libera/##covid-19/ Monday, 2020-12-28

BrainstormUpdates for Netherlands: +6689 cases (now 763627), +15 deaths (now 11019) since 21 hours ago — Canada: +9281 cases (now 551540), +163 deaths (now 14963) since 6 hours ago00:18
BrainstormUpdates for Uruguay: +510 cases (now 16728), +11 deaths (now 158) since 21 hours ago00:25
BrainstormNew from r/WorldNews: worldnews: Excess use of antibiotics due to COVID-19 triggers 'super gonorrhea' → https://is.gd/vojiGP00:48
de-factowhat is this one here? https://mednet-communities.net/inn/db/media/docs/11392.doc01:19
BrainstormNew from r/WorldNews: worldnews: 'Super Gonorrhea' on the Rise Due to COVID-19, WHO Says → https://is.gd/VIg4eU01:25
BrainstormUpdates for Afghanistan: +645 cases (now 52007), +24 deaths (now 2170) since 17 hours ago — France: +5184 cases (now 2.6 million) since 22 hours ago01:27
CoronaBot04/r/covid19: Reader response: Loss of smell in COVID-19 patients: MRI data reveals a transient edema of the olfactory clefts (80 votes) | https://n.neurology.org/content/reader-response-loss-smell-covid-19-patients-mri-data-reveals-transient-edema-olfactory | https://redd.it/kl9t8t01:53
BrainstormNew from r/WorldNews: worldnews: Zhang Zhan chronicled China’s COVID-19 crisis. Now she is accused of spreading lies → https://is.gd/VigFvX02:02
de-factotitle https://ourworldindata.org/covid-vaccinations02:16
de-facto.title https://ourworldindata.org/covid-vaccinations02:16
Brainstormde-facto: From ourworldindata.org: Coronavirus (COVID-19) Vaccinations - Statistics and Research - Our World in Data02:16
CoronaBot04/r/covid19: Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases (82 votes) | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246018/#__ffn_sectitle | https://redd.it/kl6rxu02:17
de-factough02:22
LjL"Important to note is that vaccine trials exclude those who have autoimmune diseases so we really have no idea how the vaccine will affect those who have the highest chance of this happening to them." ugh indeed :\02:44
LjLif ryouma were here he'd "ugh" for half an hour02:44
LjLhe wouldn't be wrong02:44
BrainstormNew from r/WorldNews: worldnews: The new variant of COVID-19 first discovered in the UK has been found in a patient in Australia → https://is.gd/pF8evX03:18
KREYREENIs there any Vitamine D that i can dissolve in a water and left it there for around 10 hours?03:25
BrainstormUpdates for Netherlands: +6811 cases (now 766217), +21 deaths (now 11037) since 19 hours ago — France: +6617 cases (now 2.6 million), +129 deaths (now 62763) since 19 hours ago — Canada: +9761 cases (now 552020) since 9 hours ago — Switzerland: +1 deaths (now 7210) since 9 hours ago03:30
LjLKREYREEN, i've always read that vitamin D should be taken with fats to maximize absorption03:36
LjLsometimes it is *provided* in fat (oil)03:36
LjLwhen it isn't, it's often recommended to take it with some kind of fats03:37
LjLso i think water may be a suboptimal way to take it03:37
KREYREENLjL, i read the same thing was thinking about it incase in something that doesn't dissolve in water (tea), but dissolves in a stomach while it being encased in a fat?03:37
LjLi don't really know the mechanism to be honest03:38
KREYREENneither do i x.x03:38
KREYREENi guess it would be more comfortable to get a light and let it shine on me cute skin~03:38
KREYREENbut i dunno the light frequency for that O.o03:38
LjLthat might have to be one heck of a ligh :P03:38
LjLand that too03:39
KREYREENlike they have these solariums that only use those energy efficient white things03:39
LjLthere are some very bright lights that are sometimes used for sleep therapy, to "reset" people's biological clocks03:39
KREYREENO.O03:39
LjLbut that's a different purpose, so i have no idea if they make the body produce vitamin D03:39
KREYREENyou can do that with light?!03:39
LjLi just know they're very bright. also, they're probably only safe in a medical setting03:39
LjLKREYREEN, it can help. if your body thinks the sun is suddenly shining outside, then even if it's not, it's a cue that it's daytime03:40
KREYREENO.O03:40
KREYREENinteresting03:40
LjLKREYREEN, did you know that if someone is blind, depending on the type of blindness, they may or may not "automatically" develop sleep disorders? because in some cases, if the eyes are still physically working, they can still sense light and darkness and that gets used by the body, even though they can't actually "see" anything, because the pathway used for determining night vs day is different from wherever the optical nerve goes03:41
KREYREENinteresting o.o03:41
KREYREENLjL, don't you know if blue light is any relevant to that? I remember doctors keep saying something along these lines only for other doctors say that it's bs >.>03:42
KREYREEN*pandemic03:43
LjLKREYREEN, i am not really sure. i know that non-red light (and blue is as far from red as it gets) is most likely to disrupt rods, in other words night vision. so for example if your eyes are currently dark-adapted because you're doing astronomy or something, and you want to be able to see something, using a red light helps avoid losing the dark-adaptation. using a blue light would be worst03:44
LjLin addition to that, the "whiteness" of the sun contains a lot more blue light during daytime than during dusk or dawn03:44
LjLwhich you can see by the sun turning orange-reddish when it sets03:44
LjLit is easy to assume that the body does take that as a cue to tell it "which time it is"03:44
KREYREENinteresting O.o03:44
LjLbut even though it's easy to assume, i don't have a handy link to a study that proves it :P03:45
LjLi presume you know that programs like f.lux have become so ubiquitous that now operating systems tend to just include that functionality03:45
chungI don't know how to talk to CovBot, esp. the number of new patients each day for my location. Is there anyway? Thanks,03:45
LjLi am wary of fads, but i don't think this is just a fad03:46
KREYREENLjL, yep but i found that being too annoying for me and i just lowered the brightness o.o03:46
KREYREENwhich seems to have similar effect03:46
LjLchung, i don't run CovBot, i run Brainstorm so i can answer for Brainstorm and unfortunately, no, there is no way to get the daily number. it posts it when it obtains it, for select countries (or for countries where it's big)03:46
LjLKREYREEN, well, lowering the brightness so that it's appropriate to the environment is definitely something you should do in general, but it's not quite the same effect03:47
