libera/##covid-19/ Tuesday, 2021-01-12

gigas_cedarhttps://www.france24.com/en/live-news/20210111-argentine-judge-orders-unproven-treatment-for-covid-patient00:05
gigas_cedarwhat the hell?!?!00:05
BrainstormNew from Medical Xpress: COVID-19, cold, allergies and the flu: What are the differences?: If you have signs or symptoms of coronavirus disease 2019 (COVID-19), it's important that you contact your health care provider right away for medical advice. But COVID-19, the common cold, seasonal allergies and the flu (influenza) cause many similar symptoms. → https://is.gd/phHAi000:07
jhgjh62hi, new here. so, is this the chat for believers or non-believers? ;))00:09
jameshandcockandIt's for people who know the science 00:18
jameshandcockandThere's nothing to not believe 00:18
jameshandcockandIf you don't "believe" in covid, you're a dumbass 00:18
BrainstormUpdates for France: +310 deaths (now 68060) since 22 hours ago — Switzerland: +40 deaths (now 8364) since 9 hours ago00:31
BrainstormNew from Medical Xpress: Concerning drop in the number of people with mental health problems seeking help revealed: During April 2020, while the UK was in full lockdown, there was a drop of more than a third in the number of people seeking help for mental illness or self-harm according to research involving 14 million people registered at general [... want %more?] → https://is.gd/i0MDuu00:43
CoronaBot04/r/covid19: On a new variant of SARS-CoV-2 found in people returning from Brazil (80 votes) | https://www.niid.go.jp/niid/ja/diseases/ka/corona-virus/2019-ncov/10107-covid19-33.html | https://redd.it/kuis8900:51
DocScrutinizer05moin! what's new?00:53
BrainstormUpdates for Germany: +11751 cases (now 1.9 million), +663 deaths (now 42097) since 22 hours ago — Canada: +6943 cases (now 668401), +137 deaths (now 17086) since 23 hours ago01:40
BrainstormNew from BBC Health: Covid: Eyesight risk warning from lockdown screen time: More than a third of people using screens more during lockdown reported eyesight changes, a study suggests. → https://is.gd/CEzAs201:43
LjLDocScrutinizer05, servus01:45
BrainstormNew from Medical Xpress: Six months later, most Wuhan COVID survivors still have health issues: (HealthDay)—Concerns about "long-haul" symptoms in COVID-19 survivors may be reignited by a new study: It finds that 3 out of 4 patients from Wuhan, China—where the pandemic originated—were still suffering at least one lingering health problem six [... want %more?] → https://is.gd/n0yyCg01:56
LjLugh02:03
LjLugh also at the fact even a medicine-specific paper like Medical Xpress doesn't actually link to the studies involved02:06
BrainstormNew from https://covid19.specops.network : Add NYMag article about lab-leak hypothesis: I think it's really not all that implausible, and the article cites a lot of opinions both for and against this hypothesis, so I think it's fine to include it → https://is.gd/BYh1As02:28
de-factoChiao LjL already read the newest Derek Lowe?02:37
LjLde-facto, if it's the one about mRNA, yes02:38
de-facto.title https://blogs.sciencemag.org/pipeline/archives/2021/01/11/rna-vaccines-and-their-lipids02:38
Brainstormde-facto: From blogs.sciencemag.org: RNA Vaccines And Their Lipids | In the Pipeline02:38
LjLyes02:38
LjLde-facto, have you seen the two italian studies i posted? more, okay let's keep calling it tentative, evidence it was in lombardy in november/december02:38
de-factoquite a neat read, he even links Bert02:39
de-factoyou mean the wiley and cdc?02:40
LjLde-facto, yes02:46
de-factoSo the cdc claims to have found a fragment of 409 bp identical to the Wuhan-HU-1NC_045512.2 reference sequence02:48
LjLde-facto, if by "the CDC" you mean "a bunch of Italian researchers writing a letter to the CDC"02:48
de-factohttps://www.ncbi.nlm.nih.gov/nuccore/MW30395702:49
de-factoyes sorry for my inaccurate referencing it02:49
LjLabout as short as the other sequences we have from the sewers02:50
de-facto.title https://wwwnc.cdc.gov/eid/article/27/2/20-4632_article02:50
Brainstormde-facto: From wwwnc.cdc.gov: Early Release - Evidence of SARS-CoV-2 RNA in an Oropharyngeal Swab Specimen, Milan, Italy, Early December 2019 - Volume 27, Number 2—February 2021 - Emerging Infectious Diseases journal - CDC02:50
de-facto"collected from a 4-year-old boy who lived in the surrounding area of Milan and had no reported travel history. On November 21, the child had cough and rhinitis; about a week later (November 30), he was taken to the emergency department with respiratory symptoms and vomiting. On December 1, he had onset of a measles-like rash; on December 5 (14 days after symptom onset), the oropharyngeal swab specimen was obtained for clinical diagnosis of 02:51
de-factosuspected measles."02:51
LjLde-facto, the fact he had no travel history is not surprising if we also consider the other paper where the infection would be placed onto a November timeline02:52
LjLso presumably it was already widely circulating by December02:52
