libera/##covid-19/ Tuesday, 2020-12-01

BrainstormNew from https://covid19.specops.network : ljl-covid: Add press release with primary efficacy analysis of Moderna vaccine → https://is.gd/hFxtAN00:01
BrainstormUpdates for Germany: +14072 cases (now 1.1 million), +329 deaths (now 16862) since 17 hours ago00:05
LjLde-facto, ah i forgot to ask you, when you mentioned metager, do you know about searx?00:24
BrainstormNew from https://covid19.specops.network : Update ToC with new sections: although I should probably rework the section, without separate "Science" and "Medicine", some of the stuff in Science should be in Epidemiology and I dunno what else → https://is.gd/Nx1FaP01:02
BrainstormUpdates for Canada: +7922 cases (now 378139), +106 deaths (now 12130) since a day ago01:05
BrainstormNew from https://covid19.specops.network : ljl-covid: Add CNN leak, not sure about the merits but it fits into News for sure → https://is.gd/7Us1Js01:15
BrainstormUpdates for France: +4530 cases (now 2.2 million) since 22 hours ago — Netherlands: +3742 cases (now 525414), +19 deaths (now 9401) since 22 hours ago01:22
BrainstormNew from r/WorldNews: worldnews: Leaked documents reveal China's mishandling of the early stages of Covid-19 pandemic → https://is.gd/CDPzun01:40
BrainstormUpdates for Channel Islands: +81 cases (now 1299) since 3 days ago02:05
BrainstormNew from Gazzetta Ufficiale italiana: DECRETO-LEGGE 30 novembre 2020, n.157: Ulteriori misure urgenti  connesse  all'emergenza  epidemiologica  daCOVID-19. (20G00183) → https://is.gd/qQOpv902:17
BrainstormUpdates for New Zealand: +3 cases (now 2059) since 23 hours ago02:51
BrainstormNew from r/WorldNews: worldnews: Leaked documents reveal China's mishandling of the early stages of Covid-19 → https://is.gd/gPJOeu03:06
BrainstormNew from The Indian Express: World: China gave COVID-19 vaccine candidate to North Korea’s Kim, US analyst says → https://is.gd/rVQ5hm03:30
BrainstormNew from r/WorldNews: worldnews: Leaked documents show China lied about Covid-19 case totals and mishandled pandemic. In some instances, the number of deaths reported internally were more than double the figures released to the public. → https://is.gd/3H3Beq04:19
BrainstormNew from CNBC Health: Biden Covid advisor on Dr. Atlas resignation: 'I am relieved' because he wasn’t qualified: President-elect Joe Biden's Covid advisory board member Dr. Celine Gounder reacts to the resignation of Dr. Scott Atlas, and discusses coronavirus policies. → https://is.gd/41bH6H04:31
metreo.cases Canada04:45
Brainstormmetreo: In Canada, there have been 378139 confirmed cases (1.0% of the population) and 12130 deaths (3.2% of cases) as of 3 hours ago. 11.5 million tests were performed (3.3% positive). Fatality can be broadly expected to lie between 1.0% (assuming prevalence as in tests) and less than 3.9% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Canada for time series data.04:45
BrainstormUpdates for Belgium: +746 cases (now 577345), +98 deaths (now 16645) since a day ago05:08
CoronaBot04/r/coronavirus: Dr. Scott Atlas resigns as special adviser to Trump on coronavirus (10150 votes) | https://www.foxnews.com/politics/dr-scott-atlas-resigns-special-adviser-trump-coronavirus | https://redd.it/k48qtb05:24
BrainstormNew from The Indian Express: World: Vaccines are coming. But first, a long, dark winter in the US → https://is.gd/f1JRUY05:33
BrainstormNew from The Indian Express (Health): Health: World AIDS Day 2020: HIV AIDS care amid the COVID-19 pandemic → https://is.gd/hf1vDr06:22
BrainstormUpdates for British Columbia, Canada: +2354 cases (now 33238), +46 deaths (now 441) since 3 days ago — Nova Scotia, Canada: +48 cases (now 1305) since 4 days ago — US: +169430 cases (now 13.9 million) since 23 hours ago — Germany: +14221 cases (now 1.1 million) since a day ago07:08
BrainstormNew from r/WorldNews: worldnews: Leaked documents show China lied about Covid-19 case totals and mishandled pandemic In some instances, the number of deaths reported internally were more than double the figures released to the public... → https://is.gd/olgXpR07:11
BrainstormNew from The Indian Express: World: Pandemic fills ranks of extreme poverty worldwide → https://is.gd/0MslrE07:35
BrainstormNew from The Indian Express: World: COVID-19 drives 40% spike in number of people needing humanitarian aid, U.N. says → https://is.gd/uNkEum07:47
BrainstormUpdates for Vologda, Russia: +309 cases (now 12176), +8 deaths (now 152) since a day ago — Samara, Russia: +254 cases (now 22355), +5 deaths (now 417) since a day ago — Kirov, Russia: +242 cases (now 18059), +1 deaths (now 195) since a day ago — Kirovohrad Oblast, Ukraine: +201 cases (now 5286), +3 deaths (now 158) since a day ago08:22
BrainstormNew from The Indian Express: World: Red Cross chief urges vaccine ‘fake news’ fight → https://is.gd/En8MSk08:36
