52
livebraini have to go out for work00:52
livebrainand i freak out everytime i ear someone coughing00:52
livebrainand everytime i cough i think im gone00:53
ytlyv8licks   live00:53
Sinovacuse perfume 00:53
Sinovaclots of it00:53
livebrainthat will attrack alot of women :(00:53
livebraini cant00:53
Sinovackeeps people away 00:53
livebrainsocial distanting00:53
Sinovacand kill virus00:54
Sinovacits totality legal form of chemicalwarfare00:55
BrainstormNew from Reddit (test)* at 22:52 UTC: nCoV: Bored At Home | Tips For What To Do When You’re Bored in Quarantine (3 BENEFITS!) | 24APR20 → https://is.gd/gHQs2a00:56
friedbat21 minute press briefing so i guess they figured out that making dumb comments about disinfectants isn't the best thing to do00:56
Sinovacmight attract bees thou00:57
Sinovacjust dumb?00:57
tinwhiskerswow. that must be about a record, friedbat00:58
ytlyv8coat all infected areas with honey00:58
Sinovacif i made such claims in here i would get kicked00:58
hirogenI've realised that since covid started00:59
friedbattinwhiskers: i think so, 21 minutes is very short. they're usually hours.00:59
hirogenthere's this bird which I've never heard before at night make strange sounds00:59
hirogennever ever00:59
hirogenso even as a kid in the 80's in a green location it must have never come so close to civilisation dunno why though, maybe everyones feeding birds who know or the lack of pollution is my guess01:00
Sinovaccoroninghale?01:00
Sinovacits just like the legend movie01:01
Sinovacwith will smith01:01
LjLhirogen, not sure, but you're not the first report of this kind that i hear01:01
LjLanimals are probably taking some of their spaces back, to some limited extent01:02
mefistofelesyes, that has been seen and quantified iirc01:02
tinwhiskersalso people taking time to smell the roses, less road noise, less pollution, etc01:02
mefistofelestinwhiskers: what? how does that roses thing is pertinent? haha01:03
tinwhiskersheh01:03
BrainstormNew from The Lancet at 00:00 UTC: [Perspectives] Modelling can only tell us so much: politics explains the rest: I've been self-isolating with my family because we developed fevers. Whether this is any illness or coronavirus disease 2019 (COVID-19) is hard to say given the UK Government's position on community testing. How this infection started, how [... want %more?] → https://is.gd/AJLM2y01:03
mefistofelestoday I got my "terrorist" mask :P01:04
tinwhiskers"time to smell the roses" means taking time to be more aware of your surroundings01:04
Sinovactime for a bat invasion movie01:04
tinwhiskersmefistofeles: photos?01:04
LjLtinwhiskers, i understand, i'm just not sure the cops will01:04
tinwhiskersLjL: :-)01:05
mefistofelestinwhiskers: maybe monday, we will be raiding a supermarket with some friends, all wearing these masks01:05
LjLlucky enough though we have some roses in the yard01:05
tinwhiskersmefistofeles: home made?01:05
LjLi think i am allowed to linger in our yard for a bit01:05
mefistofelestinwhiskers: no, amazon01:05
tinwhiskerslink?01:05
LjLnot in the building halls, but at least the yard01:05
ytlyv8you have your mask report to your new job bank guard01:06
mefistofelestinwhiskers: I didn't buy them, but let me see if there's some name of brand or something01:06
tinwhiskersoh. ok01:06
mefistofelesit just says, face mask, made in china XD01:06
LjLwe buy too much bottled water... i wanted to buy one of these filter jugs but it won't fit in the fridge, and from what i understand it's not exceedingly safe to keep it unrefrigerated01:06
Sinovacroses don't smell like much01:07
tinwhiskerserm. yeah, it's an idiom or some such, not intended literally.01:07
friedbati don't know about you all, but i've noticed more vibrant wildlife 01:08
friedbatsince this worldwide quarantine01:08
NoImNotNineVoltLjL: i've been keeping one unrefrigerated for years with no known adverse effects.01:08
friedbatwe're the virus01:08
NoImNotNineVoltit's just water.01:08
mefistofelestinwhiskers: http://i.ebayimg.com/images/i/221969287894-0-1/s-l1000.jpg similar to that one01:09
NoImNotNineVoltpeople have been storing water unrefrigerated since the invention of pottery, and they didn't even have the benefit of chlorine or carbon filters.01:09
LjLNoImNotNineVolt, how often do you change the cartridges? the thing is, tap water is chlorinated for safety... these jugs remove the chlorine, because that's like 75% of their point as people don't like the taste. but then you have water that's sitting there and *without* its usual disinfectant in it01:09
tinwhiskersmy water sits in a tank out in the sun, often for six mnonths. it's fine even with a bit of bat poop in it.01:09
LjLNoImNotNineVolt, people have also gotten all sorts of foodborne diseases, though01:09
tinwhiskersmefistofeles: ninja!01:09
NoImNotNineVoltfair enough.01:09
mefistofelestinwhiskers: yeah01:09
LjLi don't think just "people have done it for millennia" is a good enough reassurance :P01:10
NoImNotNineVolti mean, i haven't gotten dysentery once :P01:10
NoImNotNineVolti'm but an anecdote, but still.01:10
LjLtinwhiskers, maybe you'll be the first COVID-19 case on the island and it won't be even human-to-human. ain't that exciting?01:10
tinwhiskersheh01:10
tinwhiskersthere's all sorts of things that could grow in water sitting around, such as toxic algae, so it could go bad for sure.01:11
ytlyv8little bleach in the water your good01:11
NoImNotNineVolti don't think filtering chlorinated water some more before storing it in a clean receptacle is a significant risk to my health.01:11
tinwhiskersNoImNotNineVolt: no01:11
LjLytlyv8, if i'm using a jug to get rid of the chlorine i'll probably not be adding bleach back01:11
ytlyv8try moonshine01:11
mefistofelesLjL: better inject yourself with bleach01:12
LjLNoImNotNineVolt, probably not, but the cartridges in these things have already been known to harbor some bacteria, so my concern is it may have more bacteria than it does out of the tap, *and* no chlorine to keep them in check01:12
ytlyv8vinger for cleaning01:12
LjLmefistofeles, grabbing the needle01:12
Sinovacmoonshine kills covid 01:12
NoImNotNineVoltat least not any more of a risk than would otherwise be posed by tainting the purity of my precious bodily fluids with foreign substances01:12
tinwhiskersSinovac: that's the sort of comment that spreads confusion01:12
mefistofelesSinovac: yes, just stop the nonsense01:13
NoImNotNineVoltcovid is a respiratory disease and cannot be killed :P01:13
LjLNoImNotNineVolt, this time i'm almost not rolling my eye at your distinguishing between COVID-19 and SARS-CoV-201:13
LjLwhich, by the way, is annoyingly annoying to type01:13
NoImNotNineVoltncov works too.01:13
mefistofelesNoImNotNineVolt: if there are no human or living being to get a disease is it still a disease?01:13
mefistofelesphylosophical question01:14
mefistofeles;)01:14
NoImNotNineVoltmefistofeles: a good question, and the corrolary: is death an effective preventative treatment for this pandemic?01:14
mefistofelesNoImNotNineVolt: we need to start trials01:14
Sinovacpreventative no 01:14
Sinovacit might mitigate it01:15
NoImNotNineVoltno? r0>1 for dead people?01:15
mefistofelesheh01:15
mefistofelesanyways, nite o/01:15
tinwhiskersSinovac: no01:15
NoImNotNineVoltit's 5oclock somewhere, happy friday.01:16
friedbatwhat are the latest best estimates for R₀ given strong mitigation (stay at home, closed non-essential business, closed schools)?01:16
NoImNotNineVoltw/ error bars pls01:16
tinwhiskersSinovac: if you had enough alcohol in your system to have any effect whatsoever you'd be dead. That's exactly the sort of nonsense Trump was spreading and it does harm as it confuses people. Don't speculate on medical advice as if it's a fact01:17
Sinovacalcohol in your system?01:17
Nsvsonidopeople from USA, what we get in Europe about your country is that there are demonstrations against lock down, and calling all this a HOAX... please tell me that is not true and what we see is minioritary01:17
tinwhiskersmoonshine01:17
friedbati recall that initially they were discussing R₀ between 2 and 3, or therabouts01:18
friedbatand that was without mitigation01:18
Sinovaci mean your throat 01:18
Sinovacthe virus dies off01:18
friedbatdoes strong mitigation get us far below the threshhold 1.0?01:18
NoImNotNineVoltconsumption of alcohol is correlated with suppressed immune response.01:18
Nsvsonidohttps://twitter.com/C4Dispatches/status/1241803403619172359?s=2001:18
NoImNotNineVoltclinically effective concentrations of alcohol are fatal.01:18
Sinovacbefore infectin g you01:19
tinwhiskersSinovac: that's crazy. even russians don't drink 100% of the time. It's not going to do anything for the viruses that are already in you01:19
SinovacIt's not going to do anything for the viruses that are already in you01:19
tinwhiskersYou said "preventative no, it might mitigate". Don't say that sort of thing here. please.01:19
NoImNotNineVoltNsvsonido: it's true to various degrees.01:19
Sinovacthat waht i said01:19
NoImNotNineVoltNsvsonido: a very small minority of people are involved in protests.01:20
Sinovacmitigate?01:20
Sinovacdo i need a lawayer to chat in here?01:20
NoImNotNineVoltNsvsonido: a significantly larger minority of people are calling it a hoax.01:21
Sinovacwtf are you all stupid?01:21
friedbatnew sympoms added by u.s. cdc: chills, shaking with chills, sore throat, loss of taste, loss of smell01:21
NoImNotNineVoltSinovac: it doesn't mitigate it. it worsens it.01:21
LjLfriedbat, "far below?" i don't know, Lombardy is still being sort of linear from what i can see01:21
LjLand the lockdown is as strong as it can get in Italiland01:21
NoImNotNineVoltSinovac: clinically effective concentrations of alcohol are fatal. lesser concentrations simply suppress immune response.01:21
Sinovacbefore infecting you01:22
friedbatwhen did lombardy lock down?01:22
LjLfriedbat, hard to say exactly... technically, March 8, but the flavor of lockdown changed a few time since01:22
NoImNotNineVoltSinovac: "before infecting you"?01:22
NoImNotNineVoltclinically effective concentrations of alcohol are fatal both before infection by ncov, during, and after.01:23
Nsvsonidoall the American people I see interviewed seem to suffer of this https://en.wikipedia.org/wiki/Cognitive_dissonance and they will die because of it01:23
SinovacNoImNotNineVolt im not even goin there so go chat with trunk on twiter01:23
NoImNotNineVoltsimilarly, lesser concentrations of alcohol simply suppress immune response, both before, during, and after ncov infection.01:23
NoImNotNineVoltSinovac: i don't know who trunk is nor do i have a twitter account. i was just responding to your statements here.01:24
Sinovacok if you get covid and die dont say i didnt told you so01:24
ytlyv8 50 says Sinovac  dead first01:25
tinwhiskersSinovac: again, you're pushing this alcohol thing as if you'd be foolish to ignore this advice. That's not acceptable here. It is not good advice.01:25
LjLSinovac, ytlyv8: neither of that is funny01:25
Sinovacits funny01:26
LjLokay, fair enough, you can decide for yourself whether it's funny. but i get to decide whether you can say it here, so i'm telling you, don't01:27
Sinovacyes sir01:28
Sinovacat least we got #covid-19 the real covid channel01:29
LjLokay, have fun there then01:30
NoImNotNineVoltso far, that channel is little more than a reddit integration bot and a handful of people spreading misinformation.01:30
LjLmentioning it once was more than enough, using it as a spam keyword every time i tell them not to do something is another matter01:31
ytlyv8anmd saying that when there gone is a waste of time01:32
tinwhiskerso.O01:32
NoImNotNineVoltSinovac: welcome back.01:33
LjLi clearly cannot type01:34
LjLytlyv8 also has basically only come here periodically to be annoying but only for brief enough period that they never got banned01:35
LjLideally they would all make their own channel somewhere with a name that doesn't clash with this one, but things are seldom ideal01:35
NoImNotNineVoltytlyv8 also left the channel immediately after sharing their observation.01:38
tinwhiskersyeah, strange rageComment01:38
NoImNotNineVoltmaking a statement like that immediately prior to parting the channel might be described as a waste of time.01:38
tinwhiskersheh01:38
LjLwell, they were also pointing out that it was a waste of time for me to state something about someone i had banned01:39
NoImNotNineVolti thought it was a pretty balanced exercise in moderation.01:39
NoImNotNineVoltthen again, it doesn't matter what i think.01:39
LjLbut i don't exactly feel that way since there's like 633 users, and probably about as many as 20 people here, who may care about what i say about banned people (or not, but potentially)01:39
NoImNotNineVoltirc channels are small fiefdoms.01:39
NoImNotNineVoltand you have the danish.01:39
pyna DOWN PERISCOPE01:41
LjLi believe... that was a silent torpedo launch?01:44
Urchinhttps://www.youtube.com/watch?v=8mtLigCACyQ01:51
LjL%title02:00
BrainstormLjL: From www.youtube.com: YouTube02:00
LjLhow useful, Brainstorm02:00
LjLMars confinement tips by the ESA02:00
LjLdon't thank me02:00
Urchinmight help someone02:01