LjLKREYREEN, if you found it too annoying, it might have been set to an excessive "redness". you could try with a higher white temperature03:47
KREYREENHm true O.o will research03:48
LjLKREYREEN, ideally, the light from your screen should match the light from your environment. which means... if it's sunny outside and it comes through the window, it should match the sun's temperature (presumably a "cold" white during daytime), while if it's dawn or dusk or you're using artificial lighting, it should match the color temperature of that lighting, which is often 2700K to 3000K unless you have "cold" lamps03:49
LjL%cases thailand03:49
BrainstormLjL: In Thailand, there have been 6123 confirmed cases (0.0% of the population) and 60 deaths (1.0% of cases) as of 20 hours ago. 1.3 million tests were performed (0.5% positive). See https://offloop.net/covid19/?default=Thailand for time series data.03:49
KREYREENHm i see O.o03:49
KREYREEN%newzealand03:50
KREYREEN%zeland03:50
KREYREENah03:50
KREYREEN%cases newzealand03:50
chungLjL: Thanks, I shall also try Brainstorm.03:50
BrainstormKREYREEN: Sorry, newzealand not found. Either there aren't cases, or it's under a different name.03:50
KREYREENx.x03:50
KREYREEN%cases new zealand03:50
BrainstormKREYREEN: In New Zealand, there have been 2144 confirmed cases (0.0% of the population) and 25 deaths (1.2% of cases) as of 22 hours ago. 1.4 million tests were performed (0.2% positive). Fatality can be broadly expected to lie between 0.3% (assuming prevalence as in tests) and less than 1.2% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=New%20Zealand for time series data.03:50
KREYREENyay~03:50
KREYREEN>  (0.0% of the population)03:51
LjLKREYREEN, basically, aside from the presumed health benefit, what your eyes perceive as "white" is whatever the current light source is. that's true for reflective objects: like, a "white" sheet of paper will reflect the color of your current light source. but with computers/phones, the screen itself is a light source, so if it has its own white point, there can be a mismatch. this is not about health, it's simply about working with light03:51
chung%cases beijing03:51
Brainstormchung: In Beijing, China, there have been 971 confirmed cases (0.0% of the population) and 9 deaths (0.9% of cases) as of 20 hours ago. Fatality can be broadly expected to lie between 0.3% (assuming deaths/cases with ⅔ undetected) and less than 0.9% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Beijing for time series data.03:51
LjLsub-regions are available for some countries, but not all03:51
LjLgenerally, city or county data are not available03:51
KREYREEN>  and 25 deaths (1.2% of cases) | don't the have 5M people there? Or are they murdering the infected to keep the numbers down as Spitting Image said? O.o03:51
LjLi could and probably should provide something for daily new cases... but the code is a mess and so far i haven't :\03:51
KREYREENLjL, like using orang-y light from a lamp and then white light from a monitor is harmful?03:52
LjLKREYREEN, 25 deaths is 1.2% of 2144 (which is the cases)03:52
KREYREENah i see 03:53
gigasu_shidahey ljl how's lombardia coping?03:53
chungLjL: which symbol seperates region and sub-region?03:53
LjLKREYREEN, no, as i said, this is not about the health aspect per se. it's not necessarily "harmful", it's just... wrong. if you were editing images, you'd edit them wrong. if you *aren't* editing images, it probably still feels wrong to your brain to some extent03:53
chung%cases china;wuhan03:53
Brainstormchung: Sorry, china;wuhan not found. Either there aren't cases, or it's under a different name.03:53
KREYREENO.o03:53
chung%cases china,wuhan03:54
Brainstormchung: Sorry, china,wuhan not found. Either there aren't cases, or it's under a different name.03:54
LjLchung, there is no distinction between region and sub-region. by "sub-region" i only meant whatever is smaller than the country. so Beijing is the sub-region, and China is the country. that's all i have i'm afraid03:54
LjLchung, oh, that, no, you just type the region name without the country03:54
LjL%cases Hubei03:54
BrainstormLjL: In Hubei, China, there have been 68149 confirmed cases (0.1% of the population) and 4512 deaths (6.6% of cases) as of 24 days ago. Fatality can be broadly expected to lie between 2.2% (assuming deaths/cases with ⅔ undetected) and less than 6.5% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Hubei for time series data.03:54
chung%cases wuhan03:54
Brainstormchung: Sorry, wuhan not found. Either there aren't cases, or it's under a different name.03:54
LjLWuhan is a city and i don't think it's listed03:54
LjLHubei contains Wuhan, but i only have data for the whole of Hubei03:54
chung%cases hubei03:55
Brainstormchung: In Hubei, China, there have been 68149 confirmed cases (0.1% of the population) and 4512 deaths (6.6% of cases) as of 24 days ago. Fatality can be broadly expected to lie between 2.2% (assuming deaths/cases with ⅔ undetected) and less than 6.5% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Hubei for time series data.03:55
chungLjL, your suggestion is very helpful, thanks a lot.03:55
gigasu_shidais lombardia still the hardest hit metro region in the world?03:55
LjLchung, you're welcome. i'll try to provide daily new cases later.03:55
gigasu_shidaerr, province03:55
LjLgigasu_shida, no03:55
LjLregion03:55
LjLalso it's a pet peeve of mine but please please call it Lombardy unless you're speaking italian or spanish :P03:56
LjLit's called Lombardy in English!03:56
gigasu_shidaoh sorry lol03:56
LjLanyway in italy the divisions are like, regions: Lombardy, Latium, Tuscany, etc; provinces: Milan, Rome, Florence, etc03:56
LjLregions usually contain multiple provinces03:57
gigasu_shidaoh Milan is a province i see03:57
LjLexcept Val d'Aosta which is weird, and Trentino-Alto Adige-Südtirol-South Tyrol-all the other names you can decide to call it, which is also weird03:57
LjLgigasu_shida, yes, it is also a municipality though, and that's smaller than the province03:57
LjLas in, the municipality (city) of Milan is the capital of the province of Milan03:58
LjL(actually, the "province" is now called the "metropolitan city of Milan", they did that for a bunch of provinces, but nobody cares and we still call it a province really)03:58
LjLso, it used to be: Milan, Province of Milan, Lombardy, Italy03:58
LjLnow it is: Milan, Metropolitan City of Milan, Lombardy, Italy03:58
LjLyou know, just to make addresses easier to type :P03:59
LjLbut what we actually type on letters is "Milano (MI)", with MI being the province abbreviation03:59