BrainstormNew from NPR: Coronavirus Was In U.S. Weeks Earlier Than Previously Known, Study Says: The discovery, uncovered after analyzing blood donations from nine states, strengthens evidence that the coronavirus was quietly spreading around the world before health officials were aware. → https://is.gd/OtKZ3e09:01
BrainstormNew from The Indian Express: World: Japan bird flu outbreak spreads to farm in fourth prefecture → https://is.gd/P1xwJz09:13
BrainstormNew from Medical Xpress: Lab results don't explain 'obesity paradox,' but bias may: Results of standard laboratory tests performed on adult outpatients to provide an overall picture of their health are fairly consistent between those with obesity and their leaner counterparts, investigators report. → https://is.gd/TgYz8H09:37
BrainstormNew from The Indian Express: World: Increase in trafficking of women, gender-based violence due to pandemic: Nobel Peace Prize winner → https://is.gd/33ADW609:50
BrainstormNew from Medical Xpress: Red Cross chief urges vaccine 'fake news' fight: The head of the world's largest humanitarian network is urging governments and institutions to combat "fake news" about COVID-19 vaccines which has become "a second pandemic" and start building trust in communities around the world about the critical importance of vaccinating people. → https://is.gd/xsTIwb10:02
BrainstormNew from BBC Health: (news): Covid vaccines: Who decides if they are safe? → https://is.gd/JgUnBt10:14
de-facto%title https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1780/600038910:15
Brainstormde-facto: From academic.oup.com: Estimated incidence of COVID-19 illness and hospitalization — United States, February–September, 2020 | Clinical Infectious Diseases | Oxford Academic10:15
de-facto"To estimate the cumulative incidence SARS-CoV-2 infections, symptomatic illnesses, and hospitalizations, we adapted a simple probabilistic multiplier model. Laboratory-confirmed case counts that were reported nationally were adjusted for sources of under-detection based on testing practices in inpatient and outpatient settings and assay sensitivity."10:16
de-facto"We estimated that through the end of September, 1 of every 2.5 (95% Uncertainty Interval (UI): 2.0–3.1) hospitalized infections and 1 of every 7.1 (95% UI: 5.8–9.0) non-hospitalized illnesses may have been nationally reported."10:16
de-facto"Applying these multipliers to reported SARS-CoV-2 cases along with data on the prevalence of asymptomatic infection from published systematic reviews, we estimate that 2.4 million hospitalizations, 44.8 million symptomatic illnesses, and 52.9 million total infections may have occurred in the U.S. population from February 27–September 30, 2020."10:16
de-factohttps://gis.cdc.gov/grasp/COVIDNet/COVID19_3.html10:18
de-facto%title10:18
Brainstormde-facto: From gis.cdc.gov: COVID-19 Hospitalizations10:18
de-factohttps://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases10:19
de-facto%title10:19
Brainstormde-facto: From covid.cdc.gov: CDC COVID Data Tracker10:19
de-facto%title https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/older-adults.html10:20
Brainstormde-facto: From www.cdc.gov: Older Adults and COVID-19 | CDC10:20
BrainstormNew from Medical Xpress: Diseases, Conditions, Syndromes: Is shopping in stores safe during the pandemic? → https://is.gd/uNHo3e10:26
de-facto"Our preliminary estimates indicate approximately 1 in 8, or 13%, of total SARS-CoV-2 infections were recognized and reported through the end of September. Similarly, a recent serologic survey of SARS-CoV-2 antibodies in 10 geographically diverse U.S. sites from March 23–May 12 of 2020 estimated that the total number of SARS-CoV-2 infections was at least 10 (range by U.S. site: 6–24) for every reported case [3], with improvements10:27
de-facto in this ratio by later time points"10:27
de-facto%cases USA10:28
Brainstormde-facto: In US, there have been 13.9 million confirmed cases (4.2% of the population) and 274332 deaths (2.0% of cases) as of 3 hours ago. 193.7 million tests were performed (7.2% positive). Fatality can be broadly expected to lie between 1.2% (assuming prevalence as in tests) and less than 3.2% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=US for time series data.10:28
de-factoso if it was like 8-fold of that it would be 13.9M*8 = 111.2M cases or 10:28
de-facto33.9% of 328M US population10:29
de-factothats crazy...10:29
de-factohence it would mean CFR = 0.274M / 13.9M =  1.9% and IFR = 0.274M / 111.2M = 0.25%10:33
BrainstormNew from Medical Xpress: Non-essential shops reopen in Belgium as virus numbers drop: Non-essential shops in Belgium were reopening Tuesday in the wake of encouraging figures about declining daily coronavirus infection rates and hospital admissions. → https://is.gd/pXGTbJ10:39
