| LjL | DocScrutinizer05, de-facto, I hide back into the 90s wanna meet me there? I got this in the mail https://pic.infini.fr/BlkpAy2w/2704gkNo | 00:28 |
|---|---|---|
| de-facto | whoa a PSION how neat :)) | 00:36 |
| de-facto | i wish my phone had a keyboard like that one | 00:37 |
| de-facto | thats real tech still, lasting for decades rather than years | 00:38 |
| LjL | de-facto, and a *german* psion! but i have a cunning plan to turn it into english because this model (5mx Pro) doesn't have the OS in ROM but in a CF card, and i can replace it with the english version... if i can find again the site that offers it :P | 01:30 |
| LjL | also i don't have anything to write to CF cards right now but detaaaails | 01:30 |
| LjL | continuing with the german-related offtopic: does this sound right/polite/reasonable? "Nur eine Klarstellung: Ist die Tunerkarte enthalten, wie auf der linken Seite des Bildes gezeigt, oder nur die XQ885 Hauptplatine?" | 01:38 |
| de-facto | are you asking? maybe Nachfrage instead of Klarstellung? | 01:42 |
| de-facto | Klarstellung is more like you make a statement, Nachfrage is you want to ask for clarifying something | 01:42 |
| de-facto | Or maybe also "Anfrage" if its the first inquiry | 01:47 |
| de-facto | LjL, whats a XQ885 thingy? | 01:48 |
| euod[m] | <LjL "DocScrutinizer05, de-facto, I hi"> I have the modern clone of that thing. the keyboard is fantastic. | 01:48 |
| euod[m] | it's tiny but somehow usable. | 01:48 |
| de-facto | i think dTal also talked about having something like that | 01:50 |
| dTal | I have a Cosmo Communicator | 01:51 |
| dTal | "lasting for decades" though, LOL | 01:51 |
| de-facto | ah yeah exactly that one, i just remembered you had something neat with real keyboard :) | 01:53 |
| de-facto | i always wish for something like that when i open Termux in my Android | 01:54 |
| Brainstorm | Updates for Colombia: +21078 cases (now 1.9 million), +377 deaths (now 47868) since a day ago — Nigeria: +1867 cases (now 107345), +8 deaths (now 1413) since a day ago — France: +16111 cases (now 2.9 million) since 23 hours ago — Switzerland: +25 deaths (now 8646) since 9 hours ago | 01:59 |
| LjL | de-facto, ah thanks, yes first inquiry, i'll go with Anfrage then. XQ885 is just the board number for a hifi amplifier/receiver i have, where the radio part is broken | 02:00 |
| LjL | dTal, he didn't mean the Cosmo with lasting for decades :P | 02:01 |
| LjL | although to be fair, the Psions are actually kinda delicate | 02:01 |
| LjL | the hinges break frequently as does the flex cable between the mainboard and the screen | 02:01 |
| dTal | The keyboard is wonderful, the phone and the company suck | 02:01 |
| dTal | but the keyboard is wonderful | 02:01 |
| LjL | i wonder if it's better than a Psion's (aside from looking identical) | 02:01 |
| dTal | (if you're lucky, a lot of people got bad batches, including me) | 02:01 |
| LjL | the Psion keyboard doesn't let you type at full speed, really | 02:02 |
| LjL | when i used it daily to take notes at uni, i got around 2/3 of my "normal" keyboard typing speed (which isn't incredibly high) | 02:02 |
| LjL | dTal, oh :( did you whack them on the head for an exchange? | 02:02 |
| dTal | I have a couple dead Psions I bought on ebay, I think I might prefer the key feel of the Cosmo actually but I've not tried the psions properly | 02:02 |
| LjL | not easy if they're dead :P | 02:03 |
| dTal | LjL: yeah, and they sent me a new keyboard (yay!) which I had to fit myself with no instructions (boo) | 02:03 |
| LjL | dTal, if you want a live Psion, keep an eye for the "Ericsson MC218" on ebay... these days everything is expensive on ebay, but relatively speaking, the MC218 tends to be cheaper than the "real" Psion, but ultimately it's just a rebadged Psion 5mx with minor firmware differences | 02:03 |