LjLobviously not widely enough to notice at scale, but widely enough to cause a bunch of strange/suspicious medical cases02:52
LjL(which i will reiterate once more, was something i heard already in early spring, in particular that italian doctors had identified a few cases of pneumonia that were not typical and they couldn't explain)02:53
BrainstormUpdates for Botswana: +11 deaths (now 59) since 3 days ago02:54
de-factoyeah thats what i wonder, if it would have been widely circulating (beyond few clusters) it would have to be expected to develop the dynamics we now are painfully aware about02:55
LjLde-facto, you always say that, but i always say... it did. eventually. it didn't do it immediately, but, after the lockdown, it didn't spike back up immediately after in italy, it took a couple of *months* at least to start rising again02:55
LjLso we have direct evidence that even without lockdowns in place, at first, this thing doesn't just explode, but grows a bit more subtly02:56
LjLi don't know why, if maths alone explain it, or it's somehow a characteristic of this virus02:56
LjLbut we've seen it happen, so i don't see why it wouldn't have happened in nov/dec 201902:56
de-factoblast finds those for that sequence https://blast.ncbi.nlm.nih.gov/Blast.cgi?CMD=Get&RID=ZU084FC501302:56
LjLlooks like a lot of sequences from a lot of places02:57
LjLit's probably not specific enough to give us any tree hints02:57
de-factoin an unaware naive population it would tend to spread in clusters rather than what we observe now in a painfully aware partly naive (in an immunologic sense) population02:58
de-factohence have a much higher R ~ R0 ~3 or such compared to what we see now02:58
de-factobecause of the full extend of overdispersion kicking in (few carriers causing many cases)02:59
de-facto"However, earlier strains also might have been occasionally imported to Italy and other countries in Europe during this period, manifesting with sporadic cases or small self-limiting clusters."03:02
BrainstormNew from r/WorldNews: worldnews: Moderna’s COVID-19 vaccine expected to provide immunity for up to 1 year → https://is.gd/pvseSg03:05
LjLpft, Pfizer does two!03:07
LjL(as if anyone really knows)03:07
LjLSORRY I MENA BIONTECH03:07
de-factoexponentially more depending on where you place the threshold :D03:09
de-factoim not sure if i read the blast correctly but it looks like its in the middle of the S-protein03:10
de-factoso that means those 409 bp are definitely from SARS-CoV-203:12
de-facto(not that i doubted it, just wanted to know which part of it they found there)03:12
LjLde-facto, indeed keep in mind that we are generally dealing with D614G but if this is more like the original wuhan strain, then it likely wouldn't be as infectious03:14
LjLalso i'm not set to prove that it originated in italy or anything03:14
LjLsince i think it's possible it was originally going unnoticed for a while, it could still have originated around wuhan while it was also being exported to lombardy03:15
BrainstormNew from The Indian Express: World: UN: COVID-19 herd immunity unlikely in 2021 despite vaccines → https://is.gd/9OXrJA03:17
de-factoyeah D614G is more infections but not *that* crazy much more id assume, so still the Wuhan alike variant was already capable to cause serious outbreaks03:19
LjLi wouldn't assume that. i think D614G made a big difference in how China vs "the world" managed the outbreak03:20
LjLnot saying it was the only factor, but a big one03:20
de-factoi see no reason to assume a widespread circulation, id rather go with the fewest causes as possible hence a few little clusters of which that boy may have been member already could explain that03:21
de-factowell except for the sewer samples but PCR got a crazy high amplification, what was their CT value for that one again?03:26
de-factoso assuming all that is correct, what implications does it have? it circulated much earlier than we expected? well ok and undercover? we kinda know that already03:29
LjLuh now we knew that already?03:31
LjLi've been trying to make that point for months03:31
de-factoand those sequence parts dont really give us new insights in its phylogenetic tree, would have been fascinating to see "pre Wuhan" variant circulating, yet it looks like03:31
LjLand it was always tinwhiskers being like "even though there's evidence it's easier to assume the evidence is flawed"03:31
LjLnow we know that already?03:31
BrainstormUpdates for Netherlands: +2717 cases (now 881689), +25 deaths (now 12436) since 19 hours ago03:31
de-factoi mean we knew already that significant portion of the spread is asymptomatic and in clusters03:31
de-factoim not saying anything is flawed03:33
de-factojust the minimal assumptions to explain those findings (minimal in terms of implications of other side effects than the ones detected)03:35
de-factoand then asking what we can learn for those03:35