BrainstormNew from CNBC Health: One chart shows how bad Germany's second wave of the coronavirus is: Germany was widely seen as a poster-child for its approach to tackling the coronavirus in the spring, but its second wave is proving more deadly. → https://is.gd/02IOLv10:51
de-facto%title https://www.dhs.gov/sites/default/files/publications/mql_sars-cov-2_-_cleared_for_public_release_20201117.pdf11:26
Brainstormde-facto, the URL could not be loaded 11:27
de-factooh it surely can be loaded11:28
de-facto"Based on experimental studies with humans exposed to other coronaviruses and animals exposed to SARS-CoV-2,11:28
de-factothe dose at which 50% of humans become infected is likely between 10 and 1,000 plaque-forming units (PFU). "11:28
de-facto"Exhaled breath may emit 10^5-10^7 genome copies per person per hour; the amount of infectious virus remains unknown."11:33
BrainstormUpdates for Azerbaijan: +6385 cases (now 125602), +62 deaths (now 1433) since 20 hours ago — Switzerland: +146 deaths (now 4851) since 23 hours ago11:36
de-facto"Meta-analysis indicates that approximately 18% of household contacts of infected index patients acquire SARS-CoV-2 (i.e. the "attack rate"), with higher attack rates for symptomatic index cases, spouses of index cases, and adults. In the US, symptomatic index cases resulted in transmission to approximately 53% of household members, regardless of index patient age. This is higher than prior estimates, likely due to intense follow-up 11:40
de-factoreporting. 75% of household infections occurred within 5 days of illness onset in the index case. Attack rates are lower for non-household contacts."11:40
de-factoHence its urgently essential to ensure enough air exchange...11:41
de-facto...not by recirculation but by replacing with fresh air from outdoors, even if its cold.11:42
generazählen die Kanonenboote als householdcontact ))11:42
generaso, the pupils are either going to freeze or to get infected11:43
de-factodont get me ranting about schools again, in my opinion its a mistake that they are kept open.11:47
BrainstormNew from Medical Xpress: BioNTech, Pfizer ask Europe to OK vaccine for emergency use: The German pharmaceutical company BioNTech and its U.S. partner Pfizer say they have submitted an application for conditional approval of their coronavirus vaccine with the European Medicines Agency. → https://is.gd/YL4xMb11:53
BrainstormNew from EMA: What's new: General: COVID-19: latest updates → https://is.gd/ejWHzQ12:05
BrainstormNew from CNBC Health: Pfizer, BioNTech apply for coronavirus vaccine approval in Europe: If authorization is granted, it could potentially enable use of the vaccine in Europe before the end of 2020, BioNTech said in a press release. → https://is.gd/JpjiC212:18
BrainstormNew from ECDC: Download the daily number of new reported cases of COVID-19 by country worldwide: The downloadable data file is updated daily and contains the latest available public data on COVID-19. You may use the data in line with ECDC’s copyright policy. → https://is.gd/zYsz7d12:30
BrainstormUpdates for Palestine: +2357 cases (now 88004), +15 deaths (now 747) since 23 hours ago — Germany: +13584 cases (now 1.1 million), +343 deaths (now 16903) since a day ago12:50
BrainstormNew from Scientific American: Health: World AIDS Day Is a Grim Reminder That We Have Many Pandemics Going On → https://is.gd/SHZcBE13:07
BrainstormNew from BMJ: Covid-19: Asymptomatic cases may not be infectious, Wuhan study indicates: A mass screening programme of more than 10 million residents of Wuhan, China, performed after SARS-CoV-2 was brought under control, has identified 300 asymptomatic cases of covid-19, none of which... → https://is.gd/edzBJR13:31
BrainstormNew from CNBC Health: Pfizer, BioNTech apply for Covid vaccine approval in Europe: If authorization is granted, it could enable use of the vaccine in Europe this month, BioNTech said. → https://is.gd/JpjiC213:43
BrainstormUpdates for US: +168851 cases (now 13.9 million), +1242 deaths (now 274355) since 23 hours ago14:07
BrainstormNew from Medical Xpress: European regulator to decide Dec. 29 on 1st virus vaccine: The European Medicines Agency will convene a meeting on Dec. 29 to decide if there is enough data about the safety and efficacy of the COVID-19 vaccine developed by Pfizer and BioNTech for it to be approved, the regulator said Tuesday. → https://is.gd/7tAYs414:08
BrainstormNew from Medical Xpress: Hidden damage to lungs from COVID-19 revealed in new study: Research by the University of Sheffield, in collaboration with the University of Oxford, is the first in Europe to use hyperpolarised xenon gas with MRI scanning to identify the impact on lung function as patients recover from COVID-19, when standard MR and CT scans [... want %more?] → https://is.gd/EPY7eZ14:20