LjLgigasu_shida, anyway no Lombardy's data are... not low, but not terribly high either, but some other regions are becoming worrisome, like Veneto and some others04:00
LjLi suspect maybe they have more of the "UK variant"04:00
LjLi do think the variant is more infectious (personal, not scientific or medical opinion)04:00
gigasu_shidaoh gosh04:00
gigasu_shidahadn't heard about Venete04:01
LjLooooh04:01
LjLit's all white outside!04:02
chung%cases rome04:02
Brainstormchung: Sorry, rome not found. Either there aren't cases, or it's under a different name.04:02
chung%cases milan04:02
Brainstormchung: Sorry, milan not found. Either there aren't cases, or it's under a different name.04:02
LjL%cases latium04:02
BrainstormLjL: Sorry, latium not found. Either there aren't cases, or it's under a different name.04:02
LjL%cases lazio04:02
BrainstormLjL: Sorry, lazio not found. Either there aren't cases, or it's under a different name.04:02
LjLuh04:02
LjLi thought i *had* those04:02
LjL%cases lombardia04:02
LjL%cases lombardy04:02
BrainstormLjL: In Lombardy, Italy, there have been 471489 confirmed cases (4.7% of the population) and 24818 deaths (5.3% of cases) as of 20 hours ago. 196302 tests were performed (240.2% positive). Fatality can be broadly expected to lie between 0.1% (assuming prevalence as in tests) and less than 6.0% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Lombardy for time series data.04:02
BrainstormLjL: In Lombardy, Italy, there have been 471489 confirmed cases (4.7% of the population) and 24818 deaths (5.3% of cases) as of 20 hours ago. 196302 tests were performed (240.2% positive). Fatality can be broadly expected to lie between 0.1% (assuming prevalence as in tests) and less than 6.0% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Lombardy for time series data.04:02
LjLokay so what the hell does Covidly call Latium O.o04:02
chung%compare cn;us04:03
Brainstormchung: I need exactly two IPA phones!04:03
LjLchung, nope, that's not a command it has (well, it does, but for an unrelated thing). maybe CovBot does, i think?04:03
LjL!compare cn;us04:03
LjLsorry, i don't really know how to use CovBot :\04:03
jacklswthere is no comparison now04:04
chungYes CovBot does.04:04
jacklswxD04:04
LjLCovidly seems a bit random. Lombardy is called Lombardy, Tuscany is called Tuscany, etc, but Latium is called Lazio as in italian04:06
LjLand still, my bot doesn't get its data04:06
LjLBrainstorm, reload covid04:06
BrainstormLjL: <module 'covid' from '/home/brainstorm/brainstorm/bot/modules/covid.py'> (version: 2020-12-28 03:06:32)04:06
gigasu_shidaif Lombardy has about 10M people, then it's definitely harder hit so far than Los Angeles metro region04:06
LjL%cases latium04:06
BrainstormLjL: Sorry, latium not found. Either there aren't cases, or it's under a different name.04:06
LjLgigasu_shida, it does have about 10m04:06
BrainstormLjL: An error occurred while searching.04:06
gigasu_shidabut i have a feeling that could change next year04:06
BrainstormLjL: An error occurred while searching.04:06
LjL%cases lazio04:06
BrainstormLjL: In Lazio, Italy, there have been 156790 confirmed cases (2.7% of the population) and 3513 deaths (2.2% of cases) as of 20 hours ago. Fatality can be broadly expected to lie between 0.7% (assuming deaths/cases with ⅔ undetected) and less than 4.4% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Lazio for time series data.04:06
LjLalright04:06
LjLgigasu_shida, but they are probably not comparable population density-wise... Lombardy is pretty dense (heh), but it's not a whole metro area. it has three somewhat distinct metropolitan areas in it, more or less, but then also a fair amount of mountain and countryside. the metropolitan area of Milan is between 3 million and 6 million or so depending on who you ask04:08
LjL(the actual province is 3 million)04:08
LjL%wa population density of los angeles04:08
BrainstormLjL, Wolfram|Alpha (Los Angeles, California, United States | population density): Result: 3295 people per square kilometer → https://www.wolframalpha.com/input/?i=population+density+of+los+angeles04:08
LjL%wa population density of milan04:08
BrainstormLjL, Wolfram|Alpha (Milan, Lombardy, Italy | population density): Result: (data not available) → https://www.wolframalpha.com/input/?i=population+density+of+milan04:08
LjL%wa population density of lombardy04:08
BrainstormLjL, Wolfram|Alpha (Lombardy, Italy | population density): Result: 420 people per square kilometer → https://www.wolframalpha.com/input/?i=population+density+of+lombardy04:09
LjLyeah, a fair bit less04:09
gigasu_shidai can't think of a metro area hit harder than Milan tho04:09
gigasu_shidamaybe somewhere in Brazil04:10
gigasu_shidai'll have to research it04:10
LjLgigasu_shida, Milan was actually the *least* hit area within Lombardy, in the first wave. second wave was different, so i'm not sure on balance04:10
LjLbut Bergamo is also in Lombardy and definitely fared worse04:10
LjLMadrid was also in shambles in both the first and the second wave04:10
gigasu_shidaomg i didn't even hear about Bergamo04:10
chungLjL: What is %wa?04:11
LjLchung, wolfram alpha04:12
LjLgigasu_shida, https://www.arcgis.com/apps/opsdashboard/index.html#/4f74fc222b7041cd9cc3c52e62af1b8c ← have a look at these numbers... yes, Milan is first, but Brescia and Bergamo are both in Italy and *much* smaller than Milan, so comparatively, they were much harder hit04:12
LjLerr04:12
LjLalthough that's only updated to the first wave04:12
LjLthis is actually up to date for Lombardy https://lispa.maps.arcgis.com/apps/opsdashboard/index.html#/637ec3dc28ec4ea591cc5c724f12770104:13
chungLjL: I query private messages with Brainstorm, I only know 2 commands i.e. %modules and %commands, %wa is not mentioned.04:13
LjLchung, yes, i've done a bad job of documenting them, i'm sorry. many commands are about linguistics, also, since that's what the bot was initially created to do04:13
LjLthe commands relevant to COVID are %cases, %papers, %links and %vaccines04:14
LjL(it also accepts some variants of that)04:14
LjLand things like %wa are also generally useful... when they work, as Wolfram Alpha is quite temperamental with its timeouts04:14
euod[m]I realised the gpt2 neural network was made with pre-pandemic text sources, so it's blissfully unaware of covid19. 04:14
chung%papers04:15
Brainstormchung: Specify search terms with the syntax explained at https://preview.zbmed.de/04:15
LjL%papers long covid blood clots04:15
BrainstormLjL: An error occurred while searching.04:15
LjLi guess not04:15
LjL%papers blood clots04:15