de-factofor example it would be neat to have a full sequence with some mutations distinguishing it from Wuhan reference sequence, yet its difficult (impossible?) with degraded samples containing low concentrations03:40
BrainstormNew from r/WorldNews: worldnews: Australia news live: NSW records five new locally acquired Covid cases as Qld records one → https://is.gd/nLeH7X03:41
BrainstormNew from r/WorldNews: worldnews: WHO warns no herd immunity in 2021; Moderna says vaccine immunity lasts a year → https://is.gd/Lw5okX03:54
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: The attacks on the US capitol on January 6th, 2021 will have ripple effects for years to come. We’re no longer in the September 11th era. We’re now in the January 6th era. → https://is.gd/MGdH1704:19
jason500[m]god the hype is getting old04:38
jason500[m]bunch of commies04:39
BrainstormNew from r/WorldNews: worldnews: Several gorillas test positive for COVID-19 at California zoo—first in the world → https://is.gd/tlOeF804:44
LjLjason500[m], the bot posted an article that really didn't belong here, but its excuse is it's a bot. what's your excuse? "bunch of commies" is not something i want to read in here tbh04:45
CoronaBot04/r/covid19: The “double eights mask brace” improves the fit and protection of a basic surgical mask amidst COVID-19 pandemic (81 votes) | https://onlinelibrary.wiley.com/doi/epdf/10.1002/emp2.12335 | https://redd.it/kv8z1e04:53
jason500[m]<LjL "jason500, the bot posted an arti"> isn't the entire reason this channel exists is because a bunch of commies released wuhan flu. Seems rather appropriate imo.05:00
jameshandcockand<jason500[m] "isn't the entire reason this cha"> Troll, please go back to reddit05:48
CoronaBot04/r/coronavirus: U.S. Daily Covid Vaccinations Rise by Record 1.25 Million (10333 votes) | https://www.bloomberg.com/news/articles/2021-01-11/u-s-daily-covid-vaccinations-rise-by-record-1-25-million?srnd=prognosis | https://redd.it/kvf7lr05:53
BrainstormNew from r/WorldNews: worldnews: Sinovac's vaccine general efficacy less than 60% in Brazil trial → https://is.gd/zEqxkL05:57
BrainstormNew from r/WorldNews: worldnews: Canada rejects WHO request for immediate vaccine donations to lower-income countries → https://is.gd/bdgsGV06:22
BrainstormUpdates for Belgium: +960 cases (now 665223), +44 deaths (now 20122) since a day ago06:31
BrainstormNew from EurekAlert!: NYUAD study finds fragmented sleep patterns can predict vulnerability to chronic stress: New research from NYU Abu Dhabi's Laboratory of Neural Systems and Behavior for the first time used an animal model to demonstrate how abnormal sleep architecture can be a predictor of stress vulnerability. These important findings have the [... want %more?] → https://is.gd/pUFxk906:34
CoronaBot04/r/covid19: Confirmation of COVID-19 in Gorillas at a California Zoo (86 votes) | https://www.aphis.usda.gov/aphis/newsroom/stakeholder-info/sa_by_date/sa-2021/sa-01/ca-gorillas-sars-cov-2 | https://redd.it/kvj04r06:35
BrainstormNew from The Indian Express: World: Malaysia’s king declares state of emergency to curb spread of COVID-19 → https://is.gd/tjI9xd06:46
BrainstormNew preprint: Factors indicating intention to vaccinate with a COVID-19 vaccine among older U.S. Adults by Janeta Nikolovski et al, made available as preprint on 2021-01-11 at https://medrxiv.org/cgi/content/short/2021.01.10.20248831 [... want %more?]07:21
BrainstormUpdates for C. Valenciana, Spain: +10016 cases (now 174172), +123 deaths (now 3286) since 2 days ago — Extremadura, Spain: +3102 cases (now 46130), +24 deaths (now 1135) since 2 days ago — Castile - Castile La Mancha, Spain: +2958 cases (now 110614), +14 deaths (now 4131) since 2 days ago — Galicia, Spain: +2363 cases (now 67842), +23 deaths (now 1443) since 2 days ago07:39
BrainstormNew from The Indian Express: World: Japan to widen state of emergency beyond Tokyo as coronavirus surges: Media → https://is.gd/8rhvJB07:59
DocScrutinizer05moin08:42
DocScrutinizer05let's hope the recent trend isn't just another artifact in D08:45
BrainstormNew from The Indian Express: World: China expands COVID lockdowns, local political conference delayed → https://is.gd/wuKdjW09:00
BrainstormNew from r/Coronavirus: Daily Discussion Thread | January 12, 2021: The WHO pages contain up-to-date and global information. Please refer to our Wiki for additional information. → https://is.gd/f2ZcSl09:12
zutt%cases sweden09:25
Brainstormzutt: In Sweden, there have been 489471 confirmed cases (4.7% of the population) and 9433 deaths (1.9% of cases) as of 3 days ago. 4.7 million tests were performed (10.4% positive). See https://offloop.net/covid19/?default=Sweden for time series data.09:25
DocScrutinizer05wow, it's amazing how my own words and conclusions - as posted here a few days ago - turn out to be almost identical to this formerly unknown to me FAQ by WHO  https://www.reddit.com/r/Coronavirus/wiki/faq/#wiki_why_are_existing_vaccine_testing_paradigms_useful_for_testing_safety_of_mrna_vaccines.3F09:59