Nsvsonidohttps://twitter.com/C4Dispatches/status/1241803403619172359?s=2002:09
tinwhiskers✓@C4Dispatches (Channel 4 Dispatches): “If you are irresponsible enough to think that you don’t mind if you get the flu, remember it’s not about you - it’s about everybody else.” Intensive care specialist Professor Hugh Montgomery explains why this coronavirus is different from the ordinary flu. https://t.co/h9sQorHQUv (1 month and 3 days ago)02:10
tinwhiskersI have my bot hat on02:11
BrainstormNew from The Guardian at 00:12 UTC: Anzac Day: Australia coronavirus update latest: Anzac Day dawn services marked in isolation – live news → https://is.gd/6NmdeZ02:22
BrainstormNew from BBC Health at 00:12 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC02:29
BrainstormNew from CNBC Health at 00:33 UTC: (news): Coronavirus live updates: California launches meal delivery program for seniors, US death toll tops 50,000 → https://is.gd/voAMk102:36
BrainstormUpdates for US: +2109 cases (now 924402), +107 deaths (now 52168) since 2 hours ago — Washington, US: +423 cases (now 13176) since 23 hours ago — Texas, US: +364 cases (now 23170) since 8 hours ago02:50
berndjwhere are my italian and spanish oracles? what is public transport like there? is it the dominant mode of transport during normal times?03:03
berndjjust scanning through https://www.medrxiv.org/content/10.1101/2020.04.04.20053058v1.full.pdf and it seems like the home and transport are where infections happen, and everything else is lost in the noise03:03
BrainstormNew from The Guardian at 01:12 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man, 90, in Tasmania dies – live news → https://is.gd/6NmdeZ03:26
BrainstormNew from CNBC Health at 01:45 UTC: (news): California launches meal delivery program for seniors, US coronavirus death toll tops 50,000 → https://is.gd/voAMk103:47
BrainstormNew from https://covid19.specops.network * at 01:52 UTC: ljl-covid: Add Chemical & Engineering News' COVID-19 portal → https://is.gd/7EVAUm03:54
PlanckWalkThere was a Danish(?) study classifying transmission.  Most were in homes, followed by workplaces, social gatherings, then transport but a very large proportion just "unknown".04:04
PlanckWalk(This is after removing "imported" cases)04:05
PlanckWalkNote that workplaces included hospitals, though.04:06
PlanckWalkAlso IIRC homes included nursing homes.04:07
BrainstormNew from The Guardian at 01:52 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man, 90, in Tasmania dies – live news → https://is.gd/6NmdeZ04:09
BrainstormNew from r/WorldNews at 02:16 UTC: worldnews: Coronavirus - The world needs a Chinese investigation, and it's 'owed it': NZ Deputy PM → https://is.gd/xpQ1YW04:37
BrainstormNew from https://covid19.specops.network * at 02:41 UTC: ljl-covid: Add EuroMomo, thought I already had it, but hey → https://is.gd/5bblMW04:44
LjLnixonix, i notice now that the preprint saying 90% of dead doctors they found were male was about, well, doctors. the stuff i've always looked at in italy (while not finding the information you were after, but still, that sort of thing about healthcare workers in Italy) tended to include nurses and other workers. i suspect there's a larger prevalence of women there while there's a prevalence of men among hospital doctors04:50
BrainstormNew from Reddit (test)* at 02:45 UTC: Covid2019: Nurses who got coronavirus fear they will get sick again - Chicago Tribune → https://is.gd/TmsSg604:52
BrainstormNew from https://covid19.specops.network * at 02:56 UTC: ljl-covid: Add studies on antibody production → https://is.gd/a49of304:59
BrainstormNew from https://covid19.specops.network * at 03:01 UTC: ljl-covid: Remove duplicate article → https://is.gd/wPDNU405:06
TramtristThis seems quite an organized channel05:06
LjLi gets more hectic when it's not yet night in europe05:07
LjLright now it's just me adding links to link lists05:07
TramtristThis is the first ive seen this offloop.net chart05:09
TramtristPretty good05:09
tinwhiskersI'm not sure if this has been posted before so apologies if it has, but it calls into question the Santa Clara antibody testing results. I'm not casting judgement but I know quite a few people have been talking about those results so it's worth knowing about I guess: https://www.sciencemag.org/news/2020/04/antibody-surveys-suggesting-vast-undercount-coronavirus-infections-may-be-unreliable#05:09
tinwhiskersTramtrist: why thank you :-)05:09
TramtristI wish we could get antibody testing in the midwest05:11
TramtristThis isnt what I think is true at all .. but i feel the coasts got most of the attention (deservedly) while we in the midwest will be on the tail end of the support05:12
tinwhiskersyeah, it can't come soon enough but things are happening at lightening speed really so we just need to eat some more ramen and wait.05:12
TramtristIts just a feeling reading all about the coasts.. when there seems to be little happening except everything being shut down05:12
TramtristCali has all these tests.. NYC .. I'm sure it's not true but it just feels that way05:13
tinwhiskersfair05:13
BrainstormNew from The Guardian at 03:05 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man, 90, in Tasmania dies – live news → https://is.gd/6NmdeZ05:13
tinwhiskers(I really wouldn't know - not in US)05:13
TramtristI just moved back05:13
TramtristWhat a time to come back...05:13
tinwhiskersgreat timing :-)05:13
tinwhiskerswhere did you come from?05:14
Tramtristjapan05:14
tinwhiskersah. very nice. It ain't all roses there now either though I guess05:14
Tramtristi dunno..05:14
Tramtristfamily says nothings different05:14
tinwhiskersyou'd prefer to be there still?05:14
Tramtristno05:14
Tramtristmedical stuff is still scary when its not your native tongue05:15
tinwhiskersoh, I hear ya there!05:15
Tramtristalso haircuts05:15
tinwhiskerslol. so true05:15
tinwhiskersI can't speak a word to the hairdresser I go to. I have to mime things.05:15
tinwhiskersBut we both find it very funny05:15
tinwhiskersAt the hospital all the signs are in a language I don't speak a word of and I have no idea where to even go.05:16
TramtristI found the best thing was going to the same person over and over05:17
Tramtristeventually you just walk in and they start cutting05:17
tinwhiskersI just stand around looking like a stupid palangi until someone takes pity on me and points me in some direction05:17
Tramtristin silence05:17
tinwhiskersha ha05:17
Tramtristi moved twice in japan05:17
Tramtristit eventually happened05:17
Tramtristboth times05:17
tinwhiskersSo you're not in one of the hot spots in the US then at least?05:17
Tramtristnot at all05:18
Tramtristcinci area05:18
Tramtristkentucky05:18
tinwhiskersTime is probably the best thing in our favour right now05:18
Tramtristthing is.. i know at least 4 people who were very sick had all the symptoms but were denied tests05:18
Tramtristgovernor has done a good job05:18
Tramtristbut05:18
tinwhiskersah. yeah. we certainly hear a lot of that. 05:19
Tramtristi cant understand why they had to be 'presumed'05:19
Tramtristvery strange05:19
tinwhiskershow do you mean, presumed?05:19
Tramtristthey officially had this 'assumed' or 'presumed' with covid?05:19
Tramtristsome line they were getting from the medical people05:20
Tramtristits an unofficial official way of saying sorry we wont test you but you probably have it05:20
tinwhiskersoh. so sent home to quarantine but without a test?05:20
Tramtristyes05:20
Tramtristalways refused a test05:20
BrainstormNew from https://covid19.specops.network * at 03:13 UTC: ljl-covid: Add Cell article about vaccines → https://is.gd/kys27k05:20
tinwhiskersI can only assume it was due to limited supply of test kits05:20
tinwhiskersI doubt there was any malice... It doesn't make sense. What do you think?05:21
Tramtristyeah i hope so05:21
Tramtristproblem was at the same time or weeks before tigers and celebs were getting tests05:21
Tramtristit did not help05:21
tinwhiskersah. right05:22
Tramtristin the end i think they were given anxiety pills and told to go home05:22
Tramtristi heard that from multiple people05:22
Tramtristits my anecdote of the night05:22
tinwhiskersif they had been tested positive they still would have been given that same treatment I guess05:22
Tramtristright05:22
Tramtristthats true05:22
tinwhiskersknowing would be nice though, for sure05:23
Tramtristits the piece of mind knowing its under control that really helps in the end05:23
Tramtristknowing someone did something other than say .. whatever05:23
tinwhiskersyeah05:23
LjL"Recruiting through Facebook likely attracted people with COVID-19–like symptoms who wanted to be tested, boosting the apparent positive rate."05:26
LjLthis is why random sample needs to mean random sample05:26
LjLnot even the NY study was random since people going to supermarkets aren't random05:26
LjLbut at least it wasn't clearly biased in favor of people with symptoms05:26
LjLi don't know whether or not to hope the study made in Italy is compulsory for selected people to participate05:26
LjLif it's not compulsory, people with symptoms will self-select05:26
LjLi don't feel great about "we have to take your blood, whether you want it or not", especially when being anywhere near a hospital is a risk at this time05:27
LjLbut i don't know if this can be evaluated properly otherwise05:27
BrainstormNew from https://covid19.specops.network * at 03:23 UTC: "Tack on" press articles on mortality to the EuroMoMo entry: They aren't really scientific papers or articles but they fit, and it would not make much sense to have them as "news" → https://is.gd/RuREHt05:27
stinkpotshouldn't it be geographically random? or is that not 'random' either?05:27
Tramtristdo any of you feel theres a consensus on when an antibody test will be ready for everyone at any time?05:28
Tramtristhow many months?05:28
Tramtristor years?05:28
tinwhiskersit should clearly be inside the management unit of interest, but then randomly spread geographically.05:29
tinwhiskershrm, actually not necessarily randomly spread geographically.05:29
Tramtristif theres an excess of tests available it doesnt need to be random at all05:30
tinwhiskersIt should be sampled randomly, which should give a representative sample of all regions05:30
Tramtristwe have to hit that at some point05:30
stinkpotdoes that mean throw names into a hat and randomly pull them out?05:30
stinkpoti think there should be some geographical nature to it05:30
Tramtristdidnt iceland use the phonebook?05:31
tinwhiskersstinkpot: yeah, that would be better than drawing people by location05:31
Tramtristread that somewhere05:31
stinkpotlike 'within this 1 square kilometer, we'll randomly select 10% of the population living within this area'05:31
tinwhiskersstinkpot: that's likely to cause a bias 05:32
stinkpotthat's what i was trying to figure out05:32
tinwhiskersunless the 10% you mention is calculated based on density of that area05:32
LjLstinkpot, tinwhiskers: i'd say the wider the test, the more geographical areas it should cover, while keeping them distinct in results. for my country, i can repeat that the intention is to sample 150000 people all over Italy, which is a rather large sample, and the sampling choice will be determined by ISTAT based on age groups, gender, occupation and geographical location05:32
LjLand this should happen "soon"™05:33
tinwhiskersasap05:33
LjLor at least they should be announcing soon that they have selected which antibody tests to use05:33
tinwhiskersoh, I see05:33
LjLtinwhiskers, well it won't have happened before we "re-open" on may 4 for sure05:33
tinwhiskersobviously sampling from the phone book has it's own issues considering how many people aren't in the phone book, and that may be an age-related bias.05:34
BrainstormNew from https://covid19.specops.network * at 03:31 UTC: ljl-covid: Add ScienceMag article critical of antibody tests and their possible … → https://is.gd/sWnFks05:34
Tramtristhttps://www.usatoday.com/story/news/world/2020/04/10/coronavirus-covid-19-small-nations-iceland-big-data/2959797001/05:35
Tramtristya was the phone book i guess05:35
tinwhiskerstruly random samples are tricky to get05:36
LjLtinwhiskers, ISTAT is the entity that makes official census in italy, so they probably won't need the phone book necessarily05:36
LjL%wik ISTAT05:36
BrainstormLjL, from Italian Wikipedia: L'Istituto nazionale di statistica (Istat o ISTAT) è un ente pubblico di ricerca italiano che si occupa dei censimenti generali della popolazione, dei servizi e dell'industria, e dell'agricoltura, di indagini campionarie sulle famiglie e di indagini economiche generali a livello nazionale. → https://it.wikipedia.org/wiki/Istituto_nazionale_di_statistica05:36
LjL%wik :en ISTAT05:36
Tramtristya if you've got census data.... theres your best bet05:36
BrainstormLjL, specify one of the following: Abbott Laboratories — International Society of Transport Aircraft Trading — National Institute of Statistics (Italy)05:37
tinwhiskersyeah, if you have a complete list of residents in some database that's perfect but I wonder if they include minors05:37
tinwhiskersoh, ya. census should have minors too.05:37