BrainstormLjL, 7 papers: Cumulative effect of aging and SARS-CoV2 infection on poor prognosis in the elderly: Insights from transcriptomic analysis of lung and blood by Upasana Bhattacharyya et al, made available as preprint on 2020-06-16 at http://biorxiv.org/cgi/content/short/2020.06.15.151761 [... want %more?]04:15
LjLit gives you preprints04:15
chung%papers covid04:15
LjLchung, they are all about COVID, so that search keyword will probably crash the API a little :P04:16
LjLit will probably answer your command in a couple of minutes :D04:16
Brainstormchung, 19042 papers: Proposal of COVID-19 Clinical Risk Score for the management of suspected COVID-19 cases: a case control study by Sho Nakakubo et al, made available as preprint on 2020-07-14 at [u'https://doi.org/10.21203/rs.3.rs-42603/v1', u'https://www.researchsquare.com/article/rs-42603/v1.pdf'] [... want %more?]04:16
chungLjL: alright04:16
chunggreat!04:16
gigasu_shidaomg, some article said over half of ppl tested have antibodies in Bergamo04:17
gigasu_shidaand it was a supposedly random sampling of ppl04:17
LjLgigasu_shida, i think it was in some specific parts of the Bergamo provinces, but... you could be right04:17
LjLthere's definitely a very high prevalence there04:17
LjLbut also i'm always wary of antibody tests because some of them suck04:18
gigasu_shidaoh okay04:18
LjLwe do have a nationally run antibody survey and i wonder if they ever released *official* data, since i only saw interim data04:18
euod[m]it's basically useless false positive rate right?04:18
LjLeuod[m], it all depends on the test. some are probably okay04:21
LjLbut i'm pretty bummed at how ISTAT has only run that one national survey in May, and then no more04:21
LjLand they only have some preliminary data for it, in Italian only, meh04:22
LjLhttp://www.salute.gov.it/imgs/C_17_notizie_4998_0_file.pdf04:22
johnguyy[m]Flew into NY the other day and was greeted by a few military personnel asking for paperwork and a few ladies screaming about a “potential $10k fine if you didn’t sign them04:22
gigasu_shidawhat kind of paperwork?04:23
LjLi'm not going to fly anywhere if i can at all avoid it (which i probably can)04:23
gigasu_shidai was already scared of flying04:24
LjLi'm not so much scared of flying per se but i'm scared of the security checks, customs checks, check-in, and all of that stuff04:25
LjLonce i'm on the plane, it will... probably not crash, with overwhelming chances04:25
johnguyy[m]Paperwork- covid test, quarantine mandate, blah blah blah04:27
gigasu_shidai came across an article recently about how airplane cabins are pressurized. kinda freaked me out how some airplane personnel have fainted. the air system takes air directly from some part of the jet engine so in some cases some burned or unburned fuel can make its way into the cabin air at higher than acceptable concentrations04:27
johnguyy[m]Phone number/adress which I did not provide04:27
gigasu_shidaso now i have two things to be scared about ljl04:27
gigasu_shidaand yeah waiting in longs lines is annoying too04:27
danielp3344gigasu_shida: yeah 'bleed air' is supplied by the first stage or two of compressors from a jet engine04:28
danielp3344as they suck air in and compress it some is taken to perform various aircraft functions, the rest is mixed with fuel and burned04:28
gigasu_shidalooking back on my flight experiences i always thought the cabin air smelled faintly of jet fuel at times04:28
danielp3344lol04:29
johnguyy[m]It’s dirty air that’s for sure04:29
johnguyy[m]I always feel Particularly greasy after a flight04:29
gigasu_shidausually it was when we were still on the tarmac04:29
LjLgigasu_shida, a lot of freakish things can happen on an airplane. however, another data point you can look at is that even in people who are involved in things classified as *accidents*, the vast majority survives04:29
gigasu_shidait could have been just the bad air on the tarmac04:29
gigasu_shidaljl a lot of coverups happen when airplane personnel faint or what not, don't kid  yourself04:30
danielp3344johnguyy: if I'm gonna inhale unburned fuel and exhaust it had better be mine :P04:30
gigasu_shidahahhahahaha04:30
LjLi... don't think i'm "kidding myself". also where is the evidence of these coverups? or do you just assume they happen because there is no evidence?04:31
LjLsomething i would recommend is to *not* be sleeping during the takeoff and landing phases (including climb and approach)04:31
LjLbecause of two things04:31
LjL1) that's when (de)pressurization happens, and if your Eustachian tubes are clogged, during sleep you may not realize that you need to click them to unplug your ears, and at some point the pressure could damage the inner ear04:32
gigasu_shidai know ppl in the industry. stewardesses etc04:32
LjL2) that's also when the vast majority of accidents happen, so even though chances of an accidents are still very low, takeoff and landing are when you should be most aware of your surroundings, shoes on, and all that04:33
gigasu_shidayeah i have felt that pressure as well and forgot to squeeze the air against my squeezing my nose04:33
gigasu_shidaand my tubes are usually clogged it would seem04:33
LjLif you do that nose-squeezing thing, do it very gently04:33
LjLit may be enough to just plug your nose and only barely push any air, and click your ears04:34
gigasu_shidasorry that penultimate sentence was whack....i'm losing it. need coffee04:34
LjLyeah it kinda was :P but i understood you're probably talking about04:34
LjL%wik Valsalva maneuver04:34
LjL(at least one of its variants)04:34
BrainstormLjL, from English Wikipedia: The Valsalva maneuver is performed by moderately forceful attempted exhalation against a closed airway, usually done by closing one's mouth, pinching one's nose shut while expelling air out as if blowing up a balloon. Variations of the maneuver can be used either in medical examination as a test of [... want %more?] → https://en.wikipedia.org/wiki/Valsalva_maneuver04:34
LjLdone for this purpose https://en.wikipedia.org/wiki/Valsalva_maneuver#Normalizing_middle-ear_pressures04:35
LjL(but it's also done for other purposes)04:35
gigasu_shidait's an amazing maneuver04:39
gigasu_shidalike the heimlich maneuver04:39
gigasu_shidaand thank you i didn't know the name of it till now04:39
BrainstormNew from BBC Health: Covid-19: Hospitals face 'pressure' as coronavirus cases rise: Rising demand is down to the "rapid spread" of the new variant of Covid-19, health bosses say. → https://is.gd/y1sn4E04:57