BrainstormNew from Medical Xpress: Pets, touch and COVID-19: Why our furry friends are lifesavers: Lockdowns, job losses and social isolation have been the hallmarks of 2020 as COVID-19 tightens its grip on the world, not only infecting millions and leaving a mounting death toll, but also denying humans the most basic sense—touch. → https://is.gd/0C6YxD14:33
BrainstormUpdates for Sweden: +17629 cases (now 260758), +117 deaths (now 6798) since 4 days ago14:36
BrainstormNew from r/Coronavirus: Coronavirus: Daily Discussion Post - December 01 | Questions, images, videos, comments, unconfirmed reports, theories, suggestions → https://is.gd/MO2DCu14:58
BrainstormNew from NIH Director's blog: Vast Majority of Pregnant Women with COVID-19 Won’t Have Complications, Study Finds: It’s natural and highly appropriate for women to be concerned about their health and the wellbeing of their unborn babies during pregnancy. With the outbreak of the pandemic, those concerns have only increased, especially after a study [... want %more?] → https://is.gd/vWuZkH15:11
BrainstormNew from WHO Euro: Staying safe and healthy this winter: The winter holidays this year might be different from recent years due to the COVID-19 pandemic. But the best gifts you can give are health, kindness and support. → https://is.gd/15cWOc15:23
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Serum Institute threatens to sue Covid-19 vaccine trial participant; U.S. agency prepares for Covid-19 vaccine fraud → https://is.gd/bnuoaz15:35
BrainstormNew from EMA: What's new: Medicine: Veterinary medicines European public assessment report (EPAR): Purevax RCPCh FeLV, vaccine against feline viral rhinotracheitis, feline calicivirosis, feline panleucopenia, feline leukeamia and feline Chlamydophila infections, Date of authorisation: 23/02/2005, Revision: 13, Status: Authorised → https://is.gd/VArGhL15:48
BrainstormNew from Medical Xpress: Why long-suffering hosts grow a thick skin: Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD). Occurring commonly after bone marrow or stem cell transplants performed to treat some blood [... want %more?] → https://is.gd/AxYArn16:01
CoronaBot04/r/covid19: Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site (84 votes) | https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1781551 | https://redd.it/k4jzd416:11
BrainstormNew from Medical Xpress: Researchers track connections between COVID-19 health behaviors and experiences of people of color: Everyone in the world is facing the challenges and changes presented by the COVID-19 pandemic. But people of color may face additional barriers to staying healthy. → https://is.gd/qaZeLg16:13
BrainstormUpdates for Serbia: +7999 cases (now 183437), +48 deaths (now 1652) since a day ago16:21
BrainstormNew from The Indian Express (Health): Life-style: Get glowing, nourished and brighter skin with this organic face mask → https://is.gd/IfmuaD16:26
BrainstormNew from Medical Xpress: France plans widespread Covid vaccinations in April-June: France is aiming to launch a widespread COVID-19 vaccination campaign between April and June next year, President Emmanuel Macron said Tuesday. → https://is.gd/jEcqLe16:38
BrainstormUpdates for Canada: +5795 cases (now 379846), +61 deaths (now 12137) since 19 hours ago16:50
BrainstormNew from WHO Euro: Delivering good mental health for people living with HIV: This World AIDS Day let’s take stock of progress made and reflect on what we have learned. 2020 has not been an easy year for anyone amid the disruption and devastation brought by COVID-19. → https://is.gd/55DAof16:50
BrainstormNew from Medical Xpress: Out of many COVID-19 tests, which one to choose?: Until a vaccine is available, curbing the coronavirus pandemic relies heavily on how quickly a potentially exposed individual can be tested and quarantined. However, the current diagnostic techniques vary in reliability and relevance, so an understanding of which test is most [... want %more?] → https://is.gd/hQ0MZU17:03
BrainstormNew from ClinicalTrials.gov: (news): Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome → https://is.gd/oyQPrp17:16
BrainstormUpdates for United Kingdom: +3821 cases (now 1.6 million), +184 deaths (now 58681) since 9 hours ago — Maine, US: +219 cases (now 11976), +20 deaths (now 214) since a day ago17:21
Jigsy13,430K cases today, 603 deaths...17:27
Jigsy...and the lockdown ends tomorrow.17:27
euod[m]in the UK?17:28
JigsyYeah.17:34
JigsyGuessing that'll spike up again over the week.17:34
JigsyAs people will be like "Psh, who cares? We have a vaccine now!"17:34
BrainstormUpdates for Italy: +19347 cases (now 1.6 million), +785 deaths (now 56361) since a day ago17:35
BrainstormNew from ClinicalTrials.gov: (news): Silent Hypoxia and Awake Proning in COVID-19 Patients → https://is.gd/wQLgeu17:40
BrainstormNew from ClinicalTrials.gov: (news): Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome → https://is.gd/oyQPrp17:53