LjLtinwhiskers, i think they do, and also census is definitely compulsory, if you get called you must answer or there are fines05:37
LjL%wik :en National Institute of Statistics (Italy)05:37
BrainstormLjL, from English Wikipedia: The Italian National Institute of Statistics (Italian: Istituto Nazionale di Statistica; Istat) is the main producer of official statistics in Italy. Its activities include the census of population, economic censuses and a number of social, economic and environmental surveys and [... want %more?] → https://en.wikipedia.org/wiki/Italian_National_Institute_of_Statistics05:37
tinwhiskersI did get hold of our national census data under NDA one year for a survey we did and of course held on to it afterwards :-/05:38
LjLnaughty05:38
tinwhiskersshhh05:38
LjLanyway i'd pay close attention to the italian results when they come out... maybe it'll be 2021 and everyone else has preceded us, but if i try hard to be less cynical about my country, this should be one of the first really large really random sample antibody study with validated tests05:39
tinwhiskersthat was like back in the late 90's I think. If I recall it took two 1.44MB floppies and caused a problem for all our database software to get arandom sample from, which was the problem I was solving.05:39
tinwhiskersthe solution was trivial of course05:40
LjLput it on a hard drive instead of two floppies? :P05:40
stinkpotis 150000 a big enough sample size in a country of 60-70 million?05:40
tinwhiskerswell, I mean everyone wanted to load the whole thing into memory but no software we had there would load it all.05:40
LjLstinkpot, i would say so05:40
stinkpoti don't see what use it has if it doesn't happen till 202105:41
tinwhiskersit was just a case of running through it twice off disk, once to count, generate random numbers, then run through again to spit out those numbered records.05:41
LjLugh i did not say it won't happen till 202105:41
stinkpotok sorry05:42
stinkpoti never said you said that either05:42
LjLtinwhiskers, clearly you needed a better mmap()05:42
tinwhiskers:-)05:42
LjLstinkpot, it was a hyperbole to say that i hope they won't be late as usual05:42
LjLit is almost definitely happening in 202005:42
LjLhopefully soon05:42
stinkpotwhenever i hear you say 'ugh' i sense deep disappoint 05:43
stinkpotdisappointment05:43
LjLit's just that sometimes it's so hard to say something without being misinterpreted05:43
LjLi'm sure it's at least 50% my fault05:43
LjLtinwhiskers, did you get any earthquake notification btw? some 6-ish in the tonga region05:44
tinwhiskersLjL: there was an earthquake a couple of days ago here but I didn't get an alert. It was only about a 5-ish I think though.05:48
LjLtinwhiskers, no i mean like in the past hour05:48
tinwhiskersOh. no.05:48
BrainstormNew from The Guardian at 03:39 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man, 90, in Tasmania dies – live news → https://is.gd/6NmdeZ05:49
stinkpottinwhiskers: https://earthquake.usgs.gov/earthquakes/eventpage/us60009c06/executive05:49
LjLcloser to Solomon05:49
tinwhiskersPTWC didn't send me anything either05:49
LjLalso pretty shallow05:50
LjLtinwhiskers, well me neither, but it's barely M605:50
tinwhiskersyeah05:50
stinkpottonga wouldn't feel much at that distance05:50
tinwhiskersNo. didn't feel anything. We felt the one a couple of days ago though.05:51
LjLi just saw "Tonga region", didn't look at map05:51
tinwhiskersk05:51
LjLthought it was easier to ask :P05:51
BrainstormNew from https://covid19.specops.network * at 03:47 UTC: ljl-covid: Correct typo → https://is.gd/ptMGhd05:56
BrainstormNew from CNBC Health at 04:02 UTC: Coronavirus live updates: Japan discovers 60 more cases on Italian cruise ship: Japan has confirmed 60 more coronavirus cases among crew members on an Italian cruise ship currently docked in the western Japanese city of Nagasaki for repairs. → https://is.gd/salfAX06:10
BrainstormNew from The Guardian at 04:24 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ06:31
sternenmusik[m]Wonder what we can learn from Diamond Princess. 700 corona infected healthy 70-80 year old humans locked up for 17 days and 6 of them died... 06:36
BrainstormNew from Reddit (test)* at 04:53 UTC: nCoV: UChicago Medicine doctors see 'truly remarkable' success using ventilator alternatives to treat COVID-19 → https://is.gd/BR7TAq07:07
BrainstormNew from CNBC Health at 05:06 UTC: (news): Coronavirus live updates: Japan discovers 60 more cases on Italian cruise ship; India eases some lockdown measures → https://is.gd/salfAX07:14
BrainstormNew from The Guardian at 05:08 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ07:21
BrainstormNew from CNBC Health at 05:37 UTC: (news): Coronavirus live updates: Japan discovers 60 more cases on Italian cruise ship; India eases some lockdown measures → https://is.gd/salfAX07:42
BrainstormNew from The Guardian at 05:44 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ08:04
BrainstormNew from BBC Health at 06:00 UTC: (news): Coronavirus test website to reopen for bookings after 'significant demand' → https://is.gd/N1GvNb08:11
BrainstormNew from CNBC Health at 06:15 UTC: (news): Coronavirus live updates: Japan discovers 60 more cases on Italian cruise ship; India eases some lockdown measures → https://is.gd/salfAX08:18
CoronaBot04/r/coronavirus: Italy, a 23 years old girl has still tested positive for covid19 after 60 days and 6 tests. (10310 votes) | https://redd.it/g7ios508:26
BrainstormNew from The Guardian at 06:29 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ08:39
BrainstormNew from BBC Health at 06:52 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC09:01
BrainstormNew from The Guardian at 06:53 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ09:08
BrainstormNew from BBC Health at 07:14 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC09:22
BrainstormNew from BBC Health at 07:24 UTC: (news): Coronavirus test website reopens for bookings after 'significant demand' → https://is.gd/N1GvNb09:29
truthrit takes about 100 miligrams of covid 19 to infect every human on earth09:30
mefistofeleshah, yes, that's a lot of virus09:31
truthr1 particle for each human i think09:31
truthror you can start with 1 particle and go from there09:31
BrainstormNew from CNBC Health at 07:32 UTC: (news): Coronavirus live updates: Japan discovers 60 more cases on Italian cruise ship; India eases some lockdown measures → https://is.gd/salfAX09:36
aradeshtruthr: surely less than that09:38
aradesh7.5 billion virus particles surely way less than 100mg09:39
aradeshweigh*09:39
tinwhiskersArguably you only need one viral particle to infect every human on Earth... For small values of "arguably".09:42
aradeshmost viruses have a diameter between 20 and 300nm, so let's go with the overestimation of 1000nm, which is 1 micrometer, or 10^(-4)cm. so each virus has volume bounded above by 10^(-12) cm^3. thus 10 billion of them has volume 0.01cm^3 which, assuming the density of water, would only be 10mg09:43
aradeshtinwhiskers: yes, assuming that the human then infects everyone else09:44
aradeshso i guess 100mg you could give each human at least 10 virus particularl.. probably more like 100 or 1000 due to my over estimations :D09:44
aradeshparticles*09:44
truthraradesh: very possible..what does a typical virus particle weight?09:47
truthrinteresting approach you used to reach the mass09:48
aradeshcertainly less than 10^(-12)g09:48
truthrsame density as water good guess09:48
truthrso in your estimate it would take 10 mg?09:48
aradeshyeah, as an upperbound09:48
truthrwow..damn09:49
aradeshlikely less09:49
truthrthat is one potent potential weapon of mass destruction09:49
aradeshbut as tinwhiskers says, you only technically need a single virus particle!09:49
truthrindeed09:49
truthrjust slower a bit09:49
aradeshinfect one person with coronavirus, and the body starts producing billions of them09:49
truthrso a highly infected person could have more than 10 mg of covid 19 in their body?09:50
aradeshwikipedia says that vaccina virus, which is a "large virus" weighs 10^(-17) kg, which is 10^(-15)g09:51
aradeshtruthr: not sure09:51
aradeshsorry09:51
aradesh10^(-14)g09:51
aradeshso seems my very rough estimate was in the right ball park09:51
mefistofelesnot bad heh09:52
truthrnice work09:52
aradeshcovid19 seems to be an established inhabitant of planet earth now09:55
aradeshimpressive how something so tiny has caused so much disruption09:55
mefistofelesaradesh: indeed, though we have plenty already, one more is always a good possibility10:00
mefistofelesand expect more to come10:00
BrainstormNew from r/Italy Live* at 07:58 UTC: /u/pixelcraftables: Buona festa della Liberazione. Mentre eravate via → https://is.gd/GhevSK10:05
mefistofeleshttps://statmodeling.stat.columbia.edu/2020/04/19/fatal-flaws-in-stanford-study-of-coronavirus-prevalence/ 10:10
mefistofelesone that stanford controversial study10:10
mefistofeleson*10:10
BrainstormNew from The Guardian at 08:04 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ10:12
BrainstormNew from BBC Health at 08:23 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC10:33
BrainstormNew from The Guardian at 08:50 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ10:54
BrainstormNew from CNBC Health at 08:53 UTC: (news): Coronavirus live updates: Japan discovers 60 more cases on Italian cruise ship; India eases some lockdown measures → https://is.gd/salfAX11:01
BrainstormNew from BBC Health at 09:00 UTC: (news): Coronavirus test website slots booked up within hour of site reopening → https://is.gd/4LjVjP11:09
BrainstormNew from Reddit (test)* at 09:12 UTC: CoronaVirus_ITALIA: L'Oms lancia un'alleanza internazionale per il vaccino (Ma senza USA e CINA) → https://is.gd/tEXP3F11:16
BrainstormNew from BBC Health at 09:14 UTC: (news): Coronavirus test website slots booked up within hour of site reopening → https://is.gd/4LjVjP11:23
BrainstormNew from The Guardian at 09:16 UTC: Anzac Day: Australia coronavirus update latest: death toll reaches 80 after man dies in Tasmania – live news → https://is.gd/6NmdeZ11:30
mefistofeles%cases Australia11:32
Brainstormmefistofeles: In all areas, Australia, there are 6695 cases (0.0% of the population) and 80 deaths (1.2% of cases) as of 15 minutes ago. 487000 tests were performed (1.4% positive). Fatality can be broadly expected to lie between 0.4% (assuming deaths/cases with ⅔ undetected), and less than 1.5% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Australia for time series data.11:32
mefistofelesnice testing for australia11:33
BrainstormNew from The Guardian at 09:39 UTC: Coronavirus outbreak: Public urged to observe lockdown despite weekend sunshine → https://is.gd/nwLDur11:44
BrainstormNew from r/Italy Live* at 09:50 UTC: /u/pixelcraftables: Mattarella oggi all'Altare della Patria. → https://is.gd/kIp4CK11:51
BrainstormNew from The Guardian at 09:53 UTC: Brazil: Coronavirus live news: Greece prepares to end lockdown as Brazil’s health system nears collapse → https://is.gd/l1n5s211:58
BrainstormNew from CNBC Health at 10:15 UTC: (news): Coronavirus live updates: Japan discovers 60 more cases on Italian cruise ship; Brazil becoming virus hot spot → https://is.gd/salfAX12:20
BrainstormUpdates for Russia: +5966 cases (now 74588), +66 deaths (now 681) since a day ago — US: +1356 cases (now 925758) since 9 hours ago — Mexico: +1239 cases (now 12872), +152 deaths (now 1221) since a day ago12:23
BrainstormNew from BBC Health at 10:20 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC12:27
BrainstormNew from The Guardian at 10:25 UTC: Brazil: Coronavirus live news: Greece prepares to end lockdown as Brazil’s health system nears collapse → https://is.gd/l1n5s212:34
BrainstormNew from BBC Health at 10:37 UTC: (news): Coronavirus test online slots booked up within hour of site reopening → https://is.gd/4LjVjP12:41
BrainstormNew from BBC Health at 10:41 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC12:48
xrogaanMasks are highly recommended in Belgium, but not enforced. They are planning to "reopen" to country too.12:52
xrogaanThey want to provide each citizen with at least one regulated canvas mask.12:53
xrogaanEmployers will have to provide protective equipment to the workers.12:54
xrogaanThey're banking on civilian responsibility. If I take my father as an average, it'll fail.12:55
friedbatis kim jong-un in a coma?12:57
Nsvsonidohttps://www.rawstory.com/2020/04/nyc-poison-control-center-records-jump-in-lysol-and-bleach-cases-after-trumps-remarks/  really?13:01
BrainstormNew from The Guardian at 10:52 UTC: Brazil: Coronavirus live news: Greece prepares to end lockdown as Brazil’s health system nears collapse → https://is.gd/l1n5s213:02
friedbatit's all fake news, expect a few more "lysol is selling out" or "calls into poison control centers on the rise"13:04
friedbatcause you know, drumpf told people to drink bleach or sammitz13:05
friedbatthe guy's been in office for 3 years now, and some people have only one routine: orange man bad13:05
BrainstormNew from BBC Health at 11:00 UTC: (news): Coronavirus test online slots booked up within hour of site reopening → https://is.gd/4LjVjP13:09
friedbatanyone know what's up with belgium? why is their death count so high?13:15