BrainstormUpdates for Belgium: +847 cases (now 638877), +42 deaths (now 19200) since 22 hours ago05:53
BrainstormNew from The Indian Express: World: Europe rolls out ‘new weapon’ vaccines in bid to slay COVID → https://is.gd/pp0B4F06:12
BrainstormNew from r/WorldNews: worldnews: Zhang Zhan: China jails citizen journalist for Wuhan reports → https://is.gd/smAaQa06:37
BrainstormNew from The Indian Express: World: Trump signs pandemic aid and spending bill, averting government shutdown → https://is.gd/2yHKfj07:02
BrainstormUpdates for Texas, United States: +22848 cases (now 1.7 million), +50 deaths (now 26966) since 23 hours ago — South Carolina, United States: +7287 cases (now 296179), +31 deaths (now 5155) since 23 hours ago — Quebec, Canada: +6793 cases (now 192665), +110 deaths (now 8023) since 2 days ago — Minnesota, United States: +2516 cases (now 409061), +40 deaths (now 5206) since 23 hours ago07:13
DocScrutinizer05>>no, jackass, when you got your vac shot doesn't mean you get special privileges now and may drop the habit to wear a mask and keep distance. You already got the privilege to get vaccinated, now the only special privilege you got is to STFU and behave until everybody got their shot<<07:41
BrainstormNew from r/WorldNews: worldnews: China jails citizen journalists for Wuhan reports → https://is.gd/H1tJpo07:52
BrainstormNew from Medical Xpress: US surpasses 19 mn Covid-19 cases: Johns Hopkins: The United States surpassed 19 million coronavirus cases Sunday, figures from Johns Hopkins University showed, adding one million new cases in less than a week. → https://is.gd/tAjmEz08:05
BrainstormNew from The Indian Express: World: China jails citizen-journalist for four years over Wuhan virus reporting → https://is.gd/qrOyxW08:17
BrainstormNew from BBC Health: Covid-19: Hospitals face 'pressure' as coronavirus cases rise: Rising demand is down to the "rapid spread" of the new variant of Covid-19, health bosses say. → https://is.gd/y1sn4E08:54
BrainstormNew from Science-Based Medicine: 2020 and the pandemic: A year of physicians behaving badly: Looking back on 2020, if there's one thing that the COVID-19 pandemic has taught us, it's that crises reveal character. Unfortunately, the character of too many physicians has been found wanting, as they spent 2020 denying the pandemic, peddling quack cures, or [... want %more?] → https://is.gd/haCTlo09:06
BrainstormNew from The Indian Express: World: Italy turns to flower power to help spread vaccine message → https://is.gd/mm4Jc409:44
BrainstormNew from The Indian Express (Health): Health: Wondering what the new coronavirus strain is all about? A doctor explains → https://is.gd/q6PmXO09:56
BrainstormNew from Reddit (test): CoronaVirus_ITALIA: Il presidente De Luca si fa vaccinare ma non è in lista: le dosi erano solo per medici e infermieri → https://is.gd/iJpciw10:08
BrainstormNew from Medical Xpress: China ramps up virus controls to head off winter wave: Temperature checks, queues for tests and inspections at airports—Chinese authorities have stepped up health checks to snuff out the threat of a coronavirus resurgence. → https://is.gd/sVvciP10:21
BrainstormNew from BBC Health: Covid-19: Hospitals under pressure as coronavirus cases rise: Rising demand is down to the "rapid spread" of the new variant of Covid-19, health bosses say. → https://is.gd/y1sn4E10:34
de-factoRKI COVID-19 Germany 2020-12-28 (btween years rep:): Weekly Incidence 157.7/100k, Infections +10976 (1651834 total), Fatalities +348 (30126 total), COVID@ICU 5604 (incl 3011 on ventilator)10:44
BrainstormNew from Reddit (test): nCoV: Zhang Zhan: China jails citizen journalist for Wuhan reports | 28DEC20 → https://is.gd/10FrAl10:46
Arsaneritnot sure if the phrase "between years" exists in English10:58
BrainstormNew from Reddit (test): CoronaVirus_ITALIA: No, l’Italia non ha meno vaccini rispetto agli altri Paesi UE → https://is.gd/NoHipQ10:58
DocScrutinizer05de-facto: my chart already shows a new edge for yesterday. We'll see how long it takes until numbers for 24. ff stabilize on reasonable non-bogus values11:11
BrainstormNew from BBC Health: Covid-19: Hospitals under pressure as coronavirus cases rise: Rising demand is down to the "rapid spread" of the new variant of Covid-19, health bosses say. → https://is.gd/y1sn4E11:11
DocScrutinizer05https://i.imgur.com/z1YRZQJ.png https://i.imgur.com/7l24OUl.png https://i.imgur.com/e8We3Ar.png11:22
BrainstormNew from ProPublica: After a Violent Crime, Arizona Promised Reforms for People With Developmental Disabilities. It Has Yet to Deliver.: by Amy Silverman for Arizona Daily Star ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. This article was produced in [... want %more?] → https://is.gd/WqHxKd11:24
DocScrutinizer05%why11:25
BrainstormWe are unable to find any reasons *why* this should work.11:26
BrainstormNew from r/WorldNews: worldnews: South Korea reports cases of COVID variant - and says they came from UK → https://is.gd/AKcs2f11:49
BrainstormNew from BBC Health: Covid-19: Hospitals under pressure as coronavirus cases rise: Rising demand is down to the "rapid spread" of the new variant of Covid-19, health bosses say. → https://is.gd/y1sn4E12:13
mobidropis there really a new variant or is this just their failure to manage spread?12:15
de-factomobidrop, https://en.wikipedia.org/wiki/Variant_of_Concern_202012/0112:37
de-factothats the UK variant12:37
de-factoSA variant https://en.wikipedia.org/wiki/501.V2_variant12:38
de-factofor updates on newest info look at "Dr Emma Hodcroft" twitter at https://twitter.com/firefoxx6612:39
de-factohttps://virological.org/t/preliminary-genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-the-uk-defined-by-a-novel-set-of-spike-mutations/56312:41
de-factohttps://www.krisp.org.za/publications.php?pubid=31512:48
de-factohttps://www.medrxiv.org/content/10.1101/2020.12.21.20248640v112:48
de-factohttps://www.ecdc.europa.eu/en/publications-data/threat-assessment-brief-rapid-increase-sars-cov-2-variant-united-kingdom12:49
de-factohttps://www.who.int/publications/m/item/statement-of-the-who-working-group-on-covid-19-animal-models-(who-com)-about-the-uk-and-south-african-sars-cov-2-new-variants12:51
de-factomobidrop, ^^ and lots of more info12:52
generaso basically sis is nCoV-dezember-202013:02
de-factoone of the mutations of those that might be of importance is on the S-protein at position 50113:08
de-factoN501Y (3876 sequences): 3116 England, 478 Wales, 202 South Africa, 37 Australia/VIC, 18 Scotland, 10 Denmark, 5 USA/MA, 2 Netherlands, 2 Australia/NSW, 1 USA/OR, 1 Italy, 1 USA/NY, 1 Gibraltar, 1 Brazil, 1 USA/IL13:08
