libera/##covid-19/ Tuesday, 2020-11-10

LjLmaybe there are ways that sociologists and *cough* PR people (even though i kind of detest PR) could think of00:04
LjLbut i'm not one of them, not nearly clever enough, so i dunno00:04
rpifantheres lots we could do00:04
rpifanbut the govt is lazy and poor00:04
BrainstormUpdates for New Mexico, US: +1408 cases (now 56289), +12 deaths (now 1130) since 22 hours ago — Mayotte: +265 cases (now 4815), +1 deaths (now 46) since 5 days ago — US: +131070 cases (now 10.4 million), +631 deaths (now 244344) since a day ago00:05
DocScrutinizer05>>some people are going to read that as "pandemic over."<< pretty much anticipated effect, I hope your government is properly covering this aspect and dealing with it in public statements00:17
DocScrutinizer05the pandemic *might* be over no earlier than 202200:17
LjLbut telling people *that* is also demoralizing and can result in them dropping protection measures00:18
LjLit's tricky00:18
DocScrutinizer05simple exercise for the interested reader: calculate duration to vaccinate 70% of your people in vaccination centers - since most likely the vaccine can't get handled by your personal medical doctor00:19
BrainstormUpdates for Colorado, US: +3553 cases (now 134537), +14 deaths (now 2408) since a day ago — US: +134975 cases (now 10.4 million), +677 deaths (now 244390) since a day ago00:20
DocScrutinizer05keep in mind a vaccine is no therapy00:22
DocScrutinizer05just for reference: Biontex&Pfizer hope to ship 50 million this year and 650 million whole next year. *Globally*00:27
LjLuh, Derek Lowe wrote 1.3 billion00:33
BrainstormNew from Medical Xpress: Diseases, Conditions, Syndromes: Severe COVID-19 infection rare in newborns → https://is.gd/RqKce000:33
BrainstormUpdates for Fr. Polynesia: +685 cases (now 10680), +10 deaths (now 49) since 2 days ago00:35
de-factoafaik mRNA is very efficient, e.g. small doses already have big effect, but its also unstable so it needs cold storage supply chain00:39
de-factonot sure how production itself scales00:39
BrainstormUpdates for Canada: +1219 cases (now 268735) since an hour ago — US: +457 cases (now 10.4 million), +7 deaths (now 244399) since 16 minutes ago00:50
DocScrutinizer05LjL: >>1.3 billion<< one person = 2 shots00:57
LjLoh, right00:57
DocScrutinizer05now, in 3 weeks, and in 4 weeks you're done00:57
DocScrutinizer05so even optimistically, we may see no more rgan 30 million vaccinations this year in whole Europe, 20 in US00:59
DocScrutinizer05than*00:59
DocScrutinizer05I anticipated the >>now we got the vaccine. So the heck WHEN will we stop to wear masks, this week or next???<< a few months ago already, and expect to hear that shit this week or next :-/01:01
DocScrutinizer05LjL: on the bright side, things *will* change next spring the latest. Keep sane and take care of yourself until then, pal! :-)01:03
LjLthat ship has sailed01:05
BrainstormUpdates for US: +2765 cases (now 10.4 million), +14 deaths (now 244406) since 32 minutes ago01:06
BrainstormUpdates for US: +4383 cases (now 10.4 million), +27 deaths (now 244419) since 47 minutes ago01:21
LjLCalifornia publishes updates just way too often01:23
LjL(also it's back to minutes because i messed up the code and deleted the last day's worth of data)01:23
BrainstormNew from r/WorldNews: worldnews: Dr. Anthony Fauci reacts to Pfizer's coronavirus vaccine announcement - "It's extraordinary, it really is a big deal". → https://is.gd/j7SQ0s01:29
BrainstormUpdates for US: +7508 cases (now 10.4 million), +32 deaths (now 244424) since an hour ago01:36
BrainstormNew from Gazzetta Ufficiale italiana: DECRETO-LEGGE 9 novembre 2020, n.149: Ulteriori misure urgenti in materia di tutela della salute,  sostegnoai lavoratori e alle  imprese  e  giustizia,  connesse  all'emergenzaepidemiologica da COVID-19. (20G00170) → https://is.gd/dEI7Nq01:38
BrainstormUpdates for US: +8017 cases (now 10.4 million) since an hour ago01:50
LjLsurprise law?01:51
LjLunimportant mini-law01:52
DocScrutinizer05%tr  DECRETO-LEGGE 9 novembre 2020, n.149: Ulteriori misure urgenti in materia di tutela della salute,  sostegnoai lavoratori e alle  imprese  e  giustizia,  connesse  all'emergenzaepidemiologica da COVID-1901:53
BrainstormDocScrutinizer05, English to English: DECRETO-LEGGE 9 novembre 2020, n.149: Ulteriori misure urgenti in materia di tutela della salute, sostegnoai lavoratori e alle imprese e giustizia, connesse all'emergenzaepidemiologica da COVID-19 (Google)01:53
DocScrutinizer05%tr  <it DECRETO-LEGGE 9 novembre 2020, n.149: Ulteriori misure urgenti in materia di tutela della salute,  sostegnoai lavoratori e alle  imprese  e  giustizia,  connesse  all'emergenzaepidemiologica da COVID-1901:54
BrainstormDocScrutinizer05, Italian to English: DECREE-LAW of 9 November 2020, n.149: Further urgent measures in the field of health protection, support for workers and businesses and justice, related to the covid-19 environmental emergency (MyMemory) [... want %more?]01:54
DocScrutinizer05LjL:  surprise law? 01:55
DocScrutinizer05why surprise?01:55
LjLDocScrutinizer05, just because i'm used to Gazzetta Ufficiale popping up after a pompous speech by the PM these days01:56
LjLbut since i'm not aware of any special law being passed, i was surprised to see it. but it's just a small amendment to existing COVID laws01:56
DocScrutinizer05so it wasn't announced ahead of time?01:57
BrainstormNew from "Cluster 5" on Wikipedia: Novem Linguae: Novem Linguae: "Cluster 5 coronavirus infections have been reported in 7 countries as of November 9, 2020. These countries are..." + 2 citations → https://is.gd/74bzDF01:57
DocScrutinizer05aaah01:57
de-factough @ cluster 502:01
DocScrutinizer05unrelated: you ever noticed how utterly useless "running doubling time" turns to be later on in an epidemic?02:01
LjLtinwhiskers has02:03
DocScrutinizer05((clusterfsck))  >>These countries are Denmark, Sweden, Israel, the United States, Italy, Spain, and the Netherlands<<02:03
DocScrutinizer05indeed UGH02:03
de-factothats a weird sentence @ wikipedia02:04
de-factonot all CoVs are Cluster 5, so its unclear if they mean mutations or associate the generic term "cluster 5" with minks02:05
BrainstormUpdates for Guam: +396 cases (now 5473), +5 deaths (now 90) since a day ago — France: +10315 cases (now 1.8 million) since 5 hours ago — Somaliland: +111 cases (now 1188), +1 deaths (now 37) since 14 days ago — US: +10003 cases (now 10.4 million), +56 deaths (now 244448) since an hour ago02:05
de-factoi want to see the sources02:05
BrainstormNew from "Cluster 5" on Wikipedia: Novem Linguae: add link: add link ← Previous revision Revision as of 01:03, 10 November 2020 Line 2: Line 2: "'''Cluster 5'''" is an outbreak of a mutated variant of the [[SARS-CoV-2]] virus, which may lead to [[COVID-19]]. It was discovered in [[Northern Jutland]], [[Denmark]], and is believed to have been spread [... want %more?] → https://is.gd/74bzDF02:06
DocScrutinizer05"6 countries find coronavirus at mink farms; fears mutation could hinder vaccine". The Times of Israel. 8 November 2020. Retrieved 9 November 2020.02:07
DocScrutinizer05"Israelis may be infected with new coronavirus strain from Denmark minks". The Jerusalem Post. 9 November 2020. Retrieved 9 November 2020.02:07
LjLyes02:07
LjLi already changed the article02:07
LjLeditor was stupid02:07
de-factohere they say "Three Israelis who returned from Denmark and were confirmed as infected with the novel coronavirus may have been infected with the new strain discovered among minks in the country recently, according to KAN news." https://www.jpost.com/israel-news/israelis-may-be-infected-with-new-coronavirus-strain-from-denmark-minks-64851302:13
de-factoso its their suspicion only that the possibility MAY be there hence they do sequencing02:13
LjLi take "may have been" as "it's possible since they came from denmark"02:14
LjLyes they MAY do sequencing if they are smart :P02:14
BrainstormNew from "Cluster 5" on Wikipedia: LjL: LjL: Add quotes for exact words on mink infections in other countries (not Clsuter 5, at least not as far as we know) → https://is.gd/74bzDF02:16
de-factoyeah so its false alarm at least from that article until they are showing the sequences 02:16
de-factoits good they check for it though02:16
BrainstormUpdates for US: +10066 cases (now 10.4 million) since an hour ago02:20
DocScrutinizer05it's good you guys check wikipedia :-)02:23
de-factoLjL is omnipresent :)02:23
DocScrutinizer05btw is it smart to translate a term that looks exactly same after translation? >>Danish State Serum Institute (SSI) has designated these as clusters 1–5 (Danish: cluster 1-5)<<02:26