BrainstormNew from ClinicalTrials.gov: (news): Silent Hypoxia and Awake Proning in COVID-19 Patients → https://is.gd/wQLgeu18:06
LjLuhm18:06
LjLi'm not sure why Brainstorm said only data "since 9 hours ago" for the UK18:06
LjLit did that before though18:06
BrainstormUpdates for Uganda: +576 cases (now 21035) since 22 hours ago18:35
BrainstormNew from CNBC Health: Trump Covid vaccine chief Slaoui says everyone in U.S. could be immunized by June: If enough people get immunized, the U.S. pandemic could be under control in the second half of 2021, the Trump administration's Covid vaccine chief said. → https://is.gd/svDeue18:42
LjLgood lord, r/covid19 is strict in ways perhaps it shouldn't be18:43
LjLde-facto, euod[m]: i eventually made the chinese paper appear in anonymous file sharing sites, so that the url it comes from wouldn't show up, but look at the thread https://www.reddit.com/r/COVID19/comments/k2doss/the_early_cryptic_transmission_and_evolution_of/ my comments about it have been deleted, i only see a "Not a proper source" comment from a moderator (not sure if Reddit is confusing, or these moderators are confusing: my comments appear to have 18:44
LjLbeen "shadow-removed"...? because i can still see them myself, as if nothing happened, but not from a private window), and all of that has been locked with no possibility to comment further, like saying "okay, sorry, would archive.org be a proper source?" - nope can't even say that18:44
LjLalthough i'm sure the answer would be that it wouldn't, anyway, since it's archive.org/.is pointing to a random greek news site that's not where the paper originally was18:45
snakeLjL, is it the reddit hivemind?18:45
snakethey don't like free-thinkers18:45
LjLit's individual moderators so no i wouldn't say so18:46
BrainstormNew from CNBC Health: (news): White House summons FDA chief Stephen Hahn to discuss why agency isn't moving faster on Covid vaccine → https://is.gd/vssc9z18:55
generayup! they could have imported the vazzine vrom russia or kina!19:03
BrainstormUpdates for Arizona, US: +10322 cases (now 337139), +48 deaths (now 6687) since a day ago19:07
BrainstormNew from Medical Xpress: Meningococcus B vaccine prevents disease with 79 per cent effectiveness in under-18s: Meningococcus group B, the most prevalent strain of meningococcal infection, is prevented with 79 per cent effectiveness in children and young adults inoculated with the 4CMenB vaccine, also known as Bexsero, according to a new collaborative [... want %more?] → https://is.gd/1rm1EP19:07
LjLyikes arizona19:08
BrainstormNew from Medical Xpress: Coronavirus dreams: how anger, sadness and fear crept in during lockdown—new research: The COVID-19 pandemic has changed nearly every aspect of our lives. Our dreams are no different. Soon after the first lockdowns started, people reported having more dreams than before, with different content. This was explained by the fact [... want %more?] → https://is.gd/2RVWZP19:20
BrainstormUpdates for Louisiana, US: +5326 cases (now 237740), +35 deaths (now 6455) since a day ago19:21
LjLwell, here's what i wrote to the subreddit mods, and here's what they replied: https://paste.ee/p/ypR7l#SJNhKxKH0AhatcS03427f375CbL5fXc319:32
BrainstormNew from Medical Xpress: Chilblain-like lesions during COVID-19 tied to type I interferonopathy: (HealthDay)—Patients presenting with chilblain-like lesions during the COVID-19 pandemic have histologic and biologic patterns of type I interferonopathy, according to a study published online Nov. 25 in JAMA Dermatology. → https://is.gd/lOonZp19:32
generathat pastebin doesnt work for me19:38
BrainstormNew from Medical Xpress: Conversational assistants could be used to improve African American health around COVID-19: University of Michigan researchers say employing a conversational assistant—think 'Hey, Siri,' or perhaps something less global like an "Ask the Doc"—could be one way to narrow the gap in health disparities impacting the African [... want %more?] → https://is.gd/L0U9Lo19:45
hirogenwhy is you don't hear much about Africa and Covid?19:51
hirogenyet black ppl are more prone to it in the West?19:51
LjLbecause people there barely get tested, i suspect19:55
LjLalso, maybe on a brighter note, they tend to be younger (well, not so much a bright note, since that means they tend to die young)19:55
LjLso there might be fewer elderly who get severe cases19:55
tinwhiskersYes, other than South Africa, they are doing quite well. There's some murmurings about a widespread vaccination they have there that may have given some protection, but also what LjL says.19:56
tinwhiskersI'm thinking HPV but have a feeling it's another one.19:57
BrainstormNew from Medical Xpress: Which Americans will get the COVID vaccine first?: The Pfizer and Moderna COVID vaccines could be approved in a matter of weeks, but who in the United States will get them first? → https://is.gd/xQWZTm19:57