friedbatper capita they're even worse than italy and spain13:15
xrogaansmall country13:16
xrogaanalso depend on how you count. Belgium is very open and count suspected cases.13:16
xrogaanOther countries not so much.13:16
BrainstormNew from The Guardian at 11:10 UTC: Brazil: Coronavirus live news: Greece prepares to end lockdown as Brazil’s health system nears collapse → https://is.gd/l1n5s213:16
friedbatthe size issue should be taken into account when we do per capita right?13:17
xrogaanWe take into account non-confirmed cases, other countries does not.13:18
xrogaanUK's covid-19 death rate is far higher than what the numbers tells. All you have to do is look at the average mortality per week of the last years and compare it to this year, you'll get a figure thousands above average.13:19
friedbati'm not taking about cases13:20
friedbati'm talking about deaths13:20
xrogaanThe resolution of a case can be death too.13:21
friedbati'm not talking about cases13:21
friedbati'm talking about deaths13:21
xrogaanhttps://d34j62pglfm3rr.cloudfront.net/downloads/news/Grafiek_oversterfte.png13:23
friedbati can understand some differentiation between counties on under or over reporting deaths (classifying them as covid or non-covid)13:23
friedbatbut that can't explain the huge differences we see13:23
friedbatbelgium is at 597 deaths per million. germany at 69 deaths per million13:23
xrogaanand new yorkers are drinking bleach.13:24
friedbatthis almost 9 times difference can't be due to reporing13:24
friedbatreporting13:24
friedbatsomething else is going on13:24
friedbatare belgian hospitals overwhelmed?13:24
xrogaanSmall country, disease speading fast. Big country, spread less quickly.13:24
friedbatwikipedia says netherlands has higher population density than belgium13:25
friedbatand netherlands is only at 250 deaths per million13:26
friedbatless than half the belgian rate13:26
xrogaanDoes the netherlands has big commercial ports?13:26
friedbatyou keep changing the story13:26
friedbatreporting differences -> size -> ports13:26
xrogaanDo you understand how a disease spread?13:27
xrogaanNumbers means nothing if they are not put in context. You come here saying "but look at the numbers", without looking at the geopolitical data.13:27
xrogaanDeath per capital is a derivative of whatever numbers gets reported, did you look further than the graphs being show? What did they use to get to the conclusion?13:29
BrainstormNew from r/Italy Live* at 11:51 UTC: /u/pixelcraftables: Immunologia → https://is.gd/S9tddC13:52
BrainstormNew from r/Italy Live* at 11:58 UTC: /u/pixelcraftables: USA - Atlanta → https://is.gd/4vA0eY13:59
BrainstormNew from r/Italy Live* at 12:13 UTC: /u/pixelcraftables: Intrattenimento → https://is.gd/IZAedk14:13
mefistofelesI think it's a bunch of different things contributing for the belgium case14:17
BrainstormNew from BBC Health at 12:16 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC14:20
BrainstormNew from BBC Health at 12:29 UTC: (news): Coronavirus test online slots booked up within hour of site reopening → https://is.gd/4LjVjP14:35
BrainstormNew from CNBC Health at 12:37 UTC: Coronavirus: Brazil becoming hot spot; WHO warns on reinfection: "There is currently no evidence that people who have recovered from Covid-19 and have antibodies are protected," said the WHO. → https://is.gd/salfAX14:42
TramtristHow depressing.. We'll all just keep getting re-infected until we're all gone14:45
Urchin%data croatia14:48
BrainstormUrchin: In all areas, Croatia, there are 2016 cases (0.0% of the population) and 54 deaths (2.7% of cases) as of 16 minutes ago. 30213 tests were performed (6.7% positive). Fatality can be broadly expected to lie between 0.9% (assuming deaths/cases with ⅔ undetected), and less than 5.0% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Croatia for time series data.14:48
BrainstormNew from The Guardian at 12:45 UTC: Coronavirus outbreak: Coronavirus UK: test slots run out for second day running – latest updates → https://is.gd/HzkPWF14:49
BrainstormNew from CNBC Health at 13:00 UTC: (news): Coronavirus live updates: WHO warns about reinfection, US cases top 900,000 → https://is.gd/fxCyay15:03
mefistofeles:o reinfection from WHO, interesting15:04
dTalum so if it's possible for an infection to just go around and around until everyone's dead, why are we still here15:05
dTalis it because society wasn't so connected, and plagues could burn out locally?15:05
mefistofelesdTal: no, that's not what it means15:05
dTalhow so?15:06
dTalIf you can get reinfected, and with ADE it gets worse every time, what's the end game?15:07
dTalIt evolves to be less deadly?15:07
shomalonsurvival of the fittest happens until vaccine15:07
mefistofelesdTal: they just say that it's not clear that having antibodies makes you immune, specially when the antibodies count varies so much from these tests, since not everybody who had the virus has the same antibodies count15:07
mefistofelesread the source15:08
mefistofeleshttps://www.who.int/news-room/commentaries/detail/immunity-passports-in-the-context-of-covid-1915:08
mefistofelesso it is in the context of giving these immunity passports, it's not enough to apss the antibodies test to guarantee immunity, basically 15:08
mefistofeles*pass15:08
dTalmefistofeles, although my comment was sparked by that, I wasn't commenting on it directly15:09
dTalthere doesn't appear to be 100% consensus that infection = immunity15:09
ubLIXhow could there be? far too soon for a well defined answer to that question15:10
mefistofelesdTal: yes, more studies are needed15:10
mefistofelesthere's a famous one in macaques that showed no possibility of reinfection15:10
BrainstormNew from r/Italy Live* at 13:08 UTC: /u/pixelcraftables: Belgio → https://is.gd/bFeTER15:10
dTalso, in the scenario where infection != immunity, what happens?15:10
shomalonreinfection15:10
mefistofelesdTal: depends on wht the mechanism actually is that allows reinfection and how the body cleared the virus in the first place15:11
mefistofelesshomalon: no15:11
mefistofelesnot necessarily15:11
dTal...I thought that was definitionally what immunity was? can't be reinfected?15:11
mefistofelesit's subtle, but yeah, if we take that as a definition, then sure, it means reinfections if there are no immunities, by your definition15:12
shomalonBut if an individual is exposed to the virus again and has lost the temporary immunity or never had immunity, then the chances of them being reinfected are far higher than if they had immunity15:12
mefistofelesshomalon: true15:12
shomalonHence reinfection is likely considering the current spread of the virus. This is why mitigation techniques are essential15:13
dTalmefistofeles: sorry, what's the actual definition then? I'm a bit confused15:14
mefistofelesdTal: there are many levels15:14
mefistofelesIn biology, immunity is the balanced state of multicellular organisms having adequate biological defenses to fight infection, disease, or other unwanted biological invasion, while having adequate tolerance to avoid allergy, and autoimmune diseases. 15:14
mefistofelesfrom wikipedia15:14
mefistofelesso you can see it involves already many different things15:14
dTalin practical terms, what does it mean to say that someone is not immune, but it's not necessarily true they can get reinfected?15:16
dTalcan you give an example?15:17
mefistofelesyes, but again, that's a simiplification15:17
Streakerif you can't get infected you are immune15:17
Streakerby definition15:17
BrainstormNew from BBC Health at 13:12 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC15:17
dTalStreaker: I already said that but mefistofeles says there's more subtlety to it15:18
dTalbut I'm having trouble getting him to expand on that15:18
mefistofelesdTal: nevermind, it's not needed to go into details15:19
Streakerif something cannot be explained, then it isn't true15:20
mefistofelesheh15:20
shomalonStreaker yes, but the immunity in this case has an expiration date15:20
Streakerimmunity always has an expiration date15:20
dTalEr, okay. So returning to my original question, if infection doesn't confer immunity, then what stops the virus going in circles forever until we're all dead? Particularly if each infection is worse than the last, due to ADE15:21
mefistofelesanyways, immunity is not guaranteed by antibodies, as far as it's known15:21
StreakerCovid-19 is not something special. The vaccines you got as a child will not give you immunity forever.15:21
mefistofelesfor this disease15:21
Streakerfamously, measles has the ability to "erase" your memory of other viruses, so getting measles means you lose immunity to a bunch of other diseases15:22
BrainstormNew from The Guardian at 13:15 UTC: Coronavirus outbreak: Coronavirus UK: test slots run out for second day running – latest updates → https://is.gd/HzkPWF15:24
mefistofeles%cases UK15:25
Brainstormmefistofeles: In all areas, United Kingdom, there are 143464 cases (0.2% of the population) and 19506 deaths (13.6% of cases) as of 6 hours ago. 612031 tests were performed (23.4% positive). See https://offloop.net/covid19/?default=United%20Kingdom for time series data.15:25
mefistofelesI wonder how the WHO asses these things? do they have experts everywhere working for them and getting paid for validating/studying all these sources of information?15:28
mefistofelesseems like a really complicated thing to manage15:28
ubLIXdidn't read WHO on this point. was there anything of substance in their pronouncement other than "please bear in mind 'absence of evidence'"?15:31
BrainstormNew from BBC Health at 13:27 UTC: (news): Coronavirus: Plea for public to get medical care when they need it → https://is.gd/KoOBgC15:31
mefistofelesubLIX: no, not really15:32
mefistofelesubLIX: but once they make these pronunciations commonly means that these rumors and preliminary studies are gaining support and building up evidence15:32
mefistofelesso it's something too look up, if you haven't already15:33
ubLIXhugely naive question, but given gathering suppositions that versions of sars-cov-2 have been widespread everywhere longer than previously thought, is it plausible to conceive of the severe forms of covid-19 appearing since january as an ADE second wave?15:43
ubLIXnot an original thought, i assume15:44
mefistofelesubLIX: what do you mean by versions? like showing difference genome?15:48
mefistofeles*different15:48
ubLIXjust extra hand-waving wiggle room to allow for sars2 to be older than thought; flu seasons for the last three years have been unusually bad. but it's rare (isn't it?) to have species of infection assayed during flu illness; rather, it's just "stay home, rest, antibiotics for secondary infection maybe"15:52
kreyrenAccording to wiki covid-19 in severe conditions has a symptom of confusion, any more info on that?15:52
kreyreni.e confusion caused by fever or?15:52
kreyrenalso apparently coughing up blood.. from what?15:53
mefistofelesubLIX: for humans? Not likely tbh15:53
BrainstormNew from r/Italy Live* at 13:46 UTC: /u/pixelcraftables: Italia → https://is.gd/h6aBhI15:53
BrainstormUpdates for Spain: +3995 cases (now 223759), +378 deaths (now 22902) since a day ago — Saudi Arabia: +1197 cases (now 16299) since a day ago — Iran: +1134 cases (now 89328), +76 deaths (now 5650) since a day ago15:54
mefistofelesubLIX: I mean, how could you explain not being detected before?15:55
ubLIXyes, highly unlikely, i agree15:56
ubLIXbut i suppose the thoughts would be: flu like illness, not very severe, test for known flu viruses comes back negative, oh well it wasn't that severe anyway, no further enquiry made15:57
ubLIXwrt to heightened flu seasons 2017-201915:58
oribaLjL: You once asked, why covid-19 mortality is so low in germany. Did you find answers?15:59
ubLIXand assuming earlier versions/mutations/pre-ADE weren't severe enough to warrant unusual intervention (usual being stay home and rest)16:00
mefistofelesubLIX: ok, yes, but having a big jump all of a sudden and stopping just there is not really something that happens, as far as biology goes16:00
ubLIXyep. anyway, just idle naive speculation16:00
mefistofelesubLIX: yeah, I get it16:01
generawhat is ADE?16:01
ubLIXgenera: https://en.wikipedia.org/wiki/Antibody-dependent_enhancement16:02
mefistofelesoriba: you asked LjL , but the common explanation is a set of different factors, the one with more impact is probably extensive testing16:02
generatnx16:02
mefistofelesoriba: also that it exploded in Germany in rather younger people instead of elderly as in Italy... but also probably because Italy has many many more cases and deaths exploded just when it hit elderly, but it was already spreading in the community for weeks... antibodies tests data are suggesting such scenarios in many countries already16:04
Nick01Hey guys...16:05
Nick01Anyone around?16:06
mefistofelesNick01: sure16:06
Nick01Where you from?16:07
Nick01<---- USA16:07
Nick01Wondering when the gov is going to open back up16:07
BrainstormNew from Ars Technica at 14:00 UTC: Gaming & Culture: Games getting us through COVID-19—blocks, roguelites, whatever Death Stranding is → https://is.gd/iOQXwP16:07