BrainstormNew from Medical Xpress: Going big: US dispensing shots at stadiums and fairgrounds: The U.S. is entering the second month of the biggest vaccination drive in history with a major expansion of the campaign, opening football stadiums, major league ballparks, fairgrounds and convention centers to inoculate a larger and more diverse pool of people. → https://is.gd/jcv9u610:12
DocScrutinizer05AZ applies for EU approval10:20
DocScrutinizer05LOL @ https://onlinelibrary.wiley.com/doi/epdf/10.1002/emp2.1233510:24
DocScrutinizer05double-8 brace10:24
DocScrutinizer05quite nifty10:25
DocScrutinizer05**get proper FFP2/KN95 everybody!**10:26
DocScrutinizer05(or even FFP3)10:26
BrainstormNew from StatNews: Opinion: To make Covid-19 exposure apps work, integrate them with existing popular apps like Facebook: The easiest way to achieve widespread adoption of Covid-19 notification apps would be to integrate them as micro-services within platforms that already have huge market shares, like Facebook, Instagram, Snapchat,… → https://is.gd/w321qU10:50
BrainstormNew from EMA: What's new: PIP: Opinion/decision on a Paediatric investigation plan (PIP): Chimeric anti-disialoganglioside (GD2) monoclonal antibody (ch14.18/CHO) (APN311), decision type: , therapeutic area: , PIP number: P/0094/2014 → https://is.gd/GEUpbR11:02
ubLIX[m]hmm. discussion on preparation for UK variant becoming dominant in US: https://www.nakedcapitalism.com/2021/01/why-new-covid-super-strain-is-a-game-changer.html11:09
ubLIX[m]"A big change is that the U.K. variant appears be somewhere between 40 and 70% more infectious."11:09
ubLIX[m]"To put the U.K. variant in perspective, with its faster spread, we are effectively put back to where we once were without masks — even when we’re now wearing masks!"11:09
ubLIX[m]so.. get proper FFP2/KN95 everybody! 11:11
DocScrutinizer05^^^ +100011:32
DocScrutinizer05you'd think within almost 12 months, they ramped up production capacity for those silly simple things like masks finally, no? So no justification at all anymore for those botch home-knitted masks11:35
DocScrutinizer05here they hand out FFP2 to elderly (60+) now. A 3 per person so far, seems they prepare a second campaign where they send coupons to those eligible to receive them, last year you simply got them in pharmacy showing your ID card for age verification11:37
DocScrutinizer05they still not even recommend to everybody to wear FFP211:37
DocScrutinizer05(in Germany)11:37
DocScrutinizer05it's insane11:38
DocScrutinizer05also schools STILL not closed down for good. And industry/commerce is at 15% home office now, in first wave that were 30% iirc11:38
BrainstormNew from Emma Hodcroft: @firefoxx66: R to @firefoxx66: Getting case numbers down saves #LivesAndLivelihoods, and reduces #SARSCoV2's opportunities to explore situations with unique selection pressures, potentially resulting in mutations expanding that we'd rather not see.Help make my updates more boring: bring cases down!20/20 → https://is.gd/vBYDrq11:39
DocScrutinizer05those morons still didn't learn yet that acting FAST and MASSIVE is of PARAMOUNT importance when fighting a pandemic11:39
DocScrutinizer05the typical statement you hear is >>BUT... there is no EVIDENCE that MY shop is spreading the virus!<<  *headdesk*11:41
DocScrutinizer05if there was you'd go to jail, idiot!11:41
generawe are different, we are it is impossible to do workfromhome11:42
DocScrutinizer05at least B90/Gruene now demands "free FFP2 for everybody"11:49
BrainstormUpdates for Malaysia: +3309 cases (now 141533), +4 deaths (now 559) since 22 hours ago11:50
DocScrutinizer05but no, we got a night curfew, with maximum annoyance factor to people with shifted day/night schedule like me, and virtually no effect at all on reducing contacts11:50
DocScrutinizer05I'm jonestly considering to "rent" a dog just to be allowed to have a walk at night11:52
DocScrutinizer05honestly too11:53
DocScrutinizer05it's starting to feel tough11:55
ubLIX[m]yep11:58
DocScrutinizer05https://youtu.be/DVQ3-Xe_suY12:00
BrainstormNew from Medical Xpress: China places 5 million more under lockdown to stamp out virus cluster: Chinese authorities sealed off a city of almost five million people and imposed strict travel restrictions on several others on Tuesday as they worked to quash a number of COVID-19 clusters near Beijing. → https://is.gd/cPo3J112:16
DocScrutinizer05((walk at night)) nota bene there was *nobody* in the streets at night even before the curfew12:24
DocScrutinizer05I would literally not know any place&time with lower risk - but the rationale for curfew is >>we want to stop private parties this way<< which is ... :-x12:26
DocScrutinizer05no idea why they think private parties need other measures than those they already got to fight disturbance12:38
DocScrutinizer05it's about time to have that curfew reviewed and evaluated by court12:40