de-factohuh? what do you mean by that?02:27
DocScrutinizer05clusters 1–5 (Danish: cluster 1-5)02:27
DocScrutinizer05maybe I'm blind or sth, but seems to me cluster 5 is danish AND english02:28
de-factowell why not? to search including the danish original term?02:29
BrainstormUpdates for US: +10823 cases (now 10.4 million) since 2 hours ago02:36
LjLDocScrutinizer05, it's because the plural in danish remains "cluster" instead of "clusters"02:37
LjLit's a bit of an... OCD? thing to specify02:37
LjLbut i'm not sure i want to get into an edit war over *that* :P02:37
CoronaBot04/r/coronavirus: Live updates: Fauci calls Pfizer vaccine results ‘extraordinary’ as U.S. cases approach 10 million (10017 votes) | https://www.washingtonpost.com/nation/2020/11/09/coronavirus-covid-live-updates-us/ | https://redd.it/jr1pg902:38
DocScrutinizer05LjL: I'd not expect plural in a "name" even in english. In danish those are clearly names and an enumeration of named items shouldn't use plural for the name. My 2 cent02:42
LjLwell i don't know in danish, but in english "clusters 1-5" is correct while "cluster 1-5" would be questionable02:43
DocScrutinizer05cluster-1 to cluster-5 would be absolutely correct in my book02:43
LjLwith no hyphen in english, but yeah you could write that02:44
LjLanyway i've already corrected the big factual error in that article today, i'm going to leave the linguistic quibbles alone :P02:44
DocScrutinizer05it's a mix up of use of a generic noun "cluster, plural clusters" and an name cluster-1 ... cluster-502:45
LjLplus "cluster 1-5" is a direct quote from the source, which is a source in danish02:45
LjLit's not a mix up02:45
LjLit's perfectly correct english02:45
DocScrutinizer05well, I stumbled over it, maybe it's my poor english comprehension02:46
LjL"Xs n1 to n2" is a standard English construct. it doesn't need to make "logical" sense, languages don't work like that02:47
BrainstormUpdates for US: +10946 cases (now 10.4 million) since 2 hours ago02:51
DocScrutinizer05the catch is this is suggesting that "Cluster 5" was derived from the danish plural  form of english "clusters" which it isn't. There's simply no reason to explain aka "translate english >>clusters number1 to number5<< to danish >>cluster[pl.] #1-#5 << since the name got derived from the singular of course02:52
BrainstormNew from The Indian Express: World: Brazil suspends trials of China’s Sinovac COVID-19 vaccine due to ‘adverse effect’ → https://is.gd/pzT5OO02:53
BrainstormNew from CNBC Health: (news): The coronavirus pandemic ‘is about to explode’ before therapeutic counterattack, Dr. Scott Gottlieb says → https://is.gd/D5fLn203:03
de-factooh someone did exponentials ^^03:03
LjLoh another trial suspension03:04
de-factosinuvac is another attenuated original right?03:05
LjLinactivated03:06
DocScrutinizer05chinese?03:07
de-facto"Brazil’s health regulator Anvisa said on Monday it had suspended clinical trials for China’s Sinovac coronavirus vaccine, due to a “severe adverse effect” that took place on Oct. 29."03:07
de-facto"Anvisa did not provide more details, such as whether the incident took place in Brazil – where trials are being conducted – or in another country."03:07
de-facto"It also did not say why news of the October event was being communicated only now."03:07
de-factooh right of course inactivated03:07
de-factohttps://covidvax.org/covid19-vaccine/Sinovac/Inactivated-alum-Sinovac-Instituto-Butatan03:08
tinwhiskersI think attenuated is just another word for inactivated?03:08
LjLtinwhiskers, no03:08
tinwhiskersAh. Ok03:08
de-factonope attenuated is "functional" but weakened beyond a point that it is not dangerous anymore03:08
LjLtinwhiskers, attenuated can still replicate, just supposedly not enough for a full-blown infection or being contagious03:08
tinwhiskersOk03:09
de-factoinactivated is non-functional in a sense of replication afaik03:09
DocScrutinizer05>>...communicated only now<< seems pretty consistent for chinese stuff03:09
LjLtinwhiskers, they sometimes go wrong. today, the leading cause of polio is the attenuated polio vaccine03:09
de-factomy bad, i am a bit tired already, good catch LjL 03:09
LjLDocScrutinizer05, it was up to Brazil to communicate it i think...03:09
DocScrutinizer05oooh03:09
LjLthe vaccine is Chinese but in Brazil the oversight is by the Brazilian agencies03:10
de-factodo they use adjuvants in those inactivated vaccines?03:11
de-factoDynavax’s CpG 1018,?03:12
LjLi don't know03:14
LjLit's a bit annoying how covidvax doesn't list the vaccine *name* and the vaccine *type* separately...03:14
LjLso if it has a unique name, they use, otherwise the "name" may just be "Inactivated"03:14
LjLde-facto, it says "Inactivated + alum" for Sinovac so that looks like an adjuvant to me i guess03:15
de-facto%title https://www.biopharma-reporter.com/Article/2020/08/17/Gates-Foundation-gives-Dynavax-COVID-19-grant-to-scale-up-adjuvant-production03:15
Brainstormde-facto: From www.biopharma-reporter.com: Gates Foundation gives Dynavax COVID-19 grant to scale up adjuvant production03:15
de-factonot sure if thats contained in there though03:16
LjL"Several insoluble aluminium salts are used as adjuvants in human and animal vaccines, but the term ‘alum’ only applies to aluminium potassium sulphate" (from a random paper)03:16
MikeJoel!cases US03:16
CovBotIn United States there have been a total of 10,421,956 cases as of 2020-11-10 01:58:00 UTC. Of these 3,624,898 (34.8%) are still sick or may have recovered without being recorded, 6,552,610 (62.9%) have definitely recovered and 244,448 (2.3%) have died.03:16
LjLde-facto, it looks like there are two Sinovac vaccines. really just one, but in Brazil (and China?) the adjuvant is alum, while in the US they have this partnership so the adjuvant is called CpG 101803:17
de-factoso alum in Brazil trial then?03:18
BrainstormUpdates for France: +15353 cases (now 1.8 million) since 7 hours ago — Netherlands: +1515 cases (now 416947), +25 deaths (now 8068) since 11 hours ago — Canada: +1704 cases (now 269220), +12 deaths (now 10579) since 3 hours ago03:20
LjLde-facto, i think so03:21
LjLde-facto, i found another list https://ronreiter.github.io/covid-19-vaccine-tracker/ with "source" https://github.com/ronreiter/covid-19-vaccine-tracker (really a spreadsheet)03:21
LjLi kinda want to grab covidvax data and use it in Brainstorm but scraping is boooooring03:22
MikeJoelhmm 244,448 in 10 months. 2018-2019 (6 months) Flu season - 176,590 deaths due to Flu and Pneumonia (a flu complication). That would mean about 29,431 deaths per month... compared to covid at 24 deaths per month. And we are supposed to be terrified of covid? odd03:22
LjLare you even in good faith03:23
MikeJoelis my math wrong?03:23
MikeJoeloh sorry - 24,444 deaths a month - thought it sounded odd... still a bit lower03:24
LjLand also03:24
LjL"CDC estimates that influenza was associated with more than 35.5 million illnesses, more than 16.5 million medical visits, 490,600 hospitalizations, and 34,200 deaths during the 2018–2019 influenza season."03:24
MikeJoelstrange the cdc is where these numbers come from03:25
MikeJoel176,59003:25
LjLwell maybe they are worldwide?03:26
MikeJoelalso if you consider 244,448 - 176,590 = 67,858 yet it covid 4 more months03:26
LjLsorry what are you comparing? i don't follow03:28
MikeJoelhmm? 176,590 deaths in the entire world? I don't think so03:28
LjLlook i don't know which CDC you took that number from but i took it from the American CDC, namely here: https://www.cdc.gov/flu/about/burden/2018-2019.html03:28
LjLso you may want to talk to the other CDC03:28
LjLalso, if your number includes pneumonia for *any* reason (which isn't clear from your description), then it's silly: pneumonia can be a flu complication but it can also arise for a number of other reasons that can't logically be summed up together03:29
MikeJoelj/s03:30
LjLbut also these non-comparable numbers are a distraction. the problem with COVID is a much higher proportion of patients need to end up in hospital to survive decently, *and* the spikes are being much worse than flu03:30
MikeJoelcovid isn't just someone dying from being sick with covid - it includes a lot more than that03:30
LjLsure, teach us03:31
MikeJoelhmm? In America it is like 99% survival if your below like 7003:31
LjLyou're*03:31
MikeJoelor 6003:31
MikeJoelwhatever03:31
LjLand also it's good that you care only about those who are less than 60 "or whatever"03:31
LjLyou are quieted for being a scummy person03:31
LjLi'll unquiet you later if you want to stay but i'd prefer if you didn't03:31