oribamefistofeles: I have three things: 1) different age profile in infections. 2) good ICU doctors, 3) germany has no efficient good working reporting on the deaths. The last one is the reason why EUROMOMO z-score looks good in germany, and bad in UK.16:08
oribamefistofeles: only Berlin and Hessen do good reporting - but the most cases are in NRW16:08
oriba(and bavaria also has many cases I think)16:08
BrainstormNew from The Guardian at 14:05 UTC: Farmers turn to homegrown force to bring in the harvest: With Covid-19 keeping eastern Europeans away, furloughed British workers are signing up to fill seasonal vacancies – but will there be enough of them? → https://is.gd/qXjRb416:14
mefistofelesoriba: yes, Euromomo only has Berlin and Hesse, that doesn't mean other's are not reporting16:15
mefistofelesthey just don't report to Euromomo16:15
mefistofelesbut data is there, you can check the RKI bulletins and the dashboard16:15
mefistofelesoriba: yes, the ICU thing also helps, specially comparing to countries where hospitals got filled16:16
oribamefistofeles: ok, they don't report to euromomo and thats why it looks good there.16:17
oribamefistofeles: possibly, when the infection goes to higher ages, situation will become worse16:17
mefistofelesoriba: depends, in terms of numbers? sure, but the infection is already passed a peak16:18
mefistofelesunless people become massively careless and don't obey the distancing measures, it should be ok16:19
mefistofelesoriba: and that already happened, that'swhy the case fatality rate steadly increased for days/weeks for Germany, from 0.1 to 2% or so16:19
oribamefistofeles: if other age will become infected, more deaths will occur16:19
mefistofelesnow, what I'm not sure is whether Germany is extensively testing post-mortem16:20
oribamefistofeles: we will see, what will happen, when the soft lockdown will become even softer - but masks will be used, this may help16:20
mefistofelesand how many deaths outside hospitals it had, but I don't think it would be that significant, since hospitals weren't even filled to being with16:20
oribaa lot of people avoided going to hospital16:21
oribamaybe they die not because of covid, but because they didn't went to hospital with their heart-diseases etc16:22
mefistofelesmaybe, but if it were that crucial that would be considered in the baseline16:23
mefistofelesso not really an excess of deaths16:23
mefistofelesI mean, no that high, as seen by other countries16:23
mefistofelesnot*16:23
mefistofelesand that's why it's also important to relax distancing lockdown, many people are not getting treated because of these things16:24
mefistofelesI even have a room mate already having some troubles because of it16:24
BrainstormNew from r/Italy Live* at 14:24 UTC: /u/pixelcraftables: Regno Unito → https://is.gd/b5pwKS16:28
BrainstormNew from Reddit (test)* at 14:33 UTC: CoronaVirus_ITALIA: Top 10 Countries in Europe by Coronavirus Deaths (March 15 - April 24) → https://is.gd/ICAGdO16:36
LjLoriba, i was skeptical that extensive testing alone did it, but i may need to revise that position given some recent antibody tests... but anyway, i still think it's a combination of factors: more testing but also many more ICU beds available. also, at first it had a *really* low rate... not it is at least exceeding the 1% that was predicted initially (at least apparently)16:37
BrainstormUpdates for United Kingdom: +4913 cases (now 148377), +813 deaths (now 20319) since 23 hours ago — US: +496 cases (now 927026) since 52 minutes ago — Florida, US: +306 cases (now 30839) since 16 hours ago16:39
xrogaan%title https://www.reddit.com/r/Coronavirus/comments/g7ios5/italy_a_23_years_old_girl_has_still_tested/16:40
Brainstormxrogaan, the URL could not be loaded 16:40
xrogaandTal: ^16:40
xrogaanI don't speak Italian, so I trust the english commentator of that thread.16:41
LjLmaybe i should fake my useragent for %title, eh16:41
LjLalso i can read italian but i'd say deepl looks like it did a decent job :P16:42
BrainstormNew from CNBC Health at 14:37 UTC: (news): Coronavirus live updates: WHO warns about reinfection, US cases top 900,000 → https://is.gd/fxCyay16:43
xrogaan:)16:45
xrogaanIt really annoys me that politics use white lies about the pandemic.16:46
LjLtoo bad DeepL doesn't seem to do website translations the way google does16:49
BrainstormNew from BBC Health at 14:45 UTC: (news): Coronavirus test online slots booked up within hour of site reopening → https://is.gd/4LjVjP16:50
BrainstormNew from The Guardian at 14:45 UTC: World leaders agree to cooperate on coronavirus vaccine, but US does not take part – video: Global leaders have pledged to accelerate cooperation on a Covid-19 vaccine and to share research, treatment and medicines around the globe as part of a World Health Organization initiative. → https://is.gd/t0S5qR16:57
LjL%title https://www.independent.co.uk/news/world/americas/us-politics/coronavirus-trump-treatment-disinfectant-bleach-new-york-a9483786.html16:57
BrainstormLjL, the URL could not be loaded 16:57
Specwhy would US lead the world in anything? that's boring16:58
LjL> The city’s Poison Control Centre managed 30 cases from Thursday evening until Friday afternoon, a spokesperson told New York Daily News – more than double the number of cases the centre dealt with over the same period last year.16:58
LjLSpec, yeah it's gotten kind of old16:58
mefistofelesSpec: not only boring but dangerous :P16:58
CoronaBot04/r/coronavirus: San Francisco mayor says city's PPE orders have been diverted, confiscated: It 'blows my mind' (10104 votes) | https://redd.it/g7nbp317:04
BrainstormNew from r/WorldNews Live* at 15:03 UTC: /u/slakmehl: No evidence that recovered COVID-19 patients cannot be reinfected: WHO - Reuters → https://is.gd/duc1AM17:04
mefistofelesI don't really know how goverments joining forces means for a vaccine...17:05
mefistofeless/means/works17:05
LjLwell maybe it'll mean the first country that finds a vaccine won't confiscate all the supply for itself17:05
mefistofelesbut that's up to the company developing it, isn't it?17:06
LjLlike *some* countries were expected to do after *some* allegedly attempted buyouts of *some* companies in other countries17:06
LjLnot really, if the government confiscates it...17:06
mefistofelesthough maybe it helps in that way that CHina is more advanced, asince most (every?) companies are state owned17:06
mefistofelesLjL: is that common? I don't see that happening in many countries, tbh17:08
LjLmefistofeles, there was one big incidents that i know of, that was it afaik17:09
mefistofelesok17:10
mefistofelesthat may be enough, this one is big17:10
BrainstormNew from CNBC Health at 15:05 UTC: (news): Coronavirus live updates: NY nursing home sees a burst in Covid-19 infections, US cases top 900,000 → https://is.gd/fxCyay17:11
LjL%cases uk17:12
BrainstormLjL: In all areas, United Kingdom, there are 148377 cases (0.2% of the population) and 20319 deaths (13.7% of cases) as of 14 minutes ago. 640792 tests were performed (23.2% positive). See https://offloop.net/covid19/?default=United%20Kingdom for time series data.17:12
LjLmore cases and more deaths today i think17:12
livebrainso uk seems to be undertesting 17:13
LjL"seems"17:14
Specoh, we're boutta break 1 milly17:16
Spec100k in 3 days, oh my17:16
mefistofeleslivebrain: yes, pretty undertested there17:16
livebrain%data portugal17:18
Brainstormlivebrain: In all areas, Portugal, there are 23392 cases (0.2% of the population) and 880 deaths (3.8% of cases) as of 20 minutes ago. 330512 tests were performed (7.1% positive). See https://offloop.net/covid19/?default=Portugal for time series data.17:18
BrainstormUpdates for US: +2002 cases (now 929028), +107 deaths (now 52371) since 51 minutes ago — Maryland, US: +1150 cases (now 17766), +77 deaths (now 875) since a day ago — Chile: +552 cases (now 12858) since 23 hours ago17:25
BrainstormNew from The Guardian at 15:17 UTC: Coronavirus outbreak: Coronavirus US live: Trump team mulls briefing changes in wake of disinfectant row → https://is.gd/w1kAAn17:25
BrainstormNew from CNBC Health at 15:27 UTC: 'Science will come through': Doctor who pioneered HIV treatment discusses potential Covid-19 drugs: Dr. David Ho's lab pioneered treatment approaches to HIV. Now, his focus is Covid-19, or, more specifically, SARS-CoV-2, the virus that causes Covid-19. → https://is.gd/MY17M717:33
BrainstormNew from r/Italy Live* at 15:37 UTC: /u/pixelcraftables: USA → https://is.gd/8U5np117:40
BrainstormNew from CNBC Health at 15:38 UTC: (news): Coronavirus live updates: NY nursing home sees a burst in Covid-19 infections, UK death toll tops 20,000 → https://is.gd/fxCyay17:47
Butterfly^https://i.imgur.com/aleQqSH.jpg  Trump killing people, again17:51
intranutis the covid-19 mutating?17:54
BrainstormNew from r/Italy Live* at 15:53 UTC: /u/pixelcraftables: AGGIORNAMENTO 25/04/2020 ORE 17.00 POSITIVI AL nCov Regione ess INCREMENTO Terapia coe pecepuri| casiToTAaLi | CAS! TOTAL! | tamponi | casi TESTATI inten attualmente | GUARITI (rispetto al giomo intensiva a precedente) Lombardia 8.489 724 25.260 34.473 Piemonte 2.937 238 12.327 15.502 93.325 [... want %more?] → https://is.gd/iTwu5R17:54
LjLintranut, all the time17:54
mefistofelesButterfly^: how can people be so stupid? :/17:59
Butterfly^Trump became POTUS, i think that alone explains enough18:00
BrainstormNew from CNBC Health at 15:56 UTC: (news): Coronavirus live updates: '21 days of hell': NY gov on state's death rate, UK fatalities top 20,000 → https://is.gd/fxCyay18:01
LjL%cases italy18:02
BrainstormLjL: In all areas, Italy, there are 192994 cases (0.3% of the population) and 25969 deaths (13.5% of cases) as of 14 minutes ago. 1.6 million tests were performed (11.8% positive). See https://offloop.net/covid19/?default=Italy for time series data.18:02
rmonten[m]<intranut "is the covid-19 mutating?"> Yes, this website gives a cool overview of detected mutations: https://nextstrain.org/ncov/global18:02
LjLso WHY NO UPDATE18:02
LjLgeeee18:02
l0ndonero/.....18:02
sternenmusik[m]I dont feel well. 18:05
sternenmusik[m]<sternenmusik[m] "I dont feel well. "> Again. This attacks come and go. 18:06
BrainstormNew from r/Italy Live* at 16:04 UTC: /u/pixelcraftables: Statistica → https://is.gd/bkvJAb18:08
Raf[m]> > <@freenode_intranut:matrix.org> is the covid-19 mutating?18:10
Raf[m]> Yes, this website gives a cool overview of detected mutations: https://nextstrain.org/ncov/global18:10
Raf[m]3604 genomes. Does this imply there are 3604 mutations at least?18:10
BrainstormUpdates for Italy: +2357 cases (now 195351), +415 deaths (now 26384) since 23 hours ago — US: +813 cases (now 929841), +472 deaths (now 52843) since 53 minutes ago — New York, US: +437 deaths (now 21728) since 5 hours ago18:10
BrainstormNew from The Guardian at 16:05 UTC: Coronavirus live news: ‘No evidence’ you can’t get Covid-19 twice, says WHO: Greece prepares to end lockdown; Bill Gates vows to fund vaccine production; Australia and New Zealand mark Anzac Day from driveways → https://is.gd/l1n5s218:16
BrainstormNew from Reddit (test)* at 16:28 UTC: Aggiornamento 25/04: submitted by /u/maikk_ to r/CoronaVirus_ITALIA → https://is.gd/ZTqs5h18:30
BrainstormUpdates for Turkey: +2861 cases (now 107773), +106 deaths (now 2706) since a day ago — US: +385 cases (now 930226) since 34 minutes ago — Minnesota, US: +261 cases (now 3446) since a day ago18:35
BrainstormNew from CNBC Health at 16:30 UTC: (news): Coronavirus live updates: '21 days of hell': NY gov on state's death rate, UK fatalities top 20,000 → https://is.gd/fxCyay18:37
l0ndonerLjL: does Italy count nursing home deaths in the figures?18:40
BrainstormNew from The Guardian at 16:32 UTC: Coronavirus UK: no date for ending lockdown, says Priti Patel – video: Priti Patel has said removing coronavirus restrictions in the UK will not be a binary choice and the government would not give a date for the end of lockdown. The home secretary added that five tests will have to be met before schools can reopen [... want %more?] → https://is.gd/xnSv3N18:44
LjLl0ndoner, mostly no18:45
LjLl0ndoner, only if they were tested, which is, in most cases, no18:45
LjLit does include deaths at home, though, again if they were tested (which is... in some cases), unlike the UK18:46
l0ndonerhappy liberation day my friend 18:47
LjLoh, right18:48
LjLi think yesterday's Corriere came with a free italian flag18:49
livebrain%data new york18:49
Brainstormlivebrain: In New York, US, there are 277445 cases (1.4% of the population) and 21728 deaths (7.8% of cases) as of 15 minutes ago. 730656 tests were performed (38.0% positive). See https://offloop.net/covid19/?default=New%20York for time series data.18:49
LjLuhm18:49
LjLif that's 1.4% of the population18:49
LjLbut in reality they found that 14% or so had antibodies18:49
LjLthen it means the IFR is 0.78% instead of 7.8%18:50
LjLi mean, i know these kinds of considerations have already been made, but i hadn't looked at the numbers recently18:50
BrainstormNew from r/Italy Live* at 16:51 UTC: /u/pixelcraftables: Immunologia → https://is.gd/iOWc2518:52