BrainstormNew from BMJ: Covid-19: All doctors should be offered first vaccine dose by mid-February, government says: The UK government has promised that every adult in the UK will be offered a covid-19 vaccination by the autumn as it set out plans to rapidly scale up its mass vaccination programme.The UK covid-19... → https://is.gd/tXGkDa12:41
ubLIX[m]i suppose if the curfew has covid-related legal force, then police action to shut down a discovered party becomes an uncomplicated affair, legally speaking12:42
ubLIX[m]existing noise-related legislation might not have provided for instant shut down12:43
ubLIX[m]doesn't help you, but that rationale might have been a factor12:43
ubLIX[m]of course it also makes it easy and faster for police to interdict a party before it happens, if they can just censure any one at all they discover outside after curfew12:45
ubLIX[m]DocScrutinizer05: is there no provision in your local laws for exemption for night shift workers? can you seek documentary support for allowances in this vein? 12:50
BrainstormNew from Emma Hodcroft: @firefoxx66: R to @firefoxx66: PS - For related but slightly-different-angle updates on 501Y.V1 (B.1.1.7) & 501Y.V2 (B.1.351), you should follow @AineToole & keep an eye on her tweets about updated reports!https://twitter.com/AineToole/status/134871592036619468921/20https://is.gd/5xXyQX12:53
DocScrutinizer05ubLIX[m]: I'm not sure I understand "seek documentary support for allowances"12:57
DocScrutinizer05there is a general except for anything work related12:58
DocScrutinizer05I already pondered to set up a paywalled blog "german streets at night" for which I do daily coverage by foto footage12:59
DocScrutinizer05I guess authorities will have a hard time to explain I need to earn money with my job13:00
ubLIX[m]thinking something like.. perhaps locally you are allowed outside for exercises purposes. night shift people perhaps are allowed to exercise outside after curfew otherwise they would be obliged to do nothing except travel immediately home. for those people who are nocturnal, a letter of support from a doctor might protect from police action/fines for taking a walk outside at night13:01
DocScrutinizer05it's the utter nonsense in the rationale of that curfew that irks me - and of course the fact that I may not legally leave home from 21:00 to 5:0013:02
DocScrutinizer05alas no such allowance for anything except commuting for nightshifters13:03
DocScrutinizer05but you may walk your dog as often as you like, any time13:03
ubLIX[m]"Breaking news: Dog theft reaches epidemic proportion in Germany..."13:05
DocScrutinizer05then, government additionally explained - to >>clear up some confusion<< - that it's all about "Aufenthalt im freien". It's tricky to define "aufenthalt"13:06
DocScrutinizer05%tr <de Aufenthalt im freien13:06
BrainstormDocScrutinizer05, German to English: Spending time outside: (MateCat) — Spending time outdoors: (MateCat) — Outdoor living: (MateCat) — Stay outdoors (Google) — Stay in the free (Apertium)13:06
DocScrutinizer05do I "stay" when I walk?13:06
ubLIX[m]perhaps this depends on whether you think spacetime is quantised13:08
DocScrutinizer05sort of13:09
DocScrutinizer05sneaky bastards13:09
DocScrutinizer05one thing's for sure: this regulation is neither fair nor the mildest possible measure to reach the goal, nor appriate/capable to reach the goal at all13:11
DocScrutinizer05appropriate*13:12
DocScrutinizer05those who meet for private parties despite this being explicitly forbidden won't care about any such curfew, worst case they go "hey joe, get more beer, we need to stay at least til 5'o party<<13:14
DocScrutinizer05mission accomplished, contacts *extended* in duration13:15
DocScrutinizer05while I may not have a walk on which I'd not even *see* anybody else13:16
BrainstormNew from The Atlantic: California’s Hospitals Weren’t Ready for This: Everyone’s worst pandemic nightmare is happening in Los Angeles. Intensive care units are overflowing with patients gasping for breath, and there might not be enough ventilators to go around. If a patient has virtually no chance of survival, ambulances have been told not to [... want %more?] → https://is.gd/MxipR313:18
ubLIX[m]recent wired article on test positivity rate in the UK: https://www.wired.co.uk/article/uk-covid-19-test-positivity-rate13:25
ubLIX[m]not sure i'm happy with the conclusion: 'So, what do we do? Vaccinate, says Yates. “The only way out of this is vaccinating enough of the vulnerable people.”'13:25
ubLIX[m]vulnerable people in general are surely the least likely to be superspreaders, so this approach seems like having minimum effect on R0 per dose. prioritising them seems like an all-is-lost last ditch attempt to minimise death toll13:27
ubLIX[m]but i guess with infection rates (recorded, ie less than actual) in places at north of 1 in 30 and climbing, death toll minimisation is the forced strategy here13:29
BrainstormNew from r/WorldNews: worldnews: COVID herd immunity will not happen in 2021, says WHO → https://is.gd/2QgvCs13:30
DocScrutinizer05globally? no way13:30
ubLIX[m]globally? no. just in the UK13:30