LjLanyway the channel topic has information on the difference between COVID and influenza which you can comment on, if you take the time to read it instead of joining, calling the bot immediately, then bringing up questionable numbers that are not comparable with other numbers03:34
LjLstop staring everyone, yes i'm nervous03:42
tinwhiskersLjL: he failed to consider a whole bunch of things, like the extraordinary measures we've taken to get it as low as it is as well. 03:44
tinwhiskersno point in catering to that bullshit.03:44
de-facto%title https://www.medrxiv.org/content/10.1101/2020.07.23.20160895v7 log10(IFR) = -3.27 + 0.0524 * age = Exp[ Log[2] age / 5.75] / 168203:44
LjLtinwhiskers, to be fair, he was focusing on the US, where "extraordinary measures" were... *cough*arguably taken03:44
Brainstormde-facto: From www.medrxiv.org: Assessing the Age Specificity of Infection Fatality Rates for COVID-19: Systematic Review, Meta-Analysis, and Public Policy Implications | medRxiv03:44
tinwhiskersoh. err. yeah... even there03:45
tinwhiskershalf the people there are wearing masks and being careful, which is not something they've done before with flu.03:45
LjLtinwhiskers, but still he was coming up with a number for flu that i really don't know where he got. if that really is flu + any pneumonia, then why don't we also count cancer and heart attack deaths, and say "hey they're more than COVID, so why do we worry about COVID?"03:45
LjLand at first he made the "innocent mistake" of saying 24 deaths per month instead of 24444 deaths per month03:46
tinwhiskersyeah. self-deluded, ignorant or plain dishonest (I'm guessing the latter).03:46
LjLi'd almost believe it's a genuine mistake if my logs didn't have an AKICK for him in ##coronavirus dating back from March03:46
tinwhiskersclearly open to learning03:46
de-factoWith "log10(IFR) = -3.27 + 0.0524 * age" from above paper hence IFR(age) = 100% Exp[ Log[2] age / 5.75] / 1682 it gives for age = {60, 65, 70, 75, 80, 85, 90} the IFR = {0.82%, 1.50%, 2.75%, 5.02%, 9.17%, 16.76, 30.61%}03:53
de-factoHenceIFR[84.96 years] = 16.6% or Russian roulette03:54
BrainstormNew from r/WorldNews: worldnews: The trial of Chinese Covid-19 vaccine Coronavac has been halted by Brazil, citing a serious adverse event. China has already given the vaccine to people → https://is.gd/Q72nx504:17
LjLso is it called Sinovac or Coronavac04:27
LjLHALT THE TRIAL! THE NAME IS UNCLEAR!04:27
LjL%cases florida04:33
BrainstormLjL: In Florida, US, there have been 847821 confirmed cases (4.2% of the population) and 17179 deaths (2.0% of cases) as of 5 hours ago. 4.1 million tests were performed (20.4% positive). See https://offloop.net/covid19/?default=US for time series data.04:33
LjL4.2% wow04:33
LjLbut soon that will be nothing much compared to europe :(04:33
LjLand 20% tests positive so likely many more cases04:34
ryoumaa05:00
Skunnyb05:00
de-factoc05:02
de-facto%title https://en.wikipedia.org/wiki/CoronaVac05:02
Brainstormde-facto: From en.wikipedia.org: CoronaVac - Wikipedia05:02
BrainstormNew from r/WorldNews: worldnews: New coronavirus lockdown in Greece requires people to text authorities before leaving home → https://is.gd/1jUNS105:03
MikeJoelwondering who the freenode op is in here?05:03
the-wesis there some reason to suspect there is one?05:04
MikeJoelwill the freenode phsyOps please stand up?05:04
MikeJoelthey are everywhere from what i see05:04
MikeJoelFuchs is one05:05
the-westomaw is one05:05
cmpx[m]<LjL "4.2% wow"> I wouldn't trust Florida numbers, they are likely higher than reported.05:06
LjLyeah, okay, but that's already high to begin with05:06
LjLMikeJoel, freenode staff don't manage this channel, channel ops do. i'm a channel op. hi.05:06
DocScrutinizer05oh, de-facto: I added R_eff based on foldedphase to the long term chart in http://reisenweber.net/et_al/covid/covid19_statistics.htm05:07
MikeJoelLjL: yes, but it turns out freenode has people going around joining channels and spying on what they talk about.05:07
LjLthat's not the way i would put it05:07
MikeJoelif they don't like it they warn - then close05:07
cmpx[m]I'm just saying, they are deniers, and have been for some time. I would guess that they are one of if not the worst of the US states, 05:07
LjLbut anyway i'm sure they adore being highlighted randomly05:07
DocScrutinizer05MikeJoel: huh?05:09
jesswhere's my tracking device05:10
de-factoDocScrutinizer05, neat, i wonder how that foldedphase behaves for real peaks, e.g. around the Tönnies peak05:10
LjLjess, where's your freenode staff clo- oh, okay.05:10
jessrekt05:10
de-factobecause it should target periodicity more than peaks05:10
DocScrutinizer05LjL: I forgot the date. just look it up then check that date in first chart?05:11
the-wesif I was an IRCop, step 1 would be to disable notification on mentions05:11
DocScrutinizer05de-facto: ^^^05:11
DocScrutinizer05de-facto: actually you did wonder about that a few days ago already (I did too) that's why I added it to first chart05:12
BrainstormNew from The Indian Express: World: G20 countries still backing fossil fuels through COVID-19 response → https://is.gd/Lyg7MF05:12
de-factomaybe around 2020-06-18 or such?05:13
jessif i was an ircop, i'd use it to find people to hug05:13
LjLif i was an ircop, i'd have "freenode staff" on highlight05:13
de-factowow how tiny it looks already in comparison to the recent huge peak05:13
LjLbut since i'm just LjL, i'll slap everyone who says "if i was" instead of "if i were"05:14
ketasjess: missing a hug?05:14
de-factoi really hope Reff is going down for real and not only due to changing testing strategy or such05:14
LjLthat thing about Greeks being required to send an SMS to leave home weirded me out a bit, but then towards the end of the article it says they can carry a form for the same purpose if they can't (or won't?) text, so i guess it's just like in Italy except with texting being a potentially easier option05:15
jessketas: always!05:16
DocScrutinizer05RKI claimed a 0.7some a few days ago. Though their R is quite jerky, it seems to support my observed trend05:16
ketasconstant lack of human contact05:16
MikeJoelrekk is one?05:17
tinwhiskersMikeJoel: you're waaay off topic fuming about another channel. Not here please.05:17
de-factoDocScrutinizer05, the problem is that testing cap is the current limit so cases will drop automatically05:18
MikeJoelanother channel?05:18
ketas##hugs05:18
tinwhiskersMikeJoel: drop it. It's not on topic for this channel.05:19
jessi can help you with that05:19
DocScrutinizer05de-facto: I'm absolutely sure RKI takes this into account for their R calculations05:19
jessif you join #freenode and type /who freenode/staff/*05:19
de-factoDocScrutinizer05, how would they take it into account? tests not done cant contribute05:19
de-factothey try to change guidelines to better targeting to raise the positivity quote05:20
DocScrutinizer05de-facto: maybe they know how many tests were not done, for example?05:20
de-factowell how would they know that? and how to know how many of those would have turned out positive?05:20
de-factoi mean Reff > 1 would require exponential increase in detected positive tested cases, yet if no tests can be offered to all those groups that were tested before, the tested incidence would drop automatically05:22
de-factoso its unclear if its a real decline in incidence or just in test cap05:22
DocScrutinizer05btw while labs are at limit, they still prioritize tests so the type of test done months ago already ist still always gettzing processed. What's falling off end of the board are the voluntary tests by travelers etc05:22
LjLtoday in Italy the percentage of positive tests went down compared to yesterday, but the percentage of positive *people* tested went *up*05:25
de-factoi wonder the same for the other EU countries that had a recent drop in detected cases05:25
de-factowell Germany did not had a drop yet unlike some others05:25
LjLso i guess despite it being a day-of-not-many-tests, unlike other times (every Monday really), this time they re-tested a lot of people that had been previously tested05:25
LjLi wouldn't say italy has had a drop, yesterday or the day before we had our maximum05:25
LjLi would say the growth might not be lower than exponential, without enough days to make that a certainty yet05:26
LjLmight now*05:26
LjLgod i hate that i mix up "now" and "not" so easily and they can almost always reverse the meaning of a sentence entirely05:26
de-factohttp://metrics.covid19-analysis.org/ namely Ireland, Netherlands, Belgium, Czech Rep, Slovakia, Slovenia, Iceland05:29
DocScrutinizer05or would you prefer that ~ ? ;-D05:29
LjLDocScrutinizer05, i have a ¬ that's better!05:29