BrainstormNew from CNBC Health at 16:55 UTC: (news): Coronavirus live updates: NY Gov. Cuomo on '21 days of hell,' UK fatalities top 20,000 → https://is.gd/fxCyay18:59
nixonixoriba: if you know euromomo better, howcome austria has significantly less deaths than average? maybe the last week has missing data, but also the previous week19:06
LjLtry not to use the reply feature in too much layers on Matrix please... it just gets impossible to read on IRC19:07
Raf[m]My bad19:07
rmonten[m]sry19:07
LjLit's okay, just saying19:08
oribanixonix: I don't know details about austria. I just have heard the information that germany does not report properly to Euromomo, which may be the reason that germany looks good there. Only two federal states of germany report regularly and quick to Euromomo, and those two have comparingly less problems. So those fed. states with high numbers are not shown there. Not sure if this will be19:11
oribacorrected later, or if there are corrections somehow. Euromomo should show more details on the reporting, I think.19:11
BrainstormNew from CNBC Health at 17:07 UTC: (news): Coronavirus live updates: Beaches reopen around the US, NY Gov. Cuomo says state has seen '21 days of hell' → https://is.gd/fxCyay19:13
rmonten[m]Does anyone know how reliable the latest couple of weeks reported by euromomo are? Week 16 shows a decline in mortality, but is this likely to be corrected later?19:16
nixonixoriba: is the german mortality data available anywhere? (exp berlin and hesse, that euromomo has) especially the very recent, from april19:16
BrainstormUpdates for US: +11252 cases (now 941478), +78 deaths (now 52948) since 46 minutes ago — New York, US: +9800 cases (now 287245) since an hour ago — Brazil: +1181 cases (now 55224), +58 deaths (now 3762) since 7 hours ago19:20
oribanixonix: I don't know19:21
oribanixonix: maybe RKI-dashboard?19:21
LjLrmonten[m], probably not very reliable, i'm not sure if they still show this on their new site layout but they had a "delay-corrected mortality" line or some other similar term before, and i didn't quite understand what that was, but it was clearly *some* kind of extrapolation from missing data19:21
oribanixonix: from time to time they add some new stuff here: https://experience.arcgis.com/experience/478220a4c454480e823b17327b2bf1d419:22
rmonten[m]I see, thanks19:23
BrainstormNew from r/Italy Live* at 17:35 UTC: /u/pixelcraftables: Tecnologia → https://is.gd/4TTKl719:35
BrainstormUpdates for US: +3771 cases (now 945249), +295 deaths (now 53243) since 19 minutes ago — New Jersey, US: +3327 cases (now 105523), +246 deaths (now 5863) since 22 hours ago — Louisiana, US: +372 cases (now 26512) since 16 hours ago19:35
ketas!risk 11519:38
ketasoh no19:38
CovBotThe risk model only handles ages between 0 and 110.19:38
ketas!risk 11019:38
ketasoh indeed19:38
CovBotI estimate a 110 year old patient sick with COVID-19 has a 42.2% chance of survival, a 61.8% likelihood of needing to go to hospital, a 24.7% risk of needing intensive care there and a 57.8% chance of death.19:38
BrainstormNew from CNBC Health at 17:39 UTC: (news): Coronavirus live updates: Beaches reopen around the US, NY to expand testing after '21 days of hell' → https://is.gd/fxCyay19:42
Atque!risk 45019:45
CovBotThe risk model only handles ages between 0 and 110.19:45
AtqueDamn19:45
l0ndonerA bit off track I've been asked to download zoom .deb is it a security risk and feeding data to china?19:53
Butterfly^https://twitter.com/rickygervais/status/706465063599808512?lang=en  tweet from 2016 !!!19:56
generayes19:59
AimHereI'm under the impression that it's a security risk because random dweebs will jump in your Zoom calls and spam you with Nazi Hentai or worse20:03
BrainstormNew from r/Italy Live* at 18:00 UTC: /u/pixelcraftables: Germania - Berlino → https://is.gd/YVLrix20:04
tinwhiskersI thought zoom immediately added an option to address that particular concern20:07
BrainstormNew from CNBC Health at 18:03 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay20:11
oribatinwhiskers: If you look for another idea for your graphs: what about cases per density of population?!20:23
tinwhiskersoriba: the population option is there if you tick "by population" but I don't have any population density data.20:24
tinwhiskersThat would be kinda interesting though20:24
oribayes, interesting... thats why I mention it. I had no time to start my own analysis. Just downloading data atm.20:25
BrainstormNew from r/Italy Live* at 18:23 UTC: /u/pixelcraftables: Italia → https://is.gd/o7WDBM20:25
mefistofelesoriba: https://rcolyer.net/covid19/20:29
tinwhiskersoriba: if you get a decent density dataset together point me at it and I'll add it in20:29
mefistofelesmaybe you find it useful20:29
tinwhiskersAh20:29
mefistofelesI mean, it just get the population and divides20:30
mefistofelespopulation data from 2018, it seems20:30
tinwhiskersmefistofeles: we have it by population already. oriba is referring to population density as opposed to population20:31
mefistofelestinwhiskers: ah! sorry, misread20:31
oribatinwhiskers: Wikipedia? Wikidata?20:33
oribafor the datasets20:33
oribamefistofeles: nice graphs, but not vs. pop. density20:34
tinwhiskersYeah, the population data came from Wikipedia so happy to have density data from the same. 20:34
oribatinwhiskers: so, you will add it?20:35
tinwhiskersIt may not be the most accurate but it only needs to be about right, and to be fair Wikipedia was still very good compared to most20:35
tinwhiskersoriba: I'll do a quick test in dev where I replace popn with density and we can take a look at that and see if it merits its own option20:36
oribanice20:37
tinwhiskersMy brain is struggling with some minor details... We report the population figures per 100,000 population... What would that be when using density?20:39
BrainstormNew from CNBC Health at 18:37 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay20:40
friedbathow do you mean density?20:40
friedbatpopulation/area ?20:41
CoronaBot04/r/coronavirus: We regret to inform you that your inflatable T. rex costume is not virus-proof (10044 votes) | https://redd.it/g7tche20:41
tinwhiskerscases per 100,000 popn per km²20:41
tinwhiskersHrm20:41
tinwhiskersfriedbat: yeah20:42
friedbati don't think that makes sense20:42
tinwhiskersNo20:42
friedbatbut you might want to plot deaths vs pop/area20:42
tinwhiskersfriedbat: that's the same thing20:43
tinwhiskers(except deaths instead of cases)20:43
tinwhiskersOh, sorry. I see20:43
tinwhiskersSo oriba, we just need land area since we already have population20:44
tinwhiskersI... May already have that20:44
sternenmusik[m]There is something terrible wrong about disease x. 20:46
friedbatif you have deaths per 100k, call it dpk. and you want death/(pop/area) you would do dpk*(area/100000)20:46
tinwhiskersOk. Thanks friedbat20:47
BrainstormNew from The Guardian at 18:38 UTC: Coronavirus live news: global death toll passes 200,000: Greece prepares to end lockdown; Bill Gates vows to fund vaccine production; Australia and New Zealand mark Anzac Day from driveways → https://is.gd/l1n5s220:47
friedbatbut i don't think deaths/(pop/area) tells you anything20:47
sternenmusik[m]<friedbat "but i don't think deaths/(pop/ar"> What? 20:48
tinwhiskersNo, but cases by density would be interesting20:49
sternenmusik[m]You are political motivated human bots. 20:49
sternenmusik[m]Ignoring the truth. 20:49
friedbatyes, i agree, i would plot deaths per capita (y axis) versus density (x-axis)20:49
tinwhiskersAh.... Yes20:49
friedbati would expect a positively sloped line of best fit20:49
tinwhiskersoriba: hold on a sec20:50
BrainstormUpdates for Peru: +3683 cases (now 25331), +66 deaths (now 700) since 23 hours ago — France: +1660 cases (now 161488), +369 deaths (now 22614) since a day ago — Canada: +652 cases (now 45016), +106 deaths (now 2456) since an hour ago20:51
sternenmusik[m]Hello? You completely ignore what is actually happening and keep on doing your statistics? 20:51
tinwhiskerssternenmusik[m]: what are we ignoring?20:52
sternenmusik[m]Thanks for listening.20:53
tinwhiskersOh you wanted some attention. Sorry.20:53
sternenmusik[m]No. 20:53
tinwhiskersWhat are you doing here sternenmusik[m] instead of solving the problem? It's like you're just ignoring it.20:54
BrainstormNew from CNBC Health at 18:50 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay20:54
oribatinwhiskers: if I would have some more experience with sparql, I would lookup datasets on Wikidata. But it's a while ago that I played with it, and never was that deep into it. It should be easy to get the data there (if not otherwise scraping wikipedia-pages).20:56
tinwhiskersoriba: I'm not exactly sure what you want from these plots.20:56
tinwhiskersI was imagining a scaling factor like with population, but not sure that's sensible. 20:57
friedbatwhat is the risk model doing with age?20:57
oribatinwhiskers: just an idea. if it's too much work, ignore it ;-)  But higher population density means people are closer together...20:57
tinwhiskersoriba: yeah20:58
sternenmusik[m]Doesnt make any difference. 20:59
oribatinwhiskers: someone who seems to believe the covid-thing is rather a fake, asked: why only industrial ("first world" countries have high infections and death rates, and poorer countries not. My idea: higher pop. density might be a reason (plus. so called lifestyle diseases).20:59
tinwhiskersoriba: when I get out of bed I'll have a look on a computer and try to think about it better20:59
sternenmusik[m]Check how many old peoples homes are infected and you get closer to the truth. 21:00
oribatinwhiskers: ah, you want to go to bed now?21:00
friedbatbut keep in mind density has a weird dimension. so you could have a town with population 1200 and a density of 3 people/km^2 and a city of 1,000,000 also with population 3 people/km^2 and you would expect different *levels* of cases or deaths in each21:00
tinwhiskersoriba: don't go to any effort in the meantime though21:00
tinwhiskersoriba: no I've just woken up21:00
friedbattherefore you're have to plot density vs. things like cases/100k and deaths/100k or so21:01
oribatinwhiskers: ah, ok.21:01
BrainstormNew from r/Italy Live* at 18:55 UTC: /u/pixelcraftables: Francia → https://is.gd/6moMCq21:01
tinwhiskersfriedbat: yeah. Cheers21:03
friedbati said population up there for the city and meant density21:04
oribapop. density, just three countries: germany: 233 people per (km)^2, Japan: 335.8, Kenia: 82.21:04
storgehttps://www.usatoday.com/story/news/2020/04/24/usda-let-poultry-plants-move-faster-crowd-lines-covid-coronavirus-spread-meat-packing-workers/3013615001/21:06
BrainstormUpdates for Brazil: +2158 cases (now 57382), +156 deaths (now 3918) since an hour ago — US: +564 cases (now 946397), +189 deaths (now 53455) since 18 minutes ago — Michigan, US: +562 cases (now 37203), +189 deaths (now 3274) since a day ago21:06
BrainstormNew from r/Italy Live* at 19:03 UTC: /u/pixelcraftables: OMS → https://is.gd/nNneBn21:09
LjLi wanted to do something with population density in Brainstorm but honestly i don't know what21:11
LjLaside from just it mentioning it21:11
LjLin charts, it may work, for correlations or whatnot21:11
LjLbut other than that not sure what i could use it for21:11
tinwhiskersLjL: yeah so for comparing totals between countries on two axes as friedbat describes I agree. But as a drop in scaling factor like population over time series data like I was originally thinking, my brain is struggling to process right now.21:14
LjLtinwhiskers, no i'm not sure that makes sense, but "comparing totals between countries on two axes" is basically a correlation chart, so yeah that one does make sense to me21:15
LjLalthough you could do it with a number of other things too21:15
LjLtemperature21:15
LjLi know we don't really believe in temperature affecting this21:15
LjLbut one could do it21:15
tinwhiskersStill if you just applied those example density numbers oriba just gave as a scaling factor it might *look* interesting21:16
tinwhiskersLjL: yeah21:16
friedbatthe one issue i see with correlation graphs comparing countries (per capita deaths vs. density, for example) is that countries might be at different stages of the virus curve21:16
tinwhiskersfriedbat: yeah, there's less of an issue when looking at time series data21:18
friedbatso you'd have to account for that. maybe by taking the numbers at a certain time (say 30 days since they hit 1 death per million)21:18
friedbator something21:18
tinwhiskersIf you're just comparing totals that's certainly a problem21:18
mefistofelestinwhiskers: I have the pop density by countrie21:19
mefistofelescountry*21:19
tinwhiskersfriedbat: the graphs already have the option to align based on some arbitrary case count21:19
mefistofelesin a CSV file21:19
tinwhiskersmefistofeles: oh. Well... Sweet21:19
mefistofeleswould that work?21:19
friedbattinwhiskers: but case count won't help21:20
tinwhiskersYeah, worth chucking it in and seeing what happens. 21:20
friedbatthat's the correlation you're after anyways21:20
tinwhiskersfriedbat: I'm talking about time series data though, not correlations21:20
tinwhiskersI'm also very confused though21:20
mefistofelestinwhiskers: giving you the link in private msg21:21