DocScrutinizer05re >>herd immunity will not happen<<13:31
DocScrutinizer05>>death toll minimisation is the forced strategy<< ack13:32
ubLIX[m]i'm just imagining that had our epidemic been controlled, prioritising vaccines for superspreaders (healthcare, nursing home staff, young people) could have been a good strategy, saving more people in the long run13:32
ubLIX[m]but because our epidemic is not controlled, we are forced to use a vulnerability-prioritising strategy13:33
ubLIX[m]i guess that's why the UK is going nuts get the vaccine out there as fast as possible13:34
ubLIX[m]*getting13:34
Agyaff[m]I agree, the vaccine is sold as the only way out, which it became but was not in the beginning of this shit shiw13:35
Agyaff[m]In france, the situation is ready to spiral out of control because it is all talk, and no action - worst, the talk is limited to what the economy allows our leaders to talk about. It is fascinating, but I have no family so it's easier to be entertained 🤠13:37
DocScrutinizer05:-S13:38
DocScrutinizer05with the new variants and the average (in)efficiency of NPI that are really getting established, we _may_ reach herd immunity in 2021, alas "the natural way"13:39
DocScrutinizer05have mercy!13:40
BrainstormNew from The Indian Express: World: AstraZeneca applies for EU approval of its vaccine → https://is.gd/TP6eDA13:42
Agyaff[m]Who wants herd immunity for a disease with this kind of symptoms and sequels ? Risk and reward : what reward is mine for taking tht risk ? Going back to work ? What's the incentive here, since when is it worse to pause the activity, reduce it to the bare minimum and let the contagion end itself than asking whole populations to  jump through the fire nd expect for the best ?13:44
Agyaff[m]Will we answer the climate change tht way ?13:44
ubLIX[m]will you be entertained if the answer is yes?13:45
Agyaff[m]Not really, but I realised the futility of my intervention after sending it13:46
Agyaff[m]Sorry13:46
BrainstormUpdates for Germany: +11828 cases (now 1.9 million) since 23 hours ago13:48
ubLIX[m]it's human enough, laughing at the absurd13:49
BrainstormNew from r/WorldNews: worldnews: Coronavirus causes largest U.S. greenhouse gas emissions drop since World War Two: report → https://is.gd/kzLxtl14:07
BrainstormNew from Medical Xpress: Developing new diagnostic approaches to augment COVID-19 biosecurity: Researchers at the Australian National Phenome Centre (ANPC) at Murdoch University have discovered distinct blood signatures present in patients with COVID-19 that could significantly improve COVID-19 testing and long-term monitoring. → https://is.gd/H3aH6I14:44
BrainstormNew from NIH Director's blog: What A Year It Was for Science Advances!: At the close of every year, editors and writers at the journal Science review the progress that’s been made in all fields of science—from anthropology to zoology—to select the biggest advance of the past 12 months. In most cases, this Breakthrough of the Year is as tough to [... want %more?] → https://is.gd/JiDPyL15:09
BrainstormUpdates for Switzerland: +2851 cases (now 487357), +79 deaths (now 8421) since 20 hours ago15:33
BrainstormNew from EMA: What's new: Medicine: Human medicines European public assessment report (EPAR): Comirnaty, COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 21/12/2020, Revision: 1, Status: Authorised → https://is.gd/golaYG15:34
DocScrutinizer05Bavaria mandates FFP2 in public transport and shops - don't tell me rant doesn't help :-D15:39
DocScrutinizer05now **close schools for good**15:40
DocScrutinizer05and make homeoffice mandatory, anybody feeling like they need at-site work done has to file a request to get allowance15:42
DocScrutinizer05and cancel that idiotic pointless night curfew!15:43
DocScrutinizer05ramp up penalties for living room parties instead, I suggest a minimum 1000€ per person and up to 2 years jail for the flat owner15:45
DocScrutinizer05since this is no offense, this is a crime15:46
BrainstormNew from EMA: News and press releases: Cyberattack on EMA - update 4, , 12/01/2021: The ongoing investigation of the cyberattack on EMA revealed that some of the unlawfully accessed documents related to COVID-19 medicines and vaccines... → https://is.gd/ynzqri15:46
BrainstormNew from Medical Xpress: COVID-19 immunity: How long does it last?: Millions of people across the world have been infected with SARS-CoV-2, the virus that causes COVID-19. Countries are also now embarking on massive vaccination campaigns to control the virus and protect their most vulnerable citizens. One of the biggest questions remaining is whether [... want %more?] → https://is.gd/ZEv0Bb15:58
BrainstormNew from Medical Xpress: COVID-19 transmission chains in the UK accurately traced using genomic epidemiology: A team of scientists, led by researchers from the Universities of Oxford and Edinburgh, has analysed the first wave of the COVID-19 outbreak in the UK and produced the most fine-scaled and comprehensive genomic analysis of transmission of any [... want %more?] → https://is.gd/IQzayd16:11