LjLi had to fumble a bit with AltGr to find it again05:29
de-facto¡sǝᴉ⅂ ʇsnɾ sǝᴉ⅂05:53
LjLgood thing my computer is actually a tablet so i can turn it around05:54
tinwhiskerssurface?05:54
LjLew no, just some Asus thing05:55
tinwhiskersah. ok :-)05:55
LjLT302CA, probably the least known computer model ever05:55
ketaseveryone likes 1m2 sized tablets05:55
LjLit has a real keyboard, and a big battery in it too, just, it's an Asus keyboard, which means it SUCKS05:55
ketastransformer?05:56
tinwhiskersI *loooove* my surfacebook05:56
LjLketas, from that line, yes05:57
LjLmagnetically attached detachable keyboard+touchpad+battery+USB dock05:57
LjLhonestly i almost never detach it except for cleaning it05:57
tinwhiskerssounds interesting05:57
tinwhiskersMine is never attached to the keyboard05:57
ketasremember those devices where phone goes into screen?05:58
LjLusing it as a tablet is just not something i end up doing, probably not helped by GNOME looking like a touch interface but feeling a lot NOT like one05:58
ketasand it attaches to kbd05:58
LjL"convergence", yes05:58
BrainstormNew from BBC Health: (news): Coronavirus doctor's diary: 'We are first-hand witnesses of this devastation' → https://is.gd/mDTEUr05:58
tinwhiskersI use a BT mechanical keyboard and mouse and just have the screen as a floating screen on an arm05:58
LjLtinwhiskers, are you a circus juggler05:58
ketasah, padfone05:59
LjLmy oldschool computer tower is busy running Brainstorm05:59
tinwhiskersthe arm it's on swings around between my bed and my chair05:59
tinwhiskersde-facto: that's what I used to do back home but I needed something a bit more minimal for here.06:01
de-factoyeah understandable it just works too well for now, yet i did not got used to the luxury of having it portable because i never owned a laptop06:02
BrainstormNew from r/WorldNews: worldnews: Iran deprived of 5 million flu vaccine doses this year due to US sanctions – deputy health minister → https://is.gd/3RPDs006:08
de-factoactually id like to run gnome on a surface or such if i bought a portable device06:09
tinwhiskersat the time I got the surface linux did not support it at all well so I switched back windows after about 15 years of linux, but I expect that has changed by now.06:10
BrainstormNew from BBC Health: Covid: Seven-day-a-week clinics for vaccine proposed: Doctors' leaders say they "stand ready" to start providing a vaccine for up to 12 hours every day. → https://is.gd/l6iO1D06:35
BrainstormUpdates for Mayotte, France: +265 cases (now 4815), +1 deaths (now 46) since 4 days ago — Saskatchewan, Canada: +190 cases (now 4087), +1 deaths (now 29) since a day ago — Germany: +174 cases (now 689146) since 8 hours ago — US: +11016 cases (now 10.4 million), +57 deaths (now 244449) since 6 hours ago07:05
DocScrutinizer05RKI sleeps  :-/07:07
de-factoRKI: Germany infections +15332 (687200 total), fatalities +154 (11506 total)07:15
de-factounless they are still updating?07:15
de-factono warning anymore about updaing in process or such07:15
BrainstormUpdates for Andalusia, Spain: +12209 cases (now 173357), +104 deaths (now 2885) since 2 days ago — Pais Vasco, Spain: +5025 cases (now 78589), +7 deaths (now 2155) since 2 days ago — Murcia, Spain: +3124 cases (now 44511), +14 deaths (now 403) since 2 days ago — C. Valenciana, Spain: +3037 cases (now 73151), +21 deaths (now 1907) since 2 days ago07:20
de-factoDocScrutinizer05, do you know the first time of day where the csv fetch is safely complete from RKI?07:20
DocScrutinizer05usually 090007:21
DocScrutinizer05but the dashboard updates 000007:21
DocScrutinizer05except last night07:21
de-factonope actually the dashboard displays a popup warning that its old data from 0000 on until somewhere in the morning, e.g. 0700 or such?07:22
DocScrutinizer05?07:22
de-factobefore it displays the old data from previous day with warning, after it displays the new data without warning07:22
de-factobut sometimes it still seems to change in the morning, even without warning popup07:23
DocScrutinizer05https://i.imgur.com/wbp6WQZ.png07:24
DocScrutinizer05can't see any warning07:24
de-factoyeah now it does not show that warning anymore, so probably up to date07:24
DocScrutinizer05just the timestamplower left corner07:25
de-factoits a white popup in the middle of the page saying something like waring its old data still 07:25
de-factotry loading at 0010 or such07:25
de-factothen you will see the old day and the warning07:25
DocScrutinizer05aaah yes, *sometimes* that pops up some time in the night, between 0000 and maybe 0400 I seen that07:26
de-factoyeah it varies07:26
DocScrutinizer05today they don't show any new data, neither a warning07:26
de-factois that from yesterday still?07:27
DocScrutinizer05yes07:27
de-factomeh07:27
CoronaBot04/r/coronavirus: North Dakota hospitals at 100% capacity, Governor announces COVID-positive nurses can continue to work (10437 votes) | https://www.inforum.com/newsmd/coronavirus/6753876-With-North-Dakota-hospitals-at-100-capacity-Burgum-announces-COVID-positive-nurses-can-stay-at-work | https://redd.it/jrc8sg07:27
de-factoDocScrutinizer05, hmm i got an old tab in my smartphone open showing update dates of 2020-11-09 with +13363 and +6307:28
DocScrutinizer05wait! now it's from today and I didn't notice :-/07:29
DocScrutinizer05my mistake, sorry07:29
de-factoi think its updated07:29
de-factoyet sometimes the numbers increased a little bit even after no warning was shown07:30
de-factoso maybe sometimes they do some patching or such? nor sure07:30
BrainstormNew preprint: Optimal test-assisted quarantine strategies for COVID-19 by Bo Peng et al, published on 2020-11-09 at https://medrxiv.org/cgi/content/short/2020.11.06.20222398 [... want %more?]07:30
DocScrutinizer05anyway my "cronjob" (handmade) runs at 10:00 in the morning, since in rare cases 09:00 was too early07:30
DocScrutinizer05the csx on that data hoster is laaaaaate07:31
de-factoyeah i have my systemd timer also set at 10:00+random*30min07:31
de-factoand the download is a LOT faster when using gzip content encoding07:32
de-factoid reduces it by 30x or such07:32
DocScrutinizer05while ./update_server.sh; do echo "kill -s CONT $$"|at "10:00"; date; suspend; done   #;-D07:32
de-factocurl --silent --compressed --url "https://www.arcgis.com/sharing/rest/content/items/f10774f1c63e40168479a1feb6c7ca74/data" --output "covid-19-germany.csv" 07:34
DocScrutinizer05doesn't look like cron ;-)07:35
de-factoah i dont use cron07:35
de-factoi prefer systemd timers07:35
DocScrutinizer05me neither, I use at07:35
DocScrutinizer05systemd gives me the disease07:36
DocScrutinizer05OT here07:36
de-factook that --compressed reduces download time by 13x but still its quite an effect07:38
DocScrutinizer05btw 15332 today, 15352 (+20) last tuesday07:39
DocScrutinizer05toldya we're at R=1 :-D07:40
DocScrutinizer05did I?07:40
DocScrutinizer05well, actually we're already <1 as it maybe climbed a few days from last Tuesday, then dropped again07:43
de-factoI very much would hope so, yet i am convinced when daily new hospitalizations become a constant or declining series07:45
DocScrutinizer05wait another 2 weeks and you'll see that07:46
DocScrutinizer05well maybe just 1 week07:46
DocScrutinizer05I seem to recall some ISU doc said it was 10 days07:47
de-factoyes doubling 10 days07:47
DocScrutinizer05ICU*07:47
de-factoah delay yeah 10-14 days07:47
DocScrutinizer05they now are about to finsih a *simulation model* for predicting that number 10 to 14 days into the future - they worked on that for months, I really wonder what the heck is so complicated in it07:49
DocScrutinizer05RKI and some university07:50
DocScrutinizer05*NOW*!07:51
de-factooh btw the promised graph from Netherlands from the source: https://www.rivm.nl/documenten/wekelijkse-update-epidemiologische-situatie-covid-19-in-nederland https://www.rivm.nl/sites/default/files/2020-11/COVID-19_WebSite_rapport_wekelijks_20201103_1216.pdf (page 29)07:56
de-facto%title https://imgur.com/a/S5xoa5d https://i.imgur.com/qRqpLhC.png07:56
Brainstormde-facto: From imgur.com: COVID-19 Netherlands: TESTS, CASES, POSITIVITY - Album on Imgur07:56
de-factothe last week is incomplete data07:56
de-facto"De gegevens van week 44 zijn nog niet volledig"07:57
de-facto%tr <nl De gegevens van week 44 zijn nog niet volledig07:57
Brainstormde-facto, Dutch to English: The data for week 44 is not yet complete (MyMemory) — Week 44 data is not yet complete (Google)07:57
de-factohmm week 44 would be the last of October08:00
de-factothat pretty old data in that report table there08:00
de-factoso no wonder there is no decline visible08:00
de-factomeh08:00