tinwhiskersmefistofeles: thanks21:21
BrainstormNew from CNBC Health at 19:20 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay21:23
friedbatso i'm reading about re-infection from WHO (though it's the WHO so who knows if it's bullshit or not)21:23
friedbatbut then i'm also reading studies done on monkeys showing re-infection doesn't occur21:23
friedbathere's a recent "no re-infection" paper https://www.biorxiv.org/content/10.1101/2020.03.13.990226v121:24
tinwhiskersthe WHO announcement is some sort of half-truth that is horribly confusing for people21:25
LjLmefistofeles, tinwhiskers already has the population density by country, actually21:26
tinwhiskersOf course some people are getting protection for some period of time21:26
LjLnot sure if he realizes but he does :P21:26
tinwhiskersLjL: yep. I just got that21:26
mefistofelesLjL: ah well, xD21:26
friedbattinwhiskers: what is up with the who's incompetence?21:27
tinwhiskersI'm not sure it's incompetence. It's the natural outcome from a large committee21:28
user____friedbat: that rabbit hole again ?21:28
mefistofelesfriedbat: yes, the macaques study is a famouse one, never made it to peer reviewed journal though, I think21:29
friedbatthe peer review process takes time21:29
friedbatthat's why people are reading preprints21:29
BrainstormNew from r/Italy Live* at 19:25 UTC: /u/pixelcraftables: Vaccino → https://is.gd/hbJ2N421:30
friedbatit has to be submitted to a journal, an editor has to assign it to reviewers, the reviewers must read, analyze and comment, the comments sent back to authors, the authors respond to comments in 2nd submission, those get reviewed again, etc etc 21:31
friedbatby then, covid is over21:31
mefistofelesfriedbat: yes, it varies I know21:31
ArsaneritI was invited to peer review a covid-19 related paper (about reduced air pollution in China measured with satellites)21:31
friedbatso "it's not made it to peer review" can be said about most things21:31
mefistofelesfriedbat: I'm very familiar with that21:31
Arsaneritfriedbat: no, it doesn't need to be over by then21:32
friedbatjust like "the therapeutic hasn't been part of a clinical trial"21:32
mefistofelesbut there are many papers being published really fast now, for covid-1921:32
Arsaneritfriedbat: for the paper I was invited to review, I had 5 days to complete the review, then the authors have 2 weeks to submit their revision, then the reviewers have 3 days for the next round of review21:32
mefistofelesand that one has there weeks now, maybe more than a month21:32
mefistofelesiirc21:32
mefistofelesoh yeah march 1421:32
LjLfriedbat, well, with therapeutics, i'd really be careful, because the way it's turning out, many that "seemed" useful aren't proving useful in actual clinical trial, or are even being shown to be harmful21:32
Arsaneritfriedbat: peer review can be done in a month or less for a fast journal21:32
LjLplacebo effect can be strong, and stronger when doctors are experiencing it and turning it into bias21:32
friedbatLjL: i agree, we do need to be careful21:32
Arsaneritwith only 2 weeks to review it means there won't be the chance to redo the experiments, so in that case the paper would be rejected21:33
mefistofelesI remember the first one with CryoEM structure for RBD and receptor... was really a draft, but made it to Science in a week21:33
friedbati am just saying, if you're only going to accept peer-reviewed papers, you're not going to get much information for a while21:33
LjLagreed21:33
Arsanerityes, the situation necessitates decisions based on unsure information21:33
mefistofelesfriedbat: sure, nobody is saying that, though21:33
LjLbut there are crap preprints i guess, they should each be judged on merits21:33
Arsaneritand there is a risk of major decisions made on incorrect information21:33
friedbatyes, peer review adds another "seal of approval" and we're going to have to do without that. so the SNR is higher.21:34
ArsaneritI'm still confused about Sweden.21:34
friedbatbut that's life21:34
friedbatcovid-19 isn't a patient virus21:34
friedbatit won't wait21:34
friedbatfor us to peer review everything21:34
mefistofelesbut anyways, what give the best reasonable doubt for reinfection is the fact that not all recovered people are not developing antibodies21:34
mefistofelesso of course, raising questions about actual immunity is reasonable21:34
friedbatin 2 years, after all the trials are done and we have tons of data and expirements, we can publish the most beautiful and wonderful peer reviewed articles in JAMA or Nature or whatever.21:35
mefistofeless/not developing/developing21:35
friedbatyes, i heard that too. that not all recovered patients have high titers of antibodies.21:36
ArsaneritIf Sweden can indeed manage without overwhelming its healthcare system does that mean other countries should act more like Sweden (lesser impact on society)?21:36
friedbatArsanerit: a good argument can be made that yes.21:36
mefistofelesfriedbat: some of them don't have at all, according to one study from Shanghai21:36
mefistofeles(preprint :P)21:36
friedbatmefistofeles: i am not too keen on studies out of china21:36
mefistofelesfriedbat: well, those are the most commonly cited for this21:37
friedbati'm aware. but they don't have a free scientific community21:37
ArsaneritBut why is Stockholm so different from Bergamo, New York City, or Guayaquil?  Why isn't it seeing mass graves?21:37
mefistofeleshttps://blogs.sciencemag.org/pipeline/archives/2020/04/08/covid-19-antibody-update-for-april-8 for example that one21:37
friedbatpeople who say the wrong things get disappeared, and ccp censors review all studies21:37
mefistofelesand we all know that guy Derek does a really good job reviewing literature21:37
friedbatso that's even worse than pre-prints21:38
LjLmefistofeles, i'm more worried/scared about the virus never really *going away*, but that might just be me being biased by my own fears...21:38
user____friedbat: you have some references for that?21:38
LjLand yet, there are a few signs21:38
user____that aren't Radio Free Asia 21:38
mefistofelesLjL: I see, I'm actually expecting we'll have to live with this for life21:38
Arsanerityearly corona shot?21:38
mefistofelesactually since that first TWIV podcast I linked months ago21:38
mefistofeleswhere they agreed on that suspicion21:38
LjLmefistofeles, and that doesn't freak you out? luck you21:39
LjLlucky21:39
storgeLjL: i believe your fears are sober and grounded. like mefistofeles i think it's just become an endemic part of life.21:39
Arsaneritbe happy it's not airborne HIV21:39
mefistofeleslol21:39
friedbatif coronavirus doesn't go away, there might be enough money/interest for a universal vaccine21:39
Arsaneritwhat if HIV, SARS-cov-2 and Ebola cross?21:39
LjLwell, endemic like what, endemic like herpes, except that instead of periodically getting cold sore, we'll periodically get life-threatening pneumonias?21:40
LjLbecause that would be... not ideal21:40
storgefriedbat: if a vaccine is even possible21:40
friedbatyes, that's true21:40
mefistofelesdepends, and if a treatment doesn't come first, and many factors21:40
storgeLjL: like the seasonal cold constantly rolling around, but it has a certain level of lethality. 21:40
ArsaneritI hope it's easier to develop a covid vaccine than a HIV/AIDS  vaccine21:40
mefistofelesArsanerit: it should be21:41
friedbatit's an easier virus than hiv, no?21:41
storge"easier"?21:41
friedbatin that it's a more simple entry into cells21:41
LjLmefistofeles, friedbat: anyway i added studies/links to my list without reading them carefully enough yesterday, but, as we were discussing them, there were at least two studies on antibodies linked... one is the chinese one but there was another one indicating higher rates of immunity. i hope i've linked the right one, they are in the "immunology and vaccines" section of the thing21:41
Arsaneritmefistofeles: apparently, although I have zero expertise to understand why21:41
mefistofelessince commony when virus have these "violent" symptoms the vaccine targets are easier to get21:41
storgemefistofeles: can you elaborate on that?21:42
friedbatLjL: is the link https://covid19.specops.network ?21:42
ArsaneritI imagine it may take a bit more than someone on IRC to elaborate on that.  Such as 5 years of medicine studies.21:43
Arsaneritif not 8 years21:43
mefistofelesstorge: not really, just something I read21:43
mefistofelesbut one reason is that they have S proteins21:43
mefistofelesI guess21:43
friedbatwell, all viruses have proteins21:44
friedbatthe point is the S-protein is not mutating in a significant way and is very similar to SARS1 and is also thought to be (though this is not changing) the only method of cell entry21:44
friedbatnow changing*21:44
LjLfriedbat, yeah21:45
friedbatby that i mean, some studies are theorizing that S-spike to ACE2 is not the only way it can infect21:45
friedbatwhich is scary shit21:45
LjLfriedbat, oh damn i did a stupid21:45
LjLlinked the same study twice -.-21:45
oribatinwhiskers: I'm back from supermarket. You have interesting results?!21:45
LjLfriedbat, also the study in question is ALSO chinese anyway, but still, this one https://www.ncbi.nlm.nih.gov/pubmed/3222151921:46
mefistofelesfriedbat: well, of course all virus have proteins, but, still viral *spike* proteins for all?21:46
oribamefistofeles: the pop.dens-data would be interesting for me too...21:47
mefistofelesah right21:47
mefistofelesyes, let me put that here21:48
user____Hemaglutein spikes 21:48
mefistofeleshttps://bpaste.net/TEVQ 21:48
friedbatLjL: i'm quite skeptical of chinese sources and also of the notion that one can recover without antibody titers. maybe "recovery" in these very small-sample chinese studies are false negatives on tests. or bad sero-conversion testing.21:48
mefistofelesoriba: pop density in pp/km²21:48
mefistofelespop*21:48
LjLfriedbat, you may be right, honestly i know too little about the immune system's working to have a valid opinion21:49
friedbatthat one study is 173 patients. in a country of 1+ billion with who knows how many hundreds of thousands of cases, that's the best they can do?21:49
oribamefistofeles: person/km²  (what is pp? pperson?)21:49
mefistofelesoriba: typo for "pop"21:49
oribaok21:49
mefistofelesoriba: but yeah, habitants/km²21:49
friedbatLjL: i'm not saying it can't be true...just that i'm not ready to give it much weight yet. i think we need some other countries to find similar.21:50
oribamefistofeles: nice, have the data ... where did you get it from?21:50
mefistofelesoriba: world bank21:50
tinwhiskersoriba: shortly :-)21:50
LjLfriedbat, well, 173 may be too little compared of what they could be doing, but then, apparently other countries haven't done any preprints on this at all, so :P21:50
oribamefistofeles: nice. scraped? Or just downloaded?21:51
mefistofelesoriba: downloaded and filtered with python21:51
friedbatLjL: yeah, other countries aren't far enough along to do much with recovered patients yet. though i imagine soon.21:51
oribamefistofeles: nice :-)21:51
oribamefistofeles: ok, forget wikipedia ;-)21:51
BrainstormNew from CNBC Health at 19:48 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay21:51
friedbatLjL: i hope it's not true. that would suck.21:52
mefistofelesoriba: I cross-checked some with wikipedia, just to check I wasn't messing it up... it fits 21:52
oribamefistofeles: ok. :-)  But it just goes into my archive... for later use... then I will check it. Thanks anyway.21:52
mefistofelesoriba: I may do some tool to download this automatically from world bank... maybe21:53
mefistofelesI mean, this and other type of data21:53
mefistofelesthey have a pretty decent API, it seems21:53
oribagood to know21:53
friedbatOh this might interest some of you and other like LjL more specifically. some folks in italy are finding covid-19 genetic traces in air pollution particles.21:55
friedbatand they theorize covid-19 could spread over large distances via this air pollution21:56
stinkpotwow21:56
stinkpotthis is something i didn't consider21:56
stinkpothitching a ride on an air pollutant...21:56
friedbathttps://www.medrxiv.org/content/10.1101/2020.04.15.20065995v221:57
oribavirologists say, if the virus dries out, it is no longer able to infect people. So, if it travells with dust, it will be dried out...21:57
stinkpotwell the lipid bilayer can take a few days to destruct via 'drying out'21:57
oribabut add uv-light21:58
stinkpotdestruct => disintegrate21:58
mefistofelesfriedbat: interesting22:01
BrainstormNew from BBC Health at 19:59 UTC: (news): Coronavirus test online slots booked up within hour of site reopening → https://is.gd/4LjVjP22:06
tinwhiskersoriba: well, I've done it but it's utterly meaningless at this point :-)22:06
mefistofelestinwhiskers: heh, well, negative results are results22:09
oribatinwhiskers: ah ok. Good to know :-) Thanks for your effort!22:10
oribatinwhiskers: now we know more ... a little bid ;-)22:11
tinwhiskersoriba: well, all is not lost... pm?22:11
BrainstormNew from Ars Technica at 20:00 UTC: Cars: What does COVID-19 mean for car design? We ask Jaguar’s Julian Thomson → https://is.gd/qCzGVg22:13