| dTal | oh neat tip | 02:04 |
| dTal | interchangeable parrs? | 02:04 |
| LjL | dTal, probably not the screen. or more like, the screen is going to interchange fine i bet, but then the icons will be wrong, because one of the minor differences is that the icons at the bottom of the screen are somewhat different, since the MC218 was meant as a "phone companion" and so it has a terminal emulator or something like that as an icon, which the Psion doesn't | 02:05 |
| LjL | so uh let's say interchangeable keyboards | 02:05 |
| Brainstorm | Updates for Congo: +549 cases (now 7709) since 3 days ago | 02:05 |
| LjL | since if you exchange the mainboard, you're also going to end up with the wrong things on the icons :P | 02:05 |
| LjL | and if you exchange the top it'll say Ericsson instead of Psion or vice versa! | 02:06 |
| LjL | actually | 02:06 |
| LjL | not even the keyboards are fully interchangeable because most MC218s have a layout that isn't UK (QWERTY and everything, but the alt keys have scandinavian characters) | 02:07 |
| LjL | so basically either everything will interchange, or nothing will interchange, depending on how willing you are to accept mismatches :P | 02:07 |
| dTal | I ask because there's a guy on Tindie selling USB to Psion keyboard ribbon adapters | 02:08 |
| dTal | I can vouch that they work | 02:08 |
| dTal | it'd be nice if they worked with this alternate keyboard | 02:09 |
| LjL | dTal: you mean to use a Psion keyboard on a computer, or other day around? | 02:11 |
| dTal | the former | 02:12 |
| LjL | dTal: anyway yeah I bet they'd work, you'd just have to adjust the keymap | 02:12 |
| dTal | I want to build small modern projects with psion keyboards | 02:12 |
| dTal | like a little e-ink laptop | 02:12 |
| LjL | Can't 100% guarantee of course but I'm like 98% | 02:12 |
| LjL | dTal: I think I can send you a Psion keyboard in not great shape... Though not sure how much of a headache Brexit made shipping to/from UK :/ | 02:13 |
| dTal | That's kind of you! But I have one I already diked out of a Psion, and a whole seperate Psion, so I'm okay for now I think | 02:14 |
| LjL | Which, "lol", reminds me I think you offered to send a decent mask once, and I was like nah for now no need, but now it'd probably be much more of a chore | 02:14 |
| dTal | I found a UK website that sells them cheap, and filters too | 02:14 |
| dTal | maybe they'll ship | 02:14 |
| dTal | I definitely think everyone should wear respirators | 02:14 |
| dTal | I'm shocked that demand is still apparently low | 02:15 |
| LjL | Problem is it now transits through Customs, and Customs make thing "disappear" | 02:15 |
| LjL | Before January, shippings from the UK were treated as domestic | 02:15 |
| dTal | I made a post on Hacker News just now that makes the case that personal valved respirators are superior both from a selfish and a societal standpoint | 02:19 |
| dTal | it is controversial | 02:19 |
| de-facto | here they offer a 3-pack of valved FFP3 masks for 10€ in the supermarket/drugstore (Rossmann), i was really surprised they are of decent quality actually | 02:30 |
| de-facto | well ok from the outside they look like decent quality, i have to admit i did not try them yet | 02:34 |
| dTal | Ah, the disposable kind | 02:42 |
| dTal | I recommend the reusable kind | 02:42 |
| dTal | the disposable kind don't have intake valves, so some of your breath still goes through the filter, and thus they get nasty very quickly | 02:43 |
| dTal | not as quickly as valveless ones | 02:43 |
| dTal | but you really don't want to wear one more than a few times | 02:43 |