BrainstormUpdates for Netherlands: +3447 cases (now 883988), +67 deaths (now 12495) since 23 hours ago16:35
BrainstormNew from r/Coronavirus: Coronavirus: [CROSSPOST] Science Discussion Series: Preprints, rushed peer review, duplicated efforts, and conflicts of interest led to confusion and misinformation regarding COVID-19. We're experts who analyzed COVID-19 research - let's discuss! → https://is.gd/49lWvZ16:36
BrainstormNew from Ars Technica: Science: Second Dem has COVID after riot, calls for fines against maskless Republicans → https://is.gd/Dq5XmT16:48
IndoAnon>Denmark now counts a positiv COVID test that is 14 days old as a negative test16:53
mjensen[m]How did she get infected? Was she not wearing a mask? I thought they protected you. 16:54
BrainstormNew from ClinicalTrials.gov: (news): Immunologic Responses to Single and Double Doses of SARS-CoV-2 Vaccines in Egyptians → https://is.gd/ZZLiHx17:01
BrainstormUpdates for N. Cyprus: +159 cases (now 1765), +3 deaths (now 10) since 7 days ago — Canada: +7826 cases (now 671115), +147 deaths (now 17113) since 23 hours ago17:07
BrainstormUpdates for UAE: +3243 cases (now 236225), +6 deaths (now 717) since a day ago — Cuba: +487 cases (now 15494), +2 deaths (now 155) since 23 hours ago — Comoros: +6 cases (now 1166), +3 deaths (now 21) since 14 hours ago18:15
BrainstormNew from Medical Xpress: High hopes but slow start: Europe's COVID vaccine drive: Armed with COVID-19 vaccines developed in record time, authorities across Europe are scrambling to quickly innoculate populations against an outbreak that has killed more than 626,000 people on the continent. → https://is.gd/wPJq1l18:15
LjL-Matrixmjensen: that's a common and potentially dangerous misconceptions. Masks are useful to lower the general R, which must be brought down to below 1 in order to make the outbreak slow down instead of getting worse... but at the individual level, just wearing a mask does NOT give you anything like 100% protection, or even 90%. It depends on the mask, but there are also many parameters we just don't know. To get near-100%18:33
LjL-Matrixprotection you'd need a full body suit like they use in high biosafety labs. That's why they tell you that even when wearing a mask, you should respect social distancing etc etc18:33
CoronaBot04/r/coronavirus: Sir David Attenborough receives Covid-19 vaccine (10670 votes) | https://www.bbc.com/news/entertainment-arts-55630861 | https://redd.it/kvrxgv18:34
BrainstormNew from Reddit (test): Tuesday 12 January 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/QSSmwl18:51
BrainstormNew from BMJ: Covid-19: Deaths rise after Christmas in England and Wales: Nearly a third (31.2%) of all deaths in England and Wales in the week ending 1 January involved covid-19, show data from the Office for National Statistics.1Some 11 541 deaths were registered in that... → https://is.gd/jwbviz19:04
BrainstormNew from BBC Health: Covid-19: London's Nightingale hospital taking patients: The facility at the ExCeL Centre also has the capital's first mass vaccination centre on site. → https://is.gd/CXsLLD19:16
BrainstormNew from The Indian Express: World: Second US lawmaker tests positive for COVID-19 after Capitol siege → https://is.gd/VrC56M19:28
BrainstormUpdates for United Kingdom: +33430 cases (now 3.2 million), +875 deaths (now 82835) since 23 hours ago — Italy: +14242 cases (now 2.3 million), +616 deaths (now 79819) since a day ago — Switzerland: +80 deaths (now 8444) since 19 hours ago19:35
BrainstormNew from In The Pipeline: More Things to Do With mRNA: After yesterday’s post on mRNA vaccines and RNA mechanisms, I wanted to highlight a completely non-coronavirus application that has recently appeared in the literature. It’s from BioNTech, the German company who’s been working with Pfizer on one of the two mRNA coronavirus vaccines, of [... want %more?] → https://is.gd/Qtj28u19:41
BrainstormNew from Medical Xpress: English health official warns pandemic entering worst weeks: England's chief medical officer warned Monday that the coming weeks would be the worst of the pandemic for the National Health Service as he appealed to the public to strictly follow guidelines meant to prevent the spread of the disease. → https://is.gd/bRhWK419:53
mjensen[m]<LjL-Matrix "mjensen: that's a common and pot"> I understand that.  I was throwing out a contrarian thought to help spread a little understanding about those that choose not to wear masks (those types tend to deal in absolutes, "either I'm protected or I'm not" They don't tend to accept probability/statistics.)  I think there is a high chance she was exposed elsewhere, but that doesn't fit the political narrative.  (Now19:58
mjensen[m]I'm getting off-topic mentioning politics, so I'll stop)19:58