de-factothe report is from 2020-11-03 so maybe we get a new one today?08:02
de-facto%tell de-facto check for update on https://www.rivm.nl/documenten/wekelijkse-update-epidemiologische-situatie-covid-19-in-nederland08:04
Brainstormde-facto, I'll pass de-facto your message when they are around. 08:04
BrainstormUpdates for Georgia: +2970 cases (now 63650), +22 deaths (now 521) since a day ago08:06
AtqueAnyone got 8,000,000,000 doses of a COVID-19 vaccine yet?08:17
BrainstormNew from The Indian Express: World: German frozen pork prompts new coronavirus case in China → https://is.gd/mf0j2q08:17
DocScrutinizer05duh, I thought Brainstorm was so cute to check for updates on a website and tell you if it finds any08:40
DocScrutinizer05took a while to realize it was a plain ~tell command08:41
BrainstormNew from CNBC Health: Coming months will be 'very rough,' U.S. doctor says despite good news on Covid-19 vaccine: It will take time before a coronavirus vaccine is available to the public and the months between now and then will be difficult, said epidemiologist Syra Madad. → https://is.gd/cUmxyc09:33
BrainstormNew from Medical Xpress: US allows 1st emergency use of a COVID-19 antibody drug: U.S. health officials have allowed emergency use of the first antibody drug to help the immune system fight COVID-19, an experimental approach against the virus that has killed more than 238,000 Americans. → https://is.gd/kZNeaM10:01
BrainstormNew from Medical Xpress: As virus spikes, Europe runs low on ICU beds, hospital staff: In Italy lines of ambulances park outside hospitals awaiting beds, and in France the government coronavirus tracking app prominently displays the intensive care capacity taken up by COVID-19 patients: 92.5% and rising. In the ICU in Barcelona, there is no end in [... want %more?] → https://is.gd/QajdIc10:11
BrainstormNew from StatNews: How might a mask mandate play out? Look to the battle over seat belt laws: Like masks during the Covid-19 pandemic, the fight for seat belt laws was met with misinformation and pushback around personal freedom. → https://is.gd/SyAJTV10:42
BrainstormNew from StatNews: First Opinion: Opinion: The pandemic is accelerating transformation agendas in the clinical research industry → https://is.gd/fW3eWC10:52
BrainstormUpdates for Germany: +635 cases (now 689607), +3 deaths (now 11660) since 12 hours ago11:36
BrainstormNew from The Indian Express: World: UK PM cautiously welcomes ‘loud toot’ of vaccine bugle → https://is.gd/AEczBo12:04
BrainstormUpdates for Switzerland: +5980 cases (now 235202), +28 deaths (now 2930) since 11 hours ago12:05
BrainstormUpdates for Switzerland: +35 deaths (now 2937) since 12 hours ago12:36
BrainstormNew from PubMed: Can BCG vaccine protect against COVID-19 via trained immunity and tolerogenesis?: As the number of infections and mortalities from the SARS-CoV-2 pandemic continues to rise, the development of an effective therapy against COVID-19 becomes ever more urgent. A few reports showing a positive correlation between BCG vaccination and reduced [... want %more?] → https://is.gd/LWdkcD12:50
BrainstormUpdates for Germany: +2171 cases (now 691143), +22 deaths (now 11679) since 13 hours ago12:51
BrainstormUpdates for Belarus: +1038 cases (now 108300), +5 deaths (now 1016) since a day ago — Switzerland: +41 deaths (now 2943) since 12 hours ago13:05
BrainstormNew from "Cluster 5" on Wikipedia: 91.82.128.254: /* Name */Explain the mutation codes.: Name: Explain the mutation codes. ← Previous revision Revision as of 12:02, 10 November 2020 Line 7: Line 7: == Name == == Name == − In Denmark there have been five clusters of mink variants of SARS-CoV-2; the Danish [[Statens Serum Institut|State Serum [... want %more?] → https://is.gd/74bzDF13:09
BrainstormNew from BMJ: Covid-19: GPs to get {pound}12.58 per dose to deliver vaccine from December: The NHS has published an agreement to enable general practices to start delivering a covid-19 vaccine from as early as next month.A new directed enhanced service (DES), published 10 November,12 says... → https://is.gd/HKpoPq13:47
BrainstormUpdates for Switzerland: +57 deaths (now 2959) since 13 hours ago13:51
BrainstormNew from "Cluster 5" on Wikipedia: 86.52.69.254: /* Timeline */: Timeline ← Previous revision Revision as of 12:53, 10 November 2020 Line 16: Line 16: {{cite web|author=Grove Krause, Tyra|title=Mutationer i minkvirus|url=https://www.ssi.dk/aktuelt/nyheder/2020/mutationer-i-minkvirus|accessdate=6 November 2020|publisher=Statens Serum [... want %more?] → https://is.gd/74bzDF13:56
BrainstormUpdates for US: +14362 cases (now 10.4 million), +78 deaths (now 244470) since 13 hours ago14:06
CoronaBot04/r/covid19: Lilly's neutralizing antibody bamlanivimab (LY-CoV555) receives FDA emergency use authorization for the treatment of recently diagnosed COVID-19 (80 votes) | https://investor.lilly.com/news-releases/news-release-details/lillys-neutralizing-antibody-bamlanivimab-ly-cov555-receives-fda | https://redd.it/jrbdde14:12
BrainstormNew from The Indian Express: World: China says it is providing convenience to stranded Indian ship under COVID-19 limits → https://is.gd/7F2g8H14:15
BrainstormUpdates for Sweden: +15779 cases (now 162240), +35 deaths (now 6057) since 4 days ago14:20
BrainstormNew from Medical Xpress: 90% efficacy for Pfizer's COVID-19 mRNA vaccine is striking, but we need to wait for the full data: German biotech company BioNTech and US pharmaceutical Pfizer announced on Monday promising early results from their phase 3 clinical trial for a vaccine against SARS-CoV-2, the virus that causes COVID-19. → https://is.gd/HoQH4w14:34
BrainstormUpdates for Germany: +4498 cases (now 693470), +43 deaths (now 11700) since 15 hours ago14:35
BrainstormNew from The Indian Express (Health): Destination of the week: World gets its first cruise ship with COVID-19 testing lab → https://is.gd/gqyN1z14:43
BrainstormUpdates for Switzerland: +66 deaths (now 2968) since 14 hours ago14:50
BrainstormNew from r/Coronavirus: Coronavirus: Daily Discussion Post - November 10 | Questions, images, videos, comments, unconfirmed reports, theories, suggestions → https://is.gd/xAeNIL15:02
BrainstormUpdates for US: +16072 cases (now 10.4 million), +114 deaths (now 244506) since 14 hours ago — Germany: +5485 cases (now 694457), +59 deaths (now 11716) since 16 hours ago15:21
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: FDA OKs Lilly drug for Covid-19; most Americans would get a Covid-19 shot if infection risk drops by half → https://is.gd/ISZNSo15:29
BrainstormUpdates for US: +17507 cases (now 10.4 million), +127 deaths (now 244519) since 15 hours ago15:35
BrainstormNew from Medical Xpress: COVID-19 vaccine: Reliable communications needed to beat 'infodemic' of misinformation: A coordinated program to combat anti-vaxx misinformation and encourage confidence in a COVID-19 vaccine is essential if a take-up target of eight in ten people in the UK is to be achieved, according Oxford Professor Melinda Mills, author of [... want %more?] → https://is.gd/m8Vidd15:49
BrainstormUpdates for Germany: +6444 cases (now 695416), +70 deaths (now 11727) since 16 hours ago15:50
BrainstormUpdates for US: +17593 cases (now 10.4 million), +129 deaths (now 244521) since 15 hours ago16:05
BrainstormNew from CNBC Health: (news): Not wanting to be outdone by Pfizer, Putin says Russia is about to register a third Covid vaccine → https://is.gd/iJyL3Q16:07
BrainstormNew from Medical Xpress: Scabies: The neglected tropical disease no one wants to talk about: Some diseases are more likely to enter public conversation than others. COVID-19 has dominated the public discourse in 2020, while cancer and AIDS are high-profile diseases that attract significant scientific and media attention. You can safely discuss these [... want %more?] → https://is.gd/driJMA16:17
BrainstormUpdates for US: +18931 cases (now 10.4 million), +141 deaths (now 244533) since 15 hours ago — Germany: +7014 cases (now 695986), +79 deaths (now 11736) since 17 hours ago16:21
CoronaBot04/r/covid19: Detailed 3D model of SARS-CoV-2 made by KAUST (81 votes) | https://discovery.kaust.edu.sa/en/article/991/peering-under-the-%22hood%22-of-sars-cov-2 | https://redd.it/jrkn0z16:30
BrainstormUpdates for US: +22346 cases (now 10.4 million), +197 deaths (now 244589) since 16 hours ago — Netherlands: +3980 cases (now 419412), +98 deaths (now 8141) since a day ago16:36
BrainstormUpdates for Germany: +8567 cases (now 697539), +91 deaths (now 11748) since 17 hours ago — Canada: +2607 cases (now 270123) since 17 hours ago — US: +22355 cases (now 10.4 million) since 16 hours ago16:50
LeoBodnarenzo16:56