LjLtinwhiskers, i think people here are widely vaccinated against HPV... only younger people, but, older people almost certainly have HPV so it makes no sense to vaccinate them20:00
tinwhiskersYeah, well, as I say, I think it might have been another one but it isn't springing to mind. Do you recall the widespread speculation about cross-protection from *some* other vaccine for covid?20:03
tinwhiskersOh, BCG20:05
tinwhiskersSo it's been speculated that the BCG vaccine is giving some cross protection and given it's so widely used in Africa that *may* partially explain the low rates.20:07
CoronaBot04/r/coronavirus: Comedian began chronicling his COVID-19 ‘journey’ online. He died two days later (10018 votes) | https://www.sacbee.com/news/coronavirus/article247511390.html | https://redd.it/k4jeih20:07
LjL%wik BCG vaccine20:08
BrainstormLjL, from English Wikipedia: Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). In countries where tuberculosis or leprosy is common, one dose is recommended in healthy babies as close to the time of birth as possible. In areas where tuberculosis is not common, only children at high risk are [... want %more?] → https://en.wikipedia.org/wiki/BCG_vaccine20:08
LjLUse of the BCG vaccine may provide protection against COVID‑19.[103][104]However, epidemiologic observations in this respect are ambiguous.[105]20:09
LjLAs of March 2020, while it is not known if the tuberculosis vaccine protects against COVID-19, it has been suggested for study.[106][107][108] Spanish, French, German and Dutch research entities are preparing trials using genetically-modified BCG vaccines.[109] BCG vaccine is in phase III trials in health care workers in Australia and Netherlands.[110] BCG vaccine is being evaluated in Greece[111] and Poland. Polish scientists are investigating[when?] 20:09
LjLwhether the BCG vaccine has an immune training effect.[112]20:09
LjLThe WHO does not recommend its use for prevention as of 13 April 2020.[113] 20:09
LjLuhm20:09
tinwhiskersRight. It *may* explain it.20:09
LjLtinwhiskers, look at this https://en.wikipedia.org/wiki/BCG_vaccine#Europe20:09
LjLItaly and Belgium are the very few European countries where it was *never* mandatory20:09
BrainstormNew from Medical Xpress: COVID-19 hospitalizations in U.S. hit record high: (HealthDay)—Yet another grim record for COVID-19 hospitalizations was set on Monday, as more than 96,000 patients battled severe cases of the virus in hospital wards across America. → https://is.gd/DTnuIK20:10
LjLand they are also the countries where COVID did the most damage20:10
LjLother countries where it stopped being mandatory a long time ago ('80s): Spain, Sweden20:10
tinwhiskersAlso in Africa you've got some very hot dry conditions, which could also contribute20:10
LjLthis may be all just a coincidence but it's rather striking20:11
tinwhiskersYeah, so some studies showing a link and some not showing a link. The jury is out so nobody is recommending anything as radical as taking the BCG vaccine for covid protection.20:13
BrainstormUpdates for Switzerland: +93 deaths (now 4908) since 20 hours ago20:21
BrainstormNew from Medical Xpress: EU plans vaccines as regulator sets approval deadline: European countries were given a clear timeframe for the start of their vaccination programmes on Tuesday after the bloc's medicines regulator said it will decide by December 29 whether to grant emergency approval for the first COVID-19 jabs. → https://is.gd/vRNLUu20:34
BrainstormNew from CNBC Health: Trump Covid vaccine chief Slaoui says everyone in U.S. could be immunized by June: If enough people get immunized, the U.S. pandemic could be under control in the second half of 2021, the Trump administration's Covid vaccine chief said. → https://is.gd/svDeue20:59
LjLtinwhiskers, do you know if the BCG vaccine is kinda side effectey?21:03
LjLi didn't look at the studies it. it just really struck me that Belgium and Italy stand out as the countries where it was never mandatory21:03
LjLbut my parent say tubercolosis vaccination *was* mandatory21:03
LjLso i guess we were using a different vaccine?21:03
LjL%tr <it Il Vaccino Diffondente Salvioli (sigla VDS) è stato, dal 1948 fino al 1976, un vaccino italiano contro la tubercolosi. Era preparato dal professor Gaetano Salvioli (Modena 1894- Bologna 1982) dell’Università di Bologna. Il VDS fu per alcuni decenni il concorrente italiano del vaccino anti tubercolare francese BCG (bacillo di Calmette e Guérin).21:04
BrainstormLjL, Italian to English: The Vaccino Diffondente Salvioli (acronym VDS) was, from 1948 until 1976, an Italian vaccine against tuberculosis. It was prepared by Professor Gaetano Salvioli (Modena 1894 - Bologna 1982) of the University of Bologna. The VDS was for some decades the Italian competitor of the French anti-tuberculous vaccine BCG (bacillus of Calmette and Guérin). [... want %more?]21:04