de-factobut thats not representative because it depends on how may sequences a country collects13:09
de-factoe.g. UK collects 100x more than most other EU contries13:09
BrainstormNew from The Indian Express (Health): Life-style: How WFH in pandemic changed our home decor, furniture → https://is.gd/4mUM9z13:28
BrainstormNew from r/WorldNews: worldnews: Piecemeal data releases threaten to undermine Sinovac's COVID-19 vaccine → https://is.gd/uF1ZiM14:30
BrainstormNew from BBC Health: Covid-19: Hospitals under pressure as coronavirus cases rise: Rising demand is down to the "rapid spread" of the new variant of Covid-19, health bosses say. → https://is.gd/y1sn4E14:43
BrainstormUpdates for Germany: +10833 cases (now 1.7 million) since 23 hours ago14:53
BrainstormUpdates for Lesotho: +231 cases (now 2956) since 5 days ago — Switzerland: +10087 cases (now 438284), +74 deaths (now 7283) since 21 hours ago15:11
BrainstormNew from Emma Hodcroft: @firefoxx66: Many are interested in using the 69/70 deletion to scan for cases of the new #SARSCoV2 variants.As it can impact some primers (seen as an 'S drop-out' in PCR), it can be a high-throughput way to check for the 'SE England' variant - but some important things to remember!1/5 → https://is.gd/RspWfc15:21
BrainstormNew from Medical Xpress: More work needed to identify risk from Nigeria strain, says researcher: A researcher who identified a novel coronavirus variant in Nigeria has cautioned against automatic assumptions that it poses similar risks to strains that have emerged elsewhere. → https://is.gd/YFwyI115:34
CoronaBot04/r/covid19: SARS-CoV-2-specific T cell memory is long-lasting in the majority of convalsecent COVID-19 individuals (84 votes) | https://www.biorxiv.org/content/10.1101/2020.11.15.383463v1.full | https://redd.it/klpvp715:47
BrainstormNew from Emma Hodcroft: @AdamJKucharski: RT by @firefoxx66: Why a SARS-CoV-2 variant that's 50% more transmissible would in general be a much bigger problem than a variant that's 50% more deadly. A short thread... 1/ → https://is.gd/dnJ7uG16:12
BrainstormUpdates for Liechtenstein: +20 cases (now 2038), +4 deaths (now 35) since 21 hours ago16:13
BrainstormUpdates for Netherlands: +7976 cases (now 771603), +39 deaths (now 11058) since 16 hours ago16:32
BrainstormNew from r/WorldNews: worldnews: 19 SARS-CoV-2 mutations in India can evade antibodies, 1 causes reinfection → https://is.gd/FgbmBm16:50
BrainstormNew from Scientific American: Debunking the False Claim That COVID Death Counts Are Inflated: President Trump and other conspiracy fantasists touted the fake claim that COVID death counts are exaggerated. But three kinds of evidence point to more than 250,000 deaths -- Read more on ScientificAmerican.com → https://is.gd/SIZ5Zm17:16
Jigsy%cases UK17:25
BrainstormJigsy: In United Kingdom, there have been 2.3 million confirmed cases (3.4% of the population) and 70806 deaths (3.1% of cases) as of 10 hours ago. 52.3 million tests were performed (4.4% positive). See https://offloop.net/covid19/?default=United%20Kingdom for time series data.17:25
JigsyUK now has 40K/day.17:25
JigsyAnd they're opening schools next week.17:25
JigsyThis should be a fun trainwreck to watch.17:26
BrainstormUpdates for United Kingdom: +35421 cases (now 2.3 million), +350 deaths (now 70907) since 22 hours ago17:28
BrainstormNew from BBC Health: Covid-19: Hospitals under pressure as coronavirus cases rise: Rising demand is down to the "rapid spread" of the new variant of Covid-19, health bosses say. → https://is.gd/y1sn4E17:28
Arsaneritwhy fun?17:29
JigsyBecause the UK are still doing such a shit job of managing this situation17:30
Jigsy+ .17:30
JigsyA year later.17:30
JigsyIt's like this.17:30
Jigsy"We'll be doing this."17:30
Jigsy*COVID CASES SPIKE 1000%*17:30
Jigsysurprised_pikachu.jpg17:30
JigsyEvery time.17:31
Arsaneritis that fun?17:33
Arsaneritpeople are suffering and dying, livelihoods are damaged and destroyed, I don't really find it fun personally17:34
JigsyI'm thinking more of a government angle, not a people angle.17:35
JigsyThough the people aren't exactly helping this situation either...17:35
Arsaneritsome are, some aren't17:35
JigsyYou'd be amazed how many people I see not wearing masks.17:36
JigsyAnd the only time they put them on is in the store.17:36
JigsyI walk past people outside and they're not wearing shit.17:36
Arsaneritis there a general outdoor mask requirement where you are?17:37
JigsyI don't believe so.17:38
JigsyBut they're walking past other people...17:38
JigsyHow is this not common sense?17:38
ArsaneritI don't wear a mask when walking in the forest, but I do keep ≥1.5 metre distance.17:38
ArsaneritI don't know.  I'm confused.  The Robert Koch Institut defines a class I contact person as having been less than 1.5 metre distant for 15 minutes.  Does that mean that when I just quickly walk by someone outside that there is a negligible risk of transmission (when not outright coughing in their face)?17:39
ArsaneritThat's the criteria for the Corona Warn App, at least the way it's configured/programmed in Germany.17:39
de-factoimho masks should be worn without exceptions in any place (also outdoors) where there is the chance the people might not keep at least 2m distance to each others, even short times, noone sneezes, coughs or talks with the purpose to infect others, yet it happens17:49
de-factoyet when i would go for a walk alone in the forest or on the fields i would not wear a mask because then its several hundred meters at least till next human contact, but i always would put it on as soon as i expect to come into a situation with less distance even if its only a few seconds17:50
de-factosimply because its not only my own personal risk but also the risk of all of society and economy17:51
BrainstormNew from EMA: What's new: General: COVID-19 vaccines: key facts → https://is.gd/ssCPcx17:54
BrainstormUpdates for Canada: +8546 cases (now 553112), +136 deaths (now 14970) since 23 hours ago18:05
BrainstormNew from In The Pipeline: Holiday Recipe: Banana Bread: We just finished off a loaf of this not long ago around here; it’s a recipe that my wife makes when we have overripe bananas (and since we have both our college-aged kids at home for now, it goes pretty quickly). Like most such recipes, it comes together quickly. You’ll need shortening [... want %more?] → https://is.gd/mg6k1I18:07
IndoAnon9,99> Elsewhere in Germany, in the Vorpommern-Ruegen district, authorities said eight workers in an elderly care home in Stralsund city received five times the recommended dose of the BioNTech/Pfizer vaccine on Sunday.18:17