oribaAerosol Filtration Efficiency of Common Fabrics Used in Respiratory Cloth Masks https://pubs.acs.org/doi/10.1021/acsnano.0c0325222:14
oribatinwhiskers: pm, if you wish22:15
mefistofelesoh sad... they are seeing more perforated appendices from fear of going to hospitals22:18
l0ndonerhospital is the last place I would want to be right now22:18
l0ndoner60% more chance of catching cov-19 than staying and dieing at home 22:18
tinwhiskersoriba: well, if you take a look as it stands using 1/density as a scaling factor for the time series data it's just very uninteresting. http://offloop.net/covid19/dev.pl (turn on "by population" - the labels have not been changed so make no sense). If you can think of a way of making the density a useful scaling factor maybe it's useful.22:18
mefistofelesl0ndoner: yes, but covid is not that fatal, staying at home with an appendicitis is22:19
mefistofelesor a stroke or whatever22:19
stinkpotmefistofeles++22:19
l0ndonerpfffft the NHS told us all to stay away.... Now moaning that we did22:20
l0ndonergo figure22:20
BrainstormUpdates for US: +6598 cases (now 952995), +290 deaths (now 53745) since an hour ago — Massachusetts, US: +2379 cases (now 53348), +174 deaths (now 2730) since 21 hours ago — Illinois, US: +2119 cases (now 41777), +79 deaths (now 1874) since a day ago22:21
mefistofelesah, nice, steroids help apparently... and keep people out of ventilators22:22
l0ndonerchewing on raw ginger helps22:22
tinwhiskersl0ndoner: ??22:23
tinwhiskerslet's just be clear that there is ZERO evidence for that22:23
l0ndonerthat stuff clears the airways like no ones business22:23
tinwhiskersopening up your sinuses is not clearing your lungs22:24
oribatinwhiskers: I don't know what you mean ... the rank of countries does change. So it has influence. Maybe start with a smaller selection of countries might make sense? Or grouping countries by pop.dens.?  Maybe cluster analysis would be fitting better? hmhh not sure22:24
l0ndonerhad a slight tickly cough... Chewed some ginger boom it went22:24
tinwhiskersoriba: Yeah, well I'll leave it there for you to explore and if you see if you can find any meaning in it22:25
tinwhiskersoriba: or let me know if you need a change made22:25
oribatinwhiskers: I removed the two with moset cases before plaing around.22:25
tinwhiskersl0ndoner: don't get me wrong. I actually eat ginger to aid reflux and I'm moderately confident it helps so I'm not entirely scoffing at herbal remedies but... ginger for covid.... that's misinformation.22:26
oribatinwhiskers: reload the url (dev.pl) then remove USA then remove Spain. then click on "by population". Canada jumps to 1st place!22:28
l0ndonertinwhiskers: on a serious point.... More people seem to be congregating here now... I.E roads are busier and people don't seem to be social distancing as much as before I.E earlier in month and yet the stats and the R seem to be tailing offeBut the stats are declining 22:28
oribatinwhiskers: would need more investigation if that makes sense. But if it would, his would mean canada performs bad regarding pop.density.22:29
tinwhiskersoriba: or my scaling is backwards?22:29
tinwhiskersor something else :-)22:29
oribatinwhiskers: don't know.22:29
oribahehe22:29
oribasomething else is a good answer :-)22:30
oribasomething has happened - we know it for sure22:30
oribait was the one reason or the other22:30
oribaor something else22:30
oribawe know that for sure!22:30
l0ndonerI think Swedens model was right and everyone over reacted22:31
tinwhiskersoriba: well, I've copied it to http://offloop.net/covid19/density.pl (before it gets overwritten with some other change) and it'll stay there for the foreseeable future. If you have any ideas let me know :-)22:31
oribatinwhiskers: or maybe it just looks unusual and we expect to see the usual. Maybe so it's better than we think?22:31
tinwhiskersneed to sit down and do some numbers in a spreadsheet to see what makes sense.22:32
oribatinwhiskers: ok. I should start my own investigation. But I have invested much too much time into the pandemy topic, that other things start to drag behind.22:32
tinwhiskersheh. ok. Cheers22:33
oribaneed to go learn things... should leave irc for now, otherwise I'm distracted too much...22:34
oribaso until next time.22:34
tinwhiskerso/22:34
BrainstormNew from The Guardian at 20:24 UTC: Coronavirus outbreak: Coronavirus US live: 'What you're doing is saving lives': Cuomo calls quarantining this generation's challenge → https://is.gd/w1kAAn22:34
mefistofelesah interesting, there are some negative pressure ventilators, old and deprecated, but apparently the new modern ones with positive pressure are actually producing more inflammation... but the old ones are technically harder to use22:39
tinwhiskersmefistofeles: yeah, I heard mention that the old iron lung was a better approach here22:40
mefistofelestinwhiskers: yes, indeed... but it gives less access so it depends22:41
friedbatmefistofeles: some places are using vents less frequently. preferring to use o2 masks rather than invasive vents which seem to be causing both alveolar damage and increased inflammation22:41
tinwhiskersmmm22:41
mefistofelesI wonder how many people could've been saved by not putting them in ventilators too soon, which is a honest mistake of course22:41
friedbatsome places did that on purpose22:41
friedbatthey thought early intubation helped increase survival chances22:41
tinwhiskersoops22:42
BrainstormNew from CNBC Health at 20:38 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay22:42
mefistofelesfriedbat: yeah, but that's honest mistake22:42
mefistofelesthinking it would benefit the patients22:42
tinwhiskerswe're sure going to learn a lot from this anyway22:42
tinwhiskersI hope we retain some of the learnings22:42
mefistofelestinwhiskers: save ##covid-19 logs!!22:43
mefistofelesxD22:43
mefistofelesin magnetic tape22:43
tinwhiskersobviously some are specific to this virus and may not be very useful but there's a whole lot of general stuff too22:43
tinwhiskersmefistofeles: lol22:43
friedbata lot of things were done in a reactive manner. nationwide shutdowns when people were suggesting 3-5% overall fatality rates, vents when the pulmonary distress might be secondary, etc.22:44
friedbatnow we know the fatality rate is closer to 0.5% than to 5%22:44
LjLi was wondering a bit about that earlier22:45
friedbatand we also know that vents aren't necessarily the best approach22:45
LjLwe do see to have early evidence from these antibody studies that the death rate is not SO high22:45
tinwhiskersI'm hesitant to agree to the 0.5 but it's not far off22:45
LjLhowever when i hear about high-profile cases, and by that i don't mean "rich people" but like, "patient one" in italy22:45
LjLhis father died of COVID22:45
LjLand he definitely nearly died22:46
friedbatLjL: yeah, the numbers suggest an order of magnitude difference from what experts believed in february22:46
LjLthere seem to be entire families that don't just get infected as you would expect from living together. they all DIE22:46
tinwhiskersyeah22:46
LjLit's anecdotal but i find it hard to reconcile22:46
friedbatLjL: that might be a genetic issue22:46
dinkoarun<l0ndoner "I think Swedens model was right "> Exactly. There is no escaping this virus. All we are doing is trying to slow it down at the expense of the economy. Better to face it head on and then move on.22:46
friedbatthey might all be obese, or asthmatic, or all type A blood, or all live in a highly pollutated area, etc.22:46
friedbatsome traits are familial and others are geographic. a family unit checks both those boxes.22:47
mefistofelesfriedbat: yes, my bet is on 0.422:47
LjLwell if simply being one of these things makes you very likely to die, then the death rate would not be 0.5%22:47
tinwhiskersor just got unlucky due to chance when dealing with vast numbers22:47
friedbatmefistofeles: i wouldn't be surprised by 0.4%. i expect it's probably 3-8 times more deadly than flu which is about 0.1%22:48
friedbatso i would expect something in 0.3% to 0.8% range22:48
mefistofelesfriedbat: indeed22:48
LjLi don't know, i'd like to see data on the families of patients who died22:48
tinwhiskersfriedbat: seems fair22:48
LjLbut that's most likely not publicly available for reasons some of of which are obvious22:48
friedbatmefistofeles / tinwhiskers, so far all the antibody studies (except that crazy stanford one) put it in the 0.4% vicinity (give or take)22:49
mefistofelesfriedbat: exactly, yes22:49
LjLi added one other article yesterday22:49
LjLyou will find it opinionated22:49
mefistofelesI find opinionated that you add things without asking22:50
mefistofeles:P22:50
LjLif i linked right to *at least* this one22:50
tinwhiskersyes, but the antibody tests are a little suspect at this stage (notwithstanding the crazy ones)22:50
LjLmefistofeles, ?22:50
LjLhttps://www.sciencemag.org/news/2020/04/antibody-surveys-suggesting-vast-undercount-coronavirus-infections-may-be-unreliable22:50
tinwhiskersfriedbat: but, yeah, your range stacks up to me22:50
LjLtinwhiskers, this article details its finding them suspect22:51
LjLfwiw22:51
l0ndonerSo we screwed the worlds economy for a death rate that is far less than the FLU22:51
mefistofelesLjL: just joking, though I don't really know how things get added there, if it's just your personal opinion what counts ir if there's anything else22:51
tinwhiskersLjL: yeah, that's referring to the Santa Cruz and NY studies, which are to be ignored22:52
LjLtinwhiskers, NY is that bad?22:52
tinwhiskersLjL: but yes, that's the reason I'm hesitant22:52
LjLmefistofeles, pretty much my personal opinion tbh, and also whether or not i remember to add something when i see it and still find it later, and i often ask yuriwho22:52
mefistofelesok22:53
friedbati wasn't aware the ny study was being heavily doubted22:53
tinwhiskersLjL: not *as* bad. We've got a few studies from other countries that tend to put it squarely below 1% anyway22:53
mefistofelesfriedbat: NY? where?22:54
friedbatthe stanford one seems like a bunch of bad things put together. possibly junky tests, selection bias, and then some weird agenda of one of the lead researchers22:54
friedbatmefistofeles: tinwhiskers said the ny serology study was bad22:54
nixonixand that new york antibody survey on top of those22:54
mefistofelesl0ndoner[m]: no, it's larger than that of the FLU, even possibly 10x larger22:55
friedbatalso, the issue with the lockdowns wasn't just because of a higher mortality rate but because of the high infectioneness. the worry was that suddenly you'd have way more very sick people than hospital beds.22:55
mefistofelesI have not seen results from that NY test, though22:56
friedbattoo many sick all at once, in other words22:56
friedbatmefistofeles: i think they found overall like 13% seroprevalence22:56
BrainstormNew from r/Italy Live* at 20:54 UTC: /u/pixelcraftables: A domani → https://is.gd/J81ZJj22:56
friedbatbut i might be mis-remembering.22:56
tinwhiskersErm, I meant Santa Clara22:57
friedbatoh yeah, santa clara looks like crap22:57
friedbatthat's the stanford folks22:57
mefistofelesah yeah, thee Stanford/Santa Clara one is really half-baked to say the least22:57
mefistofeles*the22:57
mefistofelesI linked this earlier, but just in case https://statmodeling.stat.columbia.edu/2020/04/19/fatal-flaws-in-stanford-study-of-coronavirus-prevalence/22:58
tinwhiskersthat one was hilarious22:58
friedbati think one thing we have proven (once again) is that we're really bad with the unknown. we get into fear mode and make poor decisions.22:59
friedbatwe being humans.22:59
friedbatand even people like epidemiologists, who spend their entire lives using logic and reason, end up making fear-based policy calls.23:00
tinwhiskersindeed23:00
tinwhiskersthat's why I dislike the blame politics so much. mistakes don't need to be punished.23:00
tinwhiskersyou can still poke fun at the really silly things that happen though23:01
friedbati agree. honest mistakes should be learned from not punished. intentional negligence should be held to account though.23:01
tinwhiskersyeah23:02
BrainstormNew from CNBC Health at 20:58 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay23:03
CovBotI now have regional case data on the UK again thanks to changes contributed by Rob Hallam. Plus this now includes not just England but Scotland, Wales and Northern Ireland!23:21
BrainstormNew from The Guardian at 21:11 UTC: Coronavirus live news: global death toll passes 200,000: Greece prepares to end lockdown; Bill Gates vows to fund vaccine production; Australia and New Zealand mark Anzac Day from driveways → https://is.gd/l1n5s223:24
BrainstormNew from CNBC Health at 21:26 UTC: (news): Coronavirus live updates: Global deaths cross 200,000, US beaches reopen, NY expands testing → https://is.gd/fxCyay23:32
AtqueHey. Can everyone pray, so God intervenes and stops the COVID-19 pandemic?23:33
mefistofelesAtque: heh23:34
BrainstormNew from The Guardian at 21:46 UTC: Coronavirus outbreak: Coronavirus US live: 'What you're doing is saving lives': Cuomo calls quarantining this generation's challenge → https://is.gd/w1kAAn23:53

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