LjLhttps://en.wikipedia.org/wiki/Salvioli%27s_diffusing_vaccine21:04
BrainstormUpdates for Delaware, US: +689 cases (now 36343), +5 deaths (now 777) since a day ago21:07
tinwhiskersLjL: No, I don't really know anything about it other than that I'd seen it mentioned in covid-related news, and with specific regard to Africa maybe having lower covid rates partly due to it.21:10
LjLtinwhiskers, it can leave scars apparently21:11
BrainstormNew from "COVID-19 pandemic in Denmark" on Wikipedia: Pardy: /* Statistics */: Statistics ← Previous revision Revision as of 20:03, 1 December 2020 Line 217: Line 217: {{Graph:Chart {{Graph:Chart |type=rect |type=rect − |width= 2500 + |width= 3000 |height= |height= |colors=#F46D43 |colors=#F46D43 Line 224: Line 224: |xAxisAngle=-60 |xAxisAngle=-60 [... want %more?] → https://is.gd/58UIK321:11
tinwhiskersOh. Right. One of those vaccines. Badge of honor.21:11
LjLthe main difference seems to be that the italian version is made with human tubercolosis bacteria attenuated by heat21:12
LjLBCG is is made with bovine tubercolosis, attenuated in some other way21:12
LjLalthough the italian one also contains a smaller amount of bovine21:12
LjLso i guess it's a bit more complicated a vaccine21:12
LjLwould be interesting to know if Belgium didn't use BCG because it also used VDS21:13
LjLbut Wikipedia doesn't say that21:13
ubLIX[m]everyone my age had BCG 30 years ago21:14
ubLIX[m]with a prior test to establish suitability for vaccine21:14
ubLIX[m]left scar, no other side effects21:14
ubLIX[m]*everyone at my school21:15
ubLIX[m]i assume this was true all over the UK21:15
tinwhiskersclearly didn't stop covid there :-/21:16
ubLIX[m]mhm :\21:16
ubLIX[m]apparently this blanket vaccination at school age stopped in the UK in 200521:21
BrainstormUpdates for France: +288 deaths (now 53019) since 20 hours ago — Netherlands: +4236 cases (now 529002) since 23 hours ago21:21
BrainstormNew from Medical Xpress: Alcohol-free hand sanitizer just as effective against COVID as alcohol-based versions: A new study from researchers at Brigham Young University finds that alcohol-free hand sanitizer is just as effective at disinfecting surfaces from the COVID-19 virus as alcohol-based products. → https://is.gd/idmarT21:23
BrainstormUpdates for Spain: +8257 cases (now 1.7 million), +442 deaths (now 45511) since a day ago21:35
BrainstormNew from Medical Xpress: US scientists developing nasal spray to prevent COVID-19: Scientists at the University of Pennsylvania and the biotech firm Regeneron are investigating whether technology developed for gene therapy can be used to make a nasal spray that will prevent infection with the new coronavirus. → https://is.gd/EweN1U21:36
BrainstormNew from Medical Xpress: US panel to decide who should get the first COVID-19 shots: An influential government advisory panel convened on Tuesday to answer one of the most pressing questions in the U.S. coronavirus outbreak: Who should be at the front of the line when the first vaccine shots become available? → https://is.gd/1XGO4p21:48
BrainstormNew from PLOS ONE: Geographical and social isolation drive the evolution of Austronesian languages: by Cecilia Padilla-Iglesias, Erik Gjesfjeld, Lucio Vinicius The origins of linguistic diversity remain controversial. Studies disagree on whether group features such as population size or social structure accelerate or decelerate linguistic [... want %more?] → https://is.gd/4MupBE22:00
DocScrutinizer05moin!22:12
BrainstormNew from PLOS ONE: Epidemiology and pathological progression of erythematous lip lesions in captive sun bears ( Helarctos malayanus ): by Kirsty Officer, Mathieu Pruvot, Paul Horwood, Daniela Denk, Kris Warren, Vibol Hul, Nhim Thy, Nev Broadis, Philippe Dussart, Bethany Jackson This study investigates the occurrence of erythematous lip lesions in a [... want %more?] → https://is.gd/K2SD1N22:13
BrainstormNew from PLOS ONE: Core warming of coronavirus disease 2019 (COVID-19) patients undergoing mechanical ventilation—A protocol for a randomized controlled pilot study: by Nathaniel Bonfanti, Emily Gundert, Anne M. Drewry, Kristina Goff, Roger Bedimo, Erik Kulstad Background Coronavirus disease 2019 (COVID-19), caused by the virus SARS-CoV-2, is [... want %more?] → https://is.gd/Cltq0O22:25
de-facto[m]So now both, Moderna and BioNTech/Pfizer formally asked for certification of their vaccine in EU22:38
de-facto[m]Does that mean that their phase III trials data is complete for conclusion and already given to the certification administrations?22:39
de-facto[m]or complete enough? asking because i am looking forward to seeing the data published in a paper ... patiently waiting for that :)22:40
LjLde-facto[m], i don't know. maybe it means as little as that they've reached a confidence interval where they're certain the vaccine is both safe and at least >50% (which is a far cry from what we actually expect, so it should be easy to claim that)22:40