LeoBodnaroh hello wrong window16:57
jacklswlol enzo who?16:57
jacklswferrari?16:57
BrainstormNew from StatNews: Restaurants and gyms were spring ‘superspreader’ sites. Occupancy limits could control spread, new study predicts: Sharply limiting the occupancy of restaurants, gyms, cafes, hotels, and houses of worship could control the raging pandemic without resorting to lockdowns, a new study suggests. → https://is.gd/BFi1Hc17:04
BrainstormUpdates for US: +23288 cases (now 10.4 million), +234 deaths (now 244626) since 16 hours ago17:05
BrainstormNew from The Indian Express (Health): Destination of the week: Family ‘mistakenly’ made to fly back home despite presenting negative COVID-19 test report in Hawaii → https://is.gd/AYJatM17:13
BrainstormNew from "Cluster 5" on Wikipedia: 194.255.34.169: /* Timeline */  full name of SSI added: Timeline: full name of SSI added ← Previous revision Revision as of 16:22, 10 November 2020 Line 13: Line 13: == Timeline == == Timeline == − On 4 November 2020, Prime Minister of Denmark [[Mette Frederiksen]] stated that a mutated coronavirus was being [... want %more?] → https://is.gd/74bzDF17:32
BrainstormUpdates for Vermont, US: +47 cases (now 2462) since a day ago — US: +23335 cases (now 10.4 million) since 17 hours ago17:36
BrainstormNew from BBC Health: Covid: China's Sinovac vaccine trial halted in Brazil: The head of the institute conducting the trials says there was a death but not caused by the vaccine. → https://is.gd/bePXs917:50
BrainstormUpdates for US: +26769 cases (now 10.4 million), +262 deaths (now 244654) since 17 hours ago17:51
LjL%title https://www.thelancet.com/pdfs/journals/lanpsy/PIIS2215-0366(20)30462-4.pdf since the article from Reuters doesn't link to the study, as usual18:00
BrainstormLjL, the URL could not be loaded 18:00
LjLand the lancet doesn't like my bot i guess18:00
LjL"Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62354 COVID-19 cases in the USA"18:01
BrainstormUpdates for Algeria: +753 cases (now 63446), +15 deaths (now 2077) since a day ago — Italy: +35090 cases (now 995463), +580 deaths (now 42330) since a day ago — US: +27980 cases (now 10.4 million), +329 deaths (now 244721) since 17 hours ago — Canada: +3770 cases (now 271286), +50 deaths (now 10617) since 18 hours ago18:05
LjLugh18:05
LjLde-facto, Italy's deaths ↑18:06
BrainstormNew from BMJ: Telemedicine: don’t discount the value of in-person GP clinics to the medical trainee: The move towards telemedical consultation in light of the covid-19 pandemic is driving innovation in general practice at pace. Omitted from consideration in Stokel-Walker’s otherwise excellent... → https://is.gd/XetKKJ18:09
rpifantrue18:10
rpifanbut only if the dr is not a german18:10
DocScrutinizer05just a heads up: the mink issue is most likely a non-issue, i.e. irrelevant for human covid18:27
bin_bashDocScrutinizer05: source?18:28
DocScrutinizer05Drosten podcast referring a paper of today from danish(?) scientists18:30
bin_bashplease link the paper18:30
BrainstormUpdates for US: +37702 cases (now 10.4 million), +419 deaths (now 244811) since 18 hours ago18:36
DocScrutinizer05I'm listening to the podcast right now. As soon as the transscript gets available and provides a link, I will share it18:40
DocScrutinizer05bottom line: of the 4 mutations in cluster5 only one is relevant and this one is a convergent (>= 4 times already) recurring adaption to mink host and causes the virus to replicate *less* in humans. The allegedly inferior susceptibility to antibodies is arguable aka marginal / few weak data 18:43
BrainstormUpdates for Germany: +10030 cases (now 699002), +99 deaths (now 11756) since 19 hours ago18:50
rpifanr we having a harder lockdwon or not18:50
DocScrutinizer05bottom line of bottom line: vaccination and antibody *cocktails* are most likely NOT affected at all by cluster518:54
DocScrutinizer05and cluster5 is in no way more dangerous per se18:54
DocScrutinizer05disclaimer: as I understand it!!!18:55
chicoSeems like cluster 5 mutates faster?18:57
BrainstormNew from CNBC Health: Cruise bookings rise on coronavirus vaccine news, Norwegian Cruise Line CEO says: "Bookings, the last 24 hours, yesterday, were pretty good ... and that, I think, is attributable to the vaccine news," said Norwegian CEO Frank Del Rio. → https://is.gd/4hzUBf18:57
DocScrutinizer05>>Seems like cluster 5 mutates faster<< nothing suggesting that. The mutation is driven by virus "living" in minks and adapting to that environment. It happened 4 times already, independently, which is known as convergence19:01
DocScrutinizer05the mutation is an advantage for this strain **in minks**, in humans it's a DISadvantage19:02
LjLuh, i remember hearing that one of the two antibodies in Regeneron *would* likely be affected by Cluster 519:05
LjLif it sticks to the S-protein but the S-protein has changed, that would make sense19:06
bin_bashi'll wait to see the paper tbh19:09
DocScrutinizer05LjL: that's why antibody medications are always a cocktail of different types of antibodies. 3 seems to be considered a good minimum, also seen elsewhere e.g. by TBC treatment19:14
DocScrutinizer05I'm sure that paper will come up huge in press in the next days19:15
LjL%paper mink denmark19:15
BrainstormLjL: An error occurred while searching.19:15
LjL%paper mink19:16
BrainstormLjL, 7 papers: Jumping back and forth: anthropozoonotic and zoonotic transmission of SARS-CoV-2 on mink farms by Bas B. Oude Munnink et al, published on 2020-09-01 at https://biorxiv.org/cgi/content/short/2020.09.01.277152 [... want %more?]19:16
LjL%more19:16
BrainstormNew from CNBC Health: (news): U.S. officials warn of early challenges administering Eli Lilly's coronavirus antibody drug → https://is.gd/grCfmr19:16
BrainstormLjL, [...] transmitted to humans via minks, tied primarily to [[Mink farm|mink farms]] in [[Northern Jutland]]. A report by the SSI found that there had been at least 12 human infections involving this mutation in Northern Jutland (being referred to as "cluster 5"), and its [[Antibody|antibody response]] was weak. While the institute suggested that this mutation was [...] → https://paste.ee/p/fA0rv19:16
BrainstormLjL, [...] SARS-CoV2 infection in farmed mink, Netherlands, April 2020 by Nadia Oreshkova et al, published on 2020-05-18 at http://biorxiv.org/cgi/content/short/2020.05.18.101493 [...] → https://paste.ee/p/Sf2Xi19:16
DocScrutinizer05maybe for now it's more useful to losten/read the today's Drosten talk19:16
LjLoh19:16
LjLthey *dropped* their plan for mass culling of mink19:17
LjLnow i had missed that news19:17
LjLlooks like Parliament stopped that19:17
LjLso it's not because the paper is reassuring, just because parliament didn't agree with government :\19:17
LjLhttps://www.theguardian.com/environment/2020/nov/09/denmark-drops-plans-for-mass-mink-cull-after-covid-mutation-fears19:18
LjLi found https://www.ssi.dk/-/media/arkiv/dk/aktuelt/nyheder/2020/2020-working-paper-on-sarscov2-spike-mutations-arising-in-danish-mink-their-1-spread-to-humans-and-n.pdf?la=en which Google suggest may be the new paper, aiui, but it isn't loading19:19
DocScrutinizer05coronavirus-update "keine angst vor mutationen (64)" https://www.ndr.de/nachrichten/info/podcast4684.html19:19
BrainstormUpdates for Spain: +17395 cases (now 1.4 million), +411 deaths (now 39756) since a day ago — US: +41882 cases (now 10.5 million), +449 deaths (now 244841) since 18 hours ago19:21
LjLare we sure this is an appropriate hyperlink to "gene cluster" here https://en.wikipedia.org/w/index.php?title=Cluster_5&type=revision&diff=988040929&oldid=988021902 ? it's about genes, sure, but i understood "cluster" here as clusters in an outbreak...19:22
LjLhttps://webcache.googleusercontent.com/search?q=cache:L89QeN6PD-cJ:https://www.ssi.dk/-/media/arkiv/dk/aktuelt/nyheder/2020/2020-working-paper-on-sarscov2-spike-mutations-arising-in-danish-mink-their-1-spread-to-humans-and-n.pdf%3Fla%3Dda+&cd=12&hl=en&ct=clnk&gl=it&client=firefox-b-d19:23
DocScrutinizer05according to Drosten of today, "cluster" refers to a group of similar mutations in sequencing, in this context19:25
LjL"The clinical isolates bearing the Y453F spike mutation replicated as efficiently as the unmutated/wildtype SARS-CoV-2 virus that predominates in Denmark (data not shown). Conversely, the SARS-CoV-2 virus with four mutations grew slower than both the wildtype virus and other SARS-CoV-2 virus isolates (Fig. 2)."19:25
BrainstormNew from "Cluster 5" on Wikipedia: Biscuit-in-Chief: /* Name */link, {{cn}}: Name: link, {{cn}} ← Previous revision Revision as of 18:18, 10 November 2020 Line 7: Line 7: == Name == == Name == − In Denmark there have been five clusters of mink variants of SARS-CoV-2; the Danish [[Statens Serum Institut|State Serum Institute]] (SSI) has designated [... want %more?] → https://is.gd/74bzDF19:25