| de-facto | yeah i have another FFP3 with valve and now noticed they get wet pretty soon with minus degrees outdoors (i always put them on at home for convenience) | 02:44 |
| dTal | https://www.medisave.co.uk/search/?q=gvs+elipse | 02:44 |
| dTal | this website is excellent | 02:45 |
| dTal | (for UK) | 02:45 |
| de-facto | nice one yeah makes sense with valves both on inhale and exhale | 02:46 |
| dTal | also silicone seal is much better | 02:47 |
| dTal | hm, I just had a great idea, I should put nylon over the outside of my mask | 02:47 |
| dTal | protect the filters from the rain, and diffuse the exhaust valve too | 02:50 |
| dTal | also would make it look less scary | 02:50 |
| de-facto | i have something similar but was too shy to wear it yet outdoors because its so big https://www.srsafety.com/uk/products/half-full-face-mask-2359/sr-100-m-l-h01-2012.html | 02:51 |
| de-facto | kind of the opposite airpath, valved inhale in the middle and valved exhale at both sides | 02:52 |
| dTal | oh my that looks very scary | 02:52 |
| de-facto | yeah yours is more compact | 02:53 |
| dTal | I like that yours supports different types of canister in the same mask | 02:54 |
| dTal | the only reason to consider appearance is whether other people will give you trouble over it | 02:54 |
| de-facto | yeah those filters are stackable, so its that black covering, prefilter (fleece), P3 particle filter and maybe chemical filter or such | 02:56 |
| de-facto | but of course they use their own standard to make you buy filters from them | 02:57 |
| dTal | so does everyone | 03:02 |
| dTal | I don't think there's a "standard" filter? | 03:02 |
| de-facto | i think there was some military standard or such | 03:04 |
| Brainstorm | Updates for Germany: +19768 cases (now 2.0 million), +1045 deaths (now 46537) since 21 hours ago | 03:13 |
| LjL | dTal, well, i wanted to make a nice youtube video about the differences between the psion and the ericsson, but my phone and my english have boycotted in numerous ways, last of which the phone shutting off due to dead battery | 03:21 |
| LjL | so another time | 03:21 |
| Brainstorm | Updates for Bolivia: +2573 cases (now 183589), +41 deaths (now 9571) since a day ago — Malawi: +729 cases (now 11223), +6 deaths (now 291) since 12 hours ago — France: +10764 cases (now 2.9 million) since 22 hours ago — Netherlands: +3025 cases (now 905016), +47 deaths (now 12872) since 22 hours ago | 05:36 |
| CoronaBot | 04/r/covid19: CHOP Researchers Find Elevated Biomarker Related to Blood Vessel Damage in All Children with SARS-CoV-2 Regardless of Disease Severity (88 votes) | https://www.chop.edu/news/chop-researchers-find-elevated-biomarker-related-blood-vessel-damage-all-children-sars-cov-2 | https://redd.it/ky9zc5 | 05:51 |
| Brainstorm | Updates for Belgium: +2203 cases (now 675089), +58 deaths (now 20352) since 22 hours ago — Guernsey: +7 cases (now 309) since 8 days ago | 05:55 |
| LjL | ubLIX[m], ↑ (coronabot) | 05:56 |
| de-facto | RKI COVID-19 Germany 2021-01-16: Weekly incidence +139.2/100k, Infections +18678 (2019636 total), Fatalities +980 (45974 total), COVID@ICU 5051 (incl 2923 on ventilator) | 06:39 |
| Brainstorm | Updates for Ancash, Peru: +1240 cases (now 33478), +10 deaths (now 1565) since 2 days ago — Junin, Peru: +1056 cases (now 30395), +18 deaths (now 1014) since 2 days ago — Jalisco, Mexico: +744 cases (now 58910), +65 deaths (now 7004) since a day ago — Piura, Peru: +721 cases (now 44429), +7 deaths (now 2257) since 2 days ago | 07:28 |
| DocScrutinizer05 | moin | 09:15 |
| DocScrutinizer05 | .tr <de Unser Update am Freitag, 15. Januar: ❗️ Das Robert Koch-Institut (RKI) vermeldet für heute erneut keine Fallzahlen für Nürnberg. Unser Gesundheitsamt hat Daten an das Landesamt für Gesundheit und Lebensmittelsicherheit (LGL) übermittelt. Warum sie nicht beim RKI erscheinen, ist leider noch nicht geklärt | 09:52 |