de-factoOMG did they inject them a whole ampule?18:20
BrainstormNew from Medical Xpress: German care home workers given five times vaccine dose: Eight care home workers in Germany were accidentally injected with five doses of the COVID-19 vaccine, local authorities said Monday—but are suffering no serious ill effects so far. → https://is.gd/pLdH1D18:20
de-factoin each vile there are 5 doses of 30 µg18:20
generathats what modeRNA needs anyway, no?18:24
de-factoits not like they would have any problems selling, its more like they cant produce enough of the doses18:30
IndoAnonIt's more like these clowns can't read the instruction18:32
IndoAnon99,11https://www.reuters.com/article/reutersComService_2_MOLT/idUSKBN29214Q18:33
de-factoplease strip the colors18:34
de-factohttps://www.deutsche-apotheker-zeitung.de/_Resources/Persistent/8/3/e/d/83ed6a12587eb295d25f04e980c80dec0717b737/226386603-5400x3036-637x358.jpg18:34
IndoAnonlel18:34
de-factohttps://www.pharmazeutische-zeitung.de/fileadmin/_processed_/2/6/csm_69084_5891f2e145.jpg18:35
IndoAnonCan't they use samething like epipen, seriously18:35
de-facto"After dilution, vial contains 5 doses of 0.3ml"18:35
de-factohmm what could that mean? "5 doses"? Anyone any ideas?18:36
de-factohttps://www.deutsche-apotheker-zeitung.de/_Resources/Persistent/d/d/2/c/dd2c06dde275ce9f20a8646b2145f99a2512747a/imago0108699619h-3000x1688-637x358.jpg18:37
IndoAnonThey probably need to withdraw the 0.3ml equivalent before being tittered18:37
de-factohttps://www.nytimes.com/interactive/2020/health/pfizer-biontech-covid-19-vaccine.html18:38
de-factohttps://static01.nyt.com/newsgraphics/2020/12/05/how-coronavirus-vaccines-work/assets/images/201208-pfizer-vial-600.jpg18:38
IndoAnonWell, 0.3ml after meant it's equivalent to ~6 droplets. That's really smol quantity18:38
de-factoso what? use a small syringe, i am sure it was possible to know that in advance and order the correct equipment18:39
de-factohttps://www.aerztezeitung.de/Bilder/Der-Corona-Impfstoff-von-BioNTechPfizer-soll-noch-in-dieser-192483h.jpg18:40
IndoAnonThe fact that the mishaps happened meant they're not using the correct wordings, as most vial is supposed to be single use.18:41
IndoAnon*vaccine vial usually is single use only18:42
de-factohttps://www.deutsche-apotheker-zeitung.de/_Resources/Persistent/8/f/e/d/8fed2ebb3eb95af0cce5f033166c65d84f7f50f2/Biontech%20Quelle%20%20ZUMA%20Press%20imago0108454452h_DAZ-637x359.jpg18:42
IndoAnonA big warning label could've prevented this18:42
de-facto"WARNING, keep away from idiots"?18:42
IndoAnon More like >this is 5 doses, moron18:43
de-factolike seriously its written there "5 doses" in German "5 Dosen"18:43
IndoAnonFunny, because dosen in indonesian is lecturer18:44
IndoAnonLoL18:44
de-factoanyhow is anything known about how they tolerated this experiment of getting 150µg modRNA?18:44
BrainstormNew from Medical Xpress: Phase 3 trial of Novavax investigational COVID-19 vaccine opens: The Phase 3 trial of another investigational coronavirus disease 2019 (COVID-19) vaccine has begun enrolling adult volunteers. The randomized, placebo-controlled trial will enroll approximately 30,000 people at approximately 115 sites in the United States and [... want %more?] → https://is.gd/IFp71918:44
IndoAnonDunno, because we skipped so many procedure18:46
IndoAnonI hope governments order them to fulfill the necessary research that was cut short18:47
IndoAnonIf they still want to kept the immunity from being sued18:48
de-factoDid you read anything about the Moderna mRNA-1273 vaccine having a full RNA sequence available?18:49
de-factoi am still searching for it18:49
de-factoi only found the two sequences for the German vaccines18:50
de-factohttps://www.who.int/medicines/publications/druginformation/issues/WHO_DI_34-3_PL124-SpecialEdition.pdf18:51
de-facto bnt162b2: tozinameran, Spike (modRNA) https://mednet-communities.net/inn/db/media/docs/11889.doc18:51
de-factozorecimeran: CureVac, RBD (no 1mΨ) https://mednet-communities.net/inn/db/media/docs/11868.doc18:51
de-factoboth seem to contain the mutations K986P and V987P to stabilize the spike glycoprotein in prefusion configuration18:52
de-factoid guess Moderna uses the same sequence but id like to see their data too18:53
IndoAnonWell, i missed that... I went to ikea on christmast and still fatigued18:54
BrainstormUpdates for Italy: +8581 cases (now 2.1 million), +445 deaths (now 72370) since 23 hours ago18:54
IndoAnonI think I saw that conversation on the thread too.  Let me search a bit18:55
de-factoafaik both BioNTech and Moderna use modRNA hence with 1-methyl-3'-pseudouridylyl (m1Ψ) instead of uridine (U) https://en.wikipedia.org/wiki/Nucleoside-modified_messenger_RNA18:57
de-factoCureVac uses conventional mRNA18:57
de-facto.title https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449617/18:58
Brainstormde-facto: From www.ncbi.nlm.nih.gov: N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density18:58
IndoAnonhmm, nope19:00
IndoAnonNot much of discussion19:00
IndoAnonhttps://www.fda.gov/media/144245/download19:03
IndoAnon>Among non-serious unsolicited adverse events, there was a numerical imbalance of four cases of Bell’s palsy in the vaccine group compared with no cases in the placebo group, though the four cases in the vaccine group do not represent a frequency above that expected in the general population.19:03
IndoAnon>Otherwise, there were no notable patterns or numerical imbalances between treatment groups for specific categories of non-serious adverse events (including other neurologic, neuroinflammatory, and thrombotic events) that would suggest a causal relationship to BNT162b2 vaccine19:03
de-factodo they provide an modRNA sequence anywhere for  mRNA-1273?19:05
de-factoi wonder how their polyA tail looks like in comparison to BNT162b219:06
de-factobecause mRNA1273 is a 100µg dose vs BNT162b2 is 30µg modRNA per dose19:06
de-factoCureVac even only 12µg19:07
IndoAnonhmm19:07
IndoAnonnope, I don't see the discussion regading the modRNA19:08
IndoAnonspecifically for the mRNA-127319:09
de-factoits going to come, its on twitter already19:09
de-factolike discussion about the sequences19:09
BrainstormNew from Medical Xpress: Model used to evaluate lockdowns was flawed: In a recent study, researchers from Imperial College London developed a model to assess the effect of different measures used to curb the spread of the coronavirus. However, the model had fundamental shortcomings and cannot be used to draw the published conclusions, claim Swedish [... want %more?] → https://is.gd/W97KIY19:09