LjL"The different convalescent plasma were not equally affected by the ΔFVI-spike mutant virus. The two plasma samples with high neutralization titers were largely unaffected, while plasma with low and intermediate titers were more likely to experience a loss in neutralization activity (Fig. 3a)."19:26
LjLnot much that we didn't already know, except that maybe in the language i don't really understand in the rest of the paper (which isn't very long) there is key information i don't understand19:27
bin_bashDocScrutinizer05: i don't think listening to a podcast is a good way to get that kind of information without a written souce and references19:28
bin_bashdifficult to peer review a podcast19:28
LjLbin_bash, that's probably why he at first said he'd link it after they publish the transcript19:29
bin_bashyeah i know19:32
bin_bashbut then he said the podcast is more useul19:33
bin_bashuseful19:33
bin_bashand i was just disagreewing with that19:33
DocScrutinizer05bin_bash: if you're a scientist competent to di peer review, you won't do a peer review of Drosten's podcasts, you'll already have seen that paper and can tell me if Drosten was right in _his_ "peer review" he shared to us19:35
LjLthe paper, at least the working version that i linked to, really don't say much of anything different than we already know...19:36
bin_bashDocScrutinizer05: i'm not the one doing the peer review, i want to see what others have reviewed. podcasts are large inaccessible19:36
LjLanyway it seems irresponsible to veto the culling of these mink when it's clear that mink are very susceptible and the virus can mutate in them very easily19:36
bin_bashhence why transcripts are so critical19:36
BrainstormUpdates for United Kingdom: +18720 cases (now 1.2 million), +532 deaths (now 49770) since 12 hours ago19:36
bin_bashLjL: yeah i agree19:36
LjLbin_bash, peer review takes months to happen19:36
bin_bashi know19:37
bin_bashbut if it's at least published19:37
bin_bashthere will be comments19:37
DocScrutinizer05that's why I rather listen to Drosten, he's more competent than I am and can explain what that paper means, if it is trustworthy or where it lacks evidence, and so on19:37
bin_bashlike there have been comments on other papers about fomite transmission being exaggerated19:37
LjLbin_bash, well the person DocScrutinizer05 is referring to is https://en.wikipedia.org/wiki/Christian_Drosten which you'll see is not just a random podcaster. if you're looking for competent "comments", his would qualify19:38
bin_bashDocScrutinizer05: ya for sure let me know when you have the transcript i'd like to read it19:38
bin_bashLjL: my problem is with the format.19:38
LjLmy problem is with the german :P19:38
bin_bashhence why i look forward to the transcript19:38
bin_bashoh right, if it's in german that's another issue haha19:38
generawhat are you talking about? the last/current NDR podcast?19:39
genera"das update"19:39
LjLalmost certainly yes19:40
LjL(64) Keine Angst vor Mutationen19:40
LjLSendung: Das Coronavirus-Update von NDR Info | 10.11.2020 | 16:45 Uhr | von Korinna Hennig19:40
LjLErste Impfstoffdaten hält Christian Drosten für ermutigend. Und: Das Virus verändert seine Eigenschaften bisher kaum.19:40
generagreat. its like in the middle ages, german is again the language of relevant research19:42
genera:-)19:42
DocScrutinizer05watch https://www.ndr.de/nachrichten/info/Coronavirus-Update-Die-Podcast-Folgen-als-Skript,podcastcoronavirus102.html for transscript appearing for 6419:42
LjLgenera, okay to be fair Drosten is certainly competent but his podcast isn't "research" :P19:43
DocScrutinizer05genera: no, not really19:43
DocScrutinizer05LjL: +119:43
BrainstormNew from Medical Xpress: RNA structures of coronavirus reveal potential drug targets: The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University. The RNA structures are potential targets for the [... want %more?] → https://is.gd/dkm7Ch19:45
DocScrutinizer05just for filling in factoids: Drosten is one of the top SARS virologists globally19:47
DocScrutinizer05maybe THE top virologist for SARS19:47
DocScrutinizer05and he very obviously has no bias or hidden agenda of any kind19:49
BrainstormUpdates for Montana, US: +1098 cases (now 41151), +5 deaths (now 462) since a day ago — US: +45325 cases (now 10.5 million), +464 deaths (now 244856) since 19 hours ago19:50
SkunnyWife got a negative result19:53
BrainstormNew from Medical Xpress: How to host a safe holiday meal during coronavirus – an epidemiologist explains her personal plans: Like many people in this unusual year, I am adjusting my family's holiday plans so that we can all be safe during the ongoing coronavirus pandemic. → https://is.gd/rvNI1P19:55
BrainstormNew from Medical Xpress: Vaccine innovation sparks hope, questions: Reports that one of the vaccines for COVID-19 has shown highly promising results are a ray of hope for a world in the shadow of surging virus cases. → https://is.gd/1dvAuT20:05
BrainstormUpdates for Illinois, US: +12623 cases (now 511183), +82 deaths (now 10645) since 23 hours ago — US: +62301 cases (now 10.5 million), +615 deaths (now 245007) since 19 hours ago — Canada: +4153 cases (now 271669), +55 deaths (now 10622) since 20 hours ago — Germany: +10285 cases (now 699257), +107 deaths (now 11764) since 21 hours ago20:06
BrainstormNew from Medical Xpress: Doctors may be better equipped to handle latest virus surge: The latest surge in U.S. coronavirus cases appears to be much larger than the two previous ones, and it is all but certain to get worse—a lot worse. But experts say there are also reasons to think the nation is better able to deal with the virus this time. → https://is.gd/OxeOIr20:15
BrainstormUpdates for Ohio, US: +6508 cases (now 261482), +23 deaths (now 5588) since a day ago — US: +71858 cases (now 10.5 million), +666 deaths (now 245058) since 19 hours ago20:21
LjLSkunny, are you isolating from each other in some way?20:25
Skunnyim on day 11 now20:28
Skunnyyeah I had my own room20:28
SkunnyI would watch some tv. we have a big living room and I wore my we all wore N95 mask20:29
LjLyou might not be all that infectious now on day 11. but you also might20:29
SkunnyI would say it worked out cause she tested Sunday20:29
Skunnyright20:29
Skunnystill not licking the wife yet lol20:29
LjLSkunny, well, it worked out, or you were lucky. i think only around 40% of people who live with infected people become infected in turn20:29
Skunnyand i have hand sanitizer all over the house20:29
Skunnyyeah for sure20:29
LjLand by "only" i mean... of course it's a very large amount, but giving the infectiousness of this virus, i'd have expected >90%20:30
Skunnyor she had it already back in feb when she was sick I dunno20:30
LjLone of the many mysteries about it20:30
LjLSkunny, in februrary? which country?20:30
Skunnyus20:30
Skunnyshe was pretty sick20:30
LjLmaybe you can get an antibody test somewhere20:30
Skunnyyeah, looking into that today20:30
LjLbut if you do, make sure it's a reasonably decent one, there's a lot of crap around20:30
Skunnyso many BS testing20:31
Skunnyrapid test are crap too20:31
Skunnywaiting on sons test right now20:31
BrainstormUpdates for Germany: +12598 cases (now 701570), +141 deaths (now 11798) since 21 hours ago — US: +72062 cases (now 10.5 million), +669 deaths (now 245061) since 20 hours ago20:35
BrainstormUpdates for US: +77227 cases (now 10.5 million), +729 deaths (now 245121) since 20 hours ago20:50
Jigsy%cases World21:02
BrainstormJigsy: In World, there have been 51.8 million confirmed cases (0.7% of the population) and 1.3 million deaths (2.5% of cases) as of 12 minutes ago. 880.6 million tests were performed (5.9% positive). Fatality can be broadly expected to lie between 0.3% (assuming prevalence as in tests) and less than 3.4% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=World for time series data.21:02
TASAa21:05
TASAinverse placebo ?21:05
BrainstormUpdates for US: +85365 cases (now 10.5 million), +826 deaths (now 245218) since 20 hours ago21:06
BrainstormNew from WebMD: Can You Safely Host Holiday Events During COVID-19?: After months of separation from friends and family due to COVID-19, many people hope to reconnect over such holidays as Christmas and Hanukkah. But health experts continue to encourage people to practice safe behaviors and avoid situations that could expose them or their loved ones to [... want %more?] → https://is.gd/PK5qF621:08