LjLde-facto[m], in Moderna's latest press release they sort of stress that their study will be published soon. they don't say "the study will be published soon", i'm sort of inferring22:40
LjLwhat annoys me is that Moderna seems by far the best candidate to me, but the EU only ordered 80 million doses while they ordered 300 million of other major vaccines (each)22:41
de-facto[m]even if we may see a certification in mid of December or such in EU, i doubt that significant deliveries will be given to EU from Moderna this year still22:42
LjLmeanwhile from ##science <CarlSagan> [NYT - Science] Virus May Have Arrived in U.S. in December, but Didn’t Spread Until Later https://www.nytimes.com/2020/12/01/health/coronavirus-december-arrival.html 2020-12-01T21:20:2722:42
de-facto[m]afaik EU ordered 160M doses, but they probably will deliver to "America first"22:42
LjLde-facto[m], oh that's extremely unlikely, they aren't producing very many doses, reddit or somewhere was talking about how mRNA vaccines are very tricky to produce22:42
LjLde-facto[m], well maybe the number i've seen was 80 as in, 80 million people can get the vaccine (two doses each)22:43
de-facto[m]so the vaccine we might see here this year is the Pfizer/BioNTech one since that will be produced in Belgium and Germany afaik22:43
LjLi assume it was consistent with the other numbers though22:43
LjLunless TV was stupid22:43
LjLde-facto[m], yes, that's still a better shot than Oxford22:43
de-facto[m]so if they really do manage to produce like 50M doses in 2020, and maybe 20M doses will go to USA, then there might be 30M doses left for the rest of the world, including EU22:43
LjLi'd hope to get Pfizer and not Oxford myself, based on what i know for now22:43
de-facto[m]and then as you told two doses are required for each immunity produced, so in 2020 it wont be so many that can aquire that22:45
de-facto[m]i guess it only will be available for the most high risk groups in elderly homes and maybe their medical personal or such22:47
de-facto[m]yet then i dont understand why they are building those vaccination centers, well maybe for cold storage in the delivery chain, but they would need teams to go from such centers into the elderly homes to give them the vaccine 22:48
de-facto[m]%title https://www.ema.europa.eu/en/news/ema-receives-application-conditional-marketing-authorisation-moderna-covid-19-vaccine22:50
Brainstormde-facto[m]: From www.ema.europa.eu: EMA receives application for conditional marketing authorisation of Moderna COVID-19 vaccine | European Medicines Agency22:50
de-facto[m]%title https://www.ema.europa.eu/en/news/ema-receives-application-conditional-marketing-authorisation-covid-19-mrna-vaccine-bnt162b222:51
Brainstormde-facto[m]: From www.ema.europa.eu: EMA receives application for conditional marketing authorisation of COVID-19 mRNA vaccine BNT162b2 | European Medicines Agency22:51
LjLuhm22:51
LjLthe bot should provide a feed from EMA :\22:51
de-facto[m]%title https://www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-covid-19/treatments-vaccines-covid-19#medicines-undergoing-evaluation-section22:52
Brainstormde-facto[m]: From www.ema.europa.eu: Treatments and vaccines for COVID-19 | European Medicines Agency22:52
BrainstormUpdates for New Hampshire, US: +772 cases (now 21766), +2 deaths (now 528) since 21 hours ago — Niger: +38 cases (now 1586), +3 deaths (now 75) since 20 hours ago — Switzerland: +117 deaths (now 4932) since 23 hours ago22:53
de-facto[m]%title https://covidvax.org/covid19-vaccines-distribution22:54
Brainstormde-facto[m]: From covidvax.org: COVID-19 vaccine: When will it be available?22:54
de-facto[m]https://translate.google.com/translate?sl=auto&tl=en&u=https://ec.europa.eu/germany/news/20201201-covid-19-impfstoffe-so-geht-es-weiter_de22:59
CoronaBot04/r/covid19: Coronavirus (COVID-19) Update: FDA Announces Advisory Committee Meeting to Discuss Second COVID-19 Vaccine Candidate (81 votes) | https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-announces-advisory-committee-meeting-discuss-second-covid-19-vaccine | https://redd.it/k4ounk23:08
BrainstormNew from CNBC Health: Trump Covid vaccine czar says side effects 'significantly noticeable' in 10% to 15% of recipients: Trump's Covid vaccine czar said Pfizer's and Moderna's vaccines are safe, with only 10% to 15% of volunteers reporting "significantly noticeable" side effects. → https://is.gd/4dJqCr23:27
BrainstormNew from CNBC Health: CDC panel says health workers, nursing homes will get Covid vaccine first: A CDC panel voted 13-1 to give health workers and long-term care facility residents the first Covid-19 vaccine doses once it's cleared for public use. → https://is.gd/W9WUpW23:39

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