de-factobut yeah i havent found data for Moderna mRNA-1273 yet19:09
IndoAnonhttp://web.archive.org/web/20200917125542/https://www.modernatx.com/sites/default/files/mRNA-1273-P301-Protocol.pdf19:10
IndoAnonThat's all i got19:10
de-factoyeah thats the clinical protocol for the study19:11
IndoAnonhttps://archive.4plebs.org/pol/thread/289634862/#289665704 > all it is as far as I can tell is a strand of RNA that encodes a covid spike protein with a methylated cap and a poly-A tail to ensure translation and half life in cells. this provokes an immune response so when live virus is introduced it provokes the same response and prevents productive infection19:13
IndoAnonSeems fellow anon is aware of this19:14
IndoAnon>So, why has everybody seemingly gotten memoryholed of the 33 poly-A-tail of this virus in the early genomes that's seemingly disappeared or changed, but why? 19:15
de-factoyeah except probably not only the cap is methylated but rather all uridine replaces with 1-methyl-3'-pseudouridylyl (i guess, i dont have that info about Moderna)19:16
de-factoafaik that poly-A tail may get shorter with each transcription hence they want to make it as long and durable (with some intermediate sequences allowing over 100 A's) as possible19:17
de-factosame idea about the modRNA make its biological half life in a cell longer, because it will get destroyed pretty quickly anyhow19:18
IndoAnonyea19:23
IndoAnonIt makes my mate wonder abaut tha19:24
ArsaneritAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA?19:25
Arsanerithttps://bioinformatics.stackexchange.com/q/1122719:26
IndoAnonLOL19:26
Arsanerit(why) can't vaccines designed such that vaccinated people "infect" other vaccinated people, just like the virus does?  It would make things faster?19:27
IndoAnondo you know about the borg?19:30
Arsaneritno19:30
CoronaBot04/r/coronavirus: People with coronavirus are still getting on planes. No one knows how many. (10558 votes) | https://www.washingtonpost.com/travel/2020/12/28/passenger-covid-flight-airlines-positive/ | https://redd.it/klrnsx19:31
ubLIX[m]"We have infected a pool of people with a highly transmissible sterilising 'vaccine' that will now spread throughout the population."19:32
ubLIX[m]yup, this will go down extremely well with the anti-vax crowd :p19:32
BrainstormNew from NPR: 'I Regret Nothing': Doctor Who Criticized Trump Parade Works Last Day At Walter Reed: "I stand by my words," says Dr. James Phillips, the Walter Reed physician who said the president's decision to drive by supporters while being treated for COVID-19 endangered his security detail. → https://is.gd/srg3di19:34
IndoAnonlel19:34
ArsaneritubLIX[m]: maybe they will finally adopt distancing? :)19:35
ubLIX[m]haha. as if by magic, they streets would be empty19:36
BrainstormUpdates for France: +236 deaths (now 62907) since 22 hours ago19:38
IndoAnonaaaaaaaaaaa19:38
IndoAnon>Is it possible to project/calculate the probable vacc efficacy based on the mRNA sequence they harbor, when you also have the sequences of the currently circulating strains' spike proteins with their mutations?19:40
IndoAnonDamn, moar question de-facto 19:40
BrainstormNew from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 24 dicembre 2020: Ulteriori misure  urgenti  in  materia  di  contenimento  e  gestionedell'emergenza epidemiologica da COVID-19. (20A07237) → https://is.gd/fc3IU819:47
de-factowell when both RNA sequences are known (e.g. vaccine and mutant wild type) then also the S-protein structure is known for both, so good luck calculating the binding of antibodies to that...19:52
de-factoif the antibodies are known that is19:53
BrainstormNew from Medical Xpress: SARS-CoV-2 infection rate low in patients receiving antitumor therapy: (HealthDay)—The rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is 0.68 percent among patients receiving antitumor treatment, according to a research letter published online Dec. 17 in JAMA Oncology. → https://is.gd/PWYqbt19:59
rmonten[m]So what are we thinking about the strategy to give everyone the first dose of a 2-dose vaccine first, before going back through the population for the 2nd dose? Do we expect a longer term interval between the 2 doses to be better/worse (dangerous?) in comparison to a 21 day interval?20:08
BrainstormNew from BBC Health: Covid-19: Concern at 'unprecedented' infection level in England: Covid cases rise in the UK as the number of people in England's hospitals goes above the first peak. → https://is.gd/y1sn4E20:12
BrainstormUpdates for Spain: +23796 cases (now 1.9 million), +298 deaths (now 50122) since 4 days ago20:15
BrainstormUpdates for Netherlands: +7978 cases (now 771605) since 20 hours ago20:59
BrainstormNew from Lockdowns from Wikipedia: 36.76.233.37: /* Indonesia */Indonesia still no lockdown within their territoriea: Indonesia: Indonesia still no lockdown within their territoriea ← Previous revision Revision as of 20:14, 28 December 2020 Line 105: Line 105: LSSR measures were lifted throughout the month of May despite continued community [... want %more?] → https://is.gd/uhc8nH21:26
BrainstormNew from BBC Health: Covid-19: Concern at 'unprecedented' infection level in England: Covid cases rise in the UK as the number of people in England's hospitals goes above the first peak. → https://is.gd/y1sn4E22:04
BrainstormUpdates for Eswatini: +203 cases (now 8687), +2 deaths (now 167) since 23 hours ago22:13
BrainstormUpdates for France: +363 deaths (now 63109) since 21 hours ago23:09
BrainstormNew from r/WorldNews: worldnews: Australia insists WHO inquiry into Covid origin must be robust, despite China tensions → https://is.gd/tePd9y23:31
CoronaBot04/r/covid19: Novavax Announces Initiation of PREVENT-19 Pivotal Phase 3 Efficacy Trial of COVID-19 Vaccine in the United States and Mexico (81 votes) | https://ir.novavax.com/news-releases/news-release-details/novavax-announces-initiation-prevent-19-pivotal-phase-3-efficacy | https://redd.it/klrydb23:32
CoronaBot04/r/covid19: Vitamin D deficiency correlates with a reduced number of natural killer cells in intensive care unit (ICU) and non-ICU patients with COVID-19 pneumonia (80 votes) | https://www.sciencedirect.com/science/article/pii/S1109966620302840 | https://redd.it/klxnjm23:38
BrainstormNew from FDA Press Releases: FDA: Coronavirus (COVID-19) Update: December 28, 2020 → https://is.gd/CE7MD623:57

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