BrainstormNew from Medical Xpress: New York could run out of vaccine stock by next week's end: mayor: New York City could run out of its COVID-19 vaccine stock "by the end of next week," Mayor Bill de Blasio told journalists Tuesday, calling on the federal government and laboratories to prevent a dearth of doses. → https://is.gd/XKryCy20:18
BrainstormUpdates for Spain: +25438 cases (now 2.1 million), +408 deaths (now 52683) since 22 hours ago20:19
LjLmjensen[m], my policy is that politics is okay here as long as it's related to COVID and we stay civil and don't call people names20:21
LjLbut you don't have to talk about it if you don't want to of course :P20:21
BrainstormUpdates for Netherlands: +5062 cases (now 885614) since 21 hours ago21:15
BrainstormNew from StatNews: Opinion: ICE must provide Covid-19 vaccines to all detained migrants: Our interviews with 50 individuals who had been kept in ICE detention facilities showed how ICE failed to comply with its own Covid-19 pandemic response requirements in at least 22… → https://is.gd/8LNPRd21:32
BrainstormUpdates for France: +293 deaths (now 68353) since 21 hours ago21:40
BrainstormNew from Medical Xpress: New process evaluates patients for elective surgeries following COVID-19: Acknowledging that COVID-19 may be here to stay, Oregon Health & Science University has laid out a series of steps to prepare patients for elective surgery following their illness. → https://is.gd/yf45gw22:09
CoronaBot04/r/covid19: Assessing mandatory stay-at-home and business closure effects on the spread of covid-19 (82 votes) | https://onlinelibrary.wiley.com/doi/epdf/10.1111/eci.13484 | https://redd.it/kvsr0522:12
python476hey22:18
python476LjL: still there man ?22:18
python476hi everybody else 22:18
BrainstormNew from Virological.org: Detection of non-B.1.1.7 Spike ∆69/70 sequences (B.1.375) in the United States:  We currently caution against using TaqPath S dropout as a proxy for B.1.1.7 in the US Gage Moreno 1 , Katarina Braun 2 , Brendan B. Larsen 3 , Tara Alpert 4 , Michael Worobey 3 , Nathan Grubaugh 4 , Thomas Friedrich 2 , David O’Connor 1 , [... want %more?] → https://is.gd/6GBtlE22:21
de-factoRKI COVID-19 Germany 2021-01-12 (relayed rep.?): Weekly Incidence 164.5/100k, Infections +12802 (1933826 total), Fatalities +891 (41577 total), COVID@ICU 5204 (incl 2996 on ventilator)22:31
de-factotitle https://www.destatis.de/EN/Themes/Cross-Section/Corona/Society/population_death.html22:31
de-facto%title22:32
Brainstormde-facto: From www.destatis.de: Number of deaths and excess mortality - Statistisches Bundesamt22:32
de-facto"After average mortality figures were recorded in the first half of October, there has been an above average increase of deaths since the second half of October. At the same time, the number of COVID-19 deaths has been rising again."22:33
LjLAw I missed python47622:35
LjLpython476, i think therefore i am (i think)22:44
BrainstormNew from Medical Xpress: Canada's Ontario province issues stay-at-home order: Canada's Ontario province, the country's most populous and its economic engine, on Tuesday ordered residents to stay home as projections showed the number of COVID-19 cases could soon explode, overwhelming hospitals. → https://is.gd/Dlbaa122:46
de-facto.title https://www.ema.europa.eu/en/news/ema-receives-application-conditional-marketing-authorisation-covid-19-vaccine-astrazeneca22:57
Brainstormde-facto: From www.ema.europa.eu: EMA receives application for conditional marketing authorisation of COVID-19 Vaccine AstraZeneca | European Medicines Agency22:57
de-facto"EMA has received an application for conditional marketing authorisation (CMA) for a COVID-19 vaccine developed by AstraZeneca and Oxford University. The assessment of the vaccine, known as COVID-19 Vaccine AstraZeneca, will proceed under an accelerated timeline."22:57
LjLhow about making it conditional on running a proper phase 3 that is not botched22:58
de-facto"An opinion on the marketing authorisation could be issued by 29 January during the meeting of EMA’s scientific committee for human medicines (CHMP), provided that the data submitted on the quality, safety and efficacy of the vaccine are sufficiently robust and complete and that any additional information required to complete the assessment is promptly submitted."22:58
BrainstormNew from Virological.org: Multiplexed RT-qPCR to screen for SARS-COV-2 B.1.1.7 variants: Preliminary results:  Chantal B.F. Vogels, Tara Alpert, Mallery Breban, Joseph R. Fauver, Nathan D. Grubaugh Yale School of Public Health Contact: nathan.grubaugh@yale.edu Tl;dr - we developed an open-source multiplexed PCR that recreates the TaqPath SGTF [... want %more?] → https://is.gd/lyqwPp22:58
BrainstormNew from Reddit (test): China_Flu: China's Sinovac vaccine has "general efficacy" of 50.4% in Brazil trials, says Butantan → https://is.gd/Sd5TfF23:35
LjLas long as it's above 50.0%!23:37
LjLexcept with 50% you can never reach herd immunity, but hey, i'm sure they have thought of that when they set it as the minimum threshold23:38

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