BrainstormUpdates for US: +97629 cases (now 10.5 million), +982 deaths (now 245374) since 20 hours ago21:21
BrainstormUpdates for US: +104849 cases (now 10.5 million), +1063 deaths (now 245455) since 21 hours ago — Germany: +16369 cases (now 705341), +196 deaths (now 11853) since 22 hours ago21:35
DocScrutinizer05>>only around 40% of people<< iirc today I heard in that podcast: 25% with flu, only 15% with sars-cov2. I might recall wrong21:37
DocScrutinizer05for sure it's not a universal constant :-) largely depends on particular situation and habits21:38
BrainstormUpdates for US: +109588 cases (now 10.5 million), +1079 deaths (now 245471) since 21 hours ago21:51
BrainstormNew from PLOS ONE: The immunoglobulin G antibody response to malaria merozoite antigens in asymptomatic children co-infected with malaria and intestinal parasites: by Crespo’o Mbe-cho Ndiabamoh, Gabriel Loni Ekali, Livo Esemu, Yukie Michelle Lloyd, Jean Claude Djontu, Wilfred Mbacham, Jude Bigoga, Diane Wallace Taylor, Rose Gana Fomban Leke [... want %more?] → https://is.gd/UQcun222:01
BrainstormUpdates for US: +110154 cases (now 10.5 million) since 21 hours ago22:05
CoronaBot04/r/covid19: Working paper on SARS-CoV-2 spike mutations arising in Danish mink, their spread to humans and neutralization data. (81 votes) | https://files.ssi.dk/Mink-cluster-5-short-report_AFO2 | https://redd.it/jrl0f122:08
BrainstormUpdates for US: +116398 cases (now 10.5 million), +1105 deaths (now 245497) since 21 hours ago22:20
BrainstormUpdates for US: +118745 cases (now 10.5 million), +1122 deaths (now 245514) since 22 hours ago22:36
DocScrutinizer05*wieso` bringen die ARD tagesthemen ein 2 sekunden bild von "meiner" U-Bahn station??? voellig bezugslos in nem beitrag ueber den impfstoff22:49
de-factooh nice description of cluster 5 mutations https://files.ssi.dk/Mink-cluster-5-short-report_AFO222:49
Brainstormde-facto: At 2020-11-10 07:04:34 UTC, de-facto told you: check for update on https://www.rivm.nl/documenten/wekelijkse-update-epidemiologische-situatie-covid-19-in-nederland22:49
DocScrutinizer05oh sorry, wrong channel22:49
de-factoright, thanks Brainstorm 22:49
de-factooh no it converted to 40422:50
LjL:\22:50
BrainstormUpdates for US: +119637 cases (now 10.5 million), +1125 deaths (now 245517) since 22 hours ago — Canada: +4891 cases (now 272407) since 23 hours ago22:50
LjLde-facto, well the paper you linked was previously elsewhere except i didn't have time to get it from there but i found it in google's cache22:50
LjLde-facto, and by doing the same thing with this .nl one i reach https://www.rivm.nl/sites/default/files/2020-11/COVID-19_WebSite_rapport_wekelijks_20201103_1216.pdf22:51
de-factoah here the archive got it https://www.rivm.nl/coronavirus-covid-19/actueel/wekelijkse-update-epidemiologische-situatie-covid-19-in-nederland22:51
LjLwhich is however long as hell22:51
de-factoyeah there is an update as i guessed today https://www.rivm.nl/sites/default/files/2020-11/COVID-19_WebSite_rapport_wekelijks_20201110_1158.pdf22:52
de-factopage 29 positivity went down?22:54
LjL%tr <nl aantal22:54
BrainstormLjL, Dutch to English: number (MateCat, Google) — count (MateCat) — Quantity (MateCat)22:55
de-factoits funny Dutch sounds very similar to German so aantal sounds like Anzahl, meaning "Number of"22:56
rpifandutch spelling is very close to german22:59
rpifani can read a lot of dutch with my german22:59
rpifanbut speaking is something else22:59
de-factoyup23:01
LjLdon't tell dutchmen, but linguistically dutch is really on a dialect continuum with the neighboring dialects of german (which however don't have a high formal status, unlike dutch)23:02
rpifanyea it is23:04
BrainstormNew from Medical Xpress: Should college students go home for the holidays?: Thanksgiving is traditionally an intimate gathering of family and friends. And, for college students, the fall break in semester is an opportunity to travel home to see the family for a few days. With COVID-19 cases increasing at a high rate in some parts of the U.S., that trek [... want %more?] → https://is.gd/0Pyjj423:04
de-facto%title https://imgur.com/a/55iiMF2 https://i.imgur.com/KI7yuIX.png source: newest https://www.rivm.nl/sites/default/files/2020-11/COVID-19_WebSite_rapport_wekelijks_20201110_1158.pdf (page 29)23:05
Brainstormde-facto: From imgur.com: COVID-19 Netherlands: Tests, Cases, Positivity - Album on Imgur23:05
rpifanim actually doing the german right now23:05
rpifantalkign in the german to telekom23:05
rpifanits a bit strange thats after only 24 months or 23:05
rpifanso im able to communicate at least basically with telekom23:05
BrainstormUpdates for US: +119735 cases (now 10.5 million), +1127 deaths (now 245519) since 22 hours ago23:06
de-factoso it really looks like Netherlands surpassed a peak in testing positivity in the week ending at 2020-10-2523:06
de-factodid they change their testing strategy by then or is that incidence itself?23:07
LjLwell the number of tests had steadily being going up23:08
LjLthen suddenly it goes down23:08
LjLand coincidentally the percentage of positives changes too23:08
de-factoi mean their incidence dropped (as did their testing) but also their positivity e.g. cases / tests23:08
LjLto me that indicates a change in testing strategy, whether on purpose or by necessity23:08
LjLde-facto, yes, but the same happened yesterday in italy. does it mean we have fewer cases today? not so much23:08
LjLi know that usually fewer tests = higher % positive23:09
LjLbut perhaps even more importantly, fewer tests = something is different23:09
de-factowell only if targeting changed, e.g. if they only test high risk groups or symptomatic or such23:09
de-factoi hate they are not screening random people to get an representative picture23:10
de-factoits such a guessing game, maybe they did this and got that effect 23:10
de-factobut testing positivity going down is a good sign in my opinion, why would they change their testing targeting to include less probable cases while reducing amount of tests?23:13
de-factomeaning if the drop in positivity is not due to that it may be real23:14
BrainstormNew from Medical Xpress: What are we drinking during the pandemic?: It might not be surprising to learn but people are drinking more than usual during the pandemic. → https://is.gd/ZO6PsA23:15
de-factoyeah... Green Tea :)23:15
TASAwhat if23:16
TASAi told you23:16
TASA..23:16
TASA.23:16
LjLyeeeeeeees?23:17
TASAwhat are they measuring the mutations with23:17
TASA?23:18
LjLi assume it's "sequencing"23:18
TASAbut how ?23:18
TASAhow do they glean the information in order ?23:18
TASAwith what tool ?23:18
LjLi'm dying to know23:19
BrainstormUpdates for Wyoming, US: +1232 cases (now 19242), +13 deaths (now 127) since a day ago — US: +123213 cases (now 10.5 million), +1161 deaths (now 245553) since 22 hours ago — Canada: +5107 cases (now 272623) since 23 hours ago23:20
TASAi B back soon23:20
TASAgoing to get a drink23:20
TASAbe about 1523:20
TASAplease tell me someone how they identify that it is covid23:21
TASAback in 1823:22
LjLTASA, you're making a lot of noise while not actually even clarifying whether you're asking a question or teasing and answer or both23:22
LjLcolor me unamused23:22
BrainstormNew from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 10 novembre 2020: Ulteriori misure  urgenti  in  materia  di  contenimento  e  gestionedell'emergenza epidemiologica da COVID-19. (20A06211) → https://is.gd/4Yyjuw23:24
LjLthey are probably declaring some more regions "red" or "orange" zones (finally)23:29
LjLgah, Campania is still nothing23:30
LjLidiots23:30
rpifanidiota!23:32
rpifanyou mean23:32
BrainstormUpdates for US: +123517 cases (now 10.5 million), +1165 deaths (now 245557) since 23 hours ago23:36
LjLrpifan, well no i would mean idioti23:42
BrainstormNew from StatNews: Pharma: STAT+: FDA requires Lilly to hire consultants to monitor quality control problems at plant making Covid-19 drug → https://is.gd/kMKKHg23:43
rpifanidk how plurals work in italian23:43
rpifanin spanish its idiotas23:43
LjLthey work more complicatedly than spanish, but probably easier than german23:50
rpifanyupp23:50
BrainstormUpdates for Bulgaria: +4390 cases (now 83366), +80 deaths (now 1851) since a day ago — US: +124203 cases (now 10.5 million), +1168 deaths (now 245560) since 23 hours ago — Germany: +16668 cases (now 705640), +203 deaths (now 11860) since a day ago — Switzerland: +111 deaths (now 3013) since 23 hours ago23:51
BrainstormNew from Ars Technica: Science: Dutch scientists reconstruct spread of coronavirus through mink farms → https://is.gd/4vqjK323:53

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