| Brainstorm | DocScrutinizer05, German to English: Our update on Friday, January 15th: ❗️ The Robert Koch Institute (RKI) once again reported no case numbers for Nuremberg for today. Our health department has transmitted data to the State Office for Health and Food Safety (LGL). Unfortunately, it has not yet been clarified why they do not appear at the RKI (MyMemory, Google) [... want %more?] | 09:52 |
| genera | lol | 09:53 |
| Brainstorm | Updates for Indonesia: +14224 cases (now 896642), +283 deaths (now 25767) since 22 hours ago | 10:03 |
| Brainstorm | Updates for Germany: +17655 cases (now 2.0 million) since 21 hours ago | 12:13 |
| CoronaBot | 04/r/coronavirus: Pfizer says it has second doses of COVID-19 shot on hand, expects no U.S. supply problems (10015 votes) | https://www.reuters.com/article/us-health-coronavirus-vaccine-pfizer-idUSKBN29K2LR?taid=600250db947f630001ccbb11&utm_campaign=trueAnthem:+Trending+Content&utm_medium=trueAnthem&utm_source=twitter | https://redd.it/kybc49 | 12:42 |
| Brainstorm | Updates for Malaysia: +4029 cases (now 155095), +8 deaths (now 594) since a day ago — UAE: +3432 cases (now 249808), +7 deaths (now 740) since a day ago — Zambia: +1796 cases (now 36074), +10 deaths (now 537) since 20 hours ago | 12:57 |
| Brainstorm | Updates for Senegal: +342 cases (now 22738), +3 deaths (now 509) since a day ago | 13:40 |
| Brainstorm | Updates for Germany: +17763 cases (now 2.0 million) since 23 hours ago | 14:23 |
| CoronaBot | 04/r/covid19: The lethal triad: SARS-CoV-2 Spike, ACE2 and TMPRSS2. Mutations in host and pathogen may affect the course of pandemic (80 votes) | https://www.biorxiv.org/content/10.1101/2021.01.12.426365v1 | https://redd.it/kxl0b7 | 14:36 |
| DocScrutinizer05 | German cases reported per day (unrelated to original onset date of symptoms or diagnostics) https://i.imgur.com/SKVD5E3.jpg | 16:09 |
| ubLIX[m] | LjL: couple of clicks to reach pdf download of weekly updates: https://legemiddelverket.no/nyheter/covid-19-vaccination-associated-with-deaths-in-elderly-people-who-are-frail | 16:16 |
| mjensen[m] | I haven't read the study yet, but this summary goes against everything that has been said since day-1 of this mess. https://www.newsweek.com/covid-lockdowns-have-no-clear-benefit-vs-other-voluntary-measures-international-study-shows-1561656 | 16:55 |
| CoronaBot | 04/r/covid19: SARS-CoV-2 reinfection in a cohort of 43,000 antibody-positive individuals followed for up to 35 weeks (81 votes) | https://www.medrxiv.org/content/10.1101/2021.01.15.21249731v1 | https://redd.it/kyj0bx | 16:55 |
| Brainstorm | Updates for Portugal: +10947 cases (now 539416), +166 deaths (now 8709) since a day ago — Netherlands: +5534 cases (now 909433), +96 deaths (now 12966) since 23 hours ago | 17:17 |
| Brainstorm | Updates for United Kingdom: +75349 cases (now 3.4 million), +2099 deaths (now 88590) since 23 hours ago — Canada: +6914 cases (now 698763), +179 deaths (now 17780) since 23 hours ago | 17:36 |
| Brainstorm | Updates for Ecuador: +3942 cases (now 230808), +43 deaths (now 14316) since 22 hours ago — Italy: +16310 cases (now 2.4 million), +475 deaths (now 81800) since 23 hours ago — Switzerland: +32 deaths (now 8673) since 23 hours ago | 18:13 |
| Jigsy | %cases UK | 18:16 |
| Brainstorm | Jigsy: In United Kingdom, there have been 3.4 million confirmed cases (5.1% of the population) and 88590 deaths (2.6% of cases) as of 40 minutes ago. 63.1 million tests were performed (5.3% positive). See https://offloop.net/covid19/?default=United%20Kingdom for time series data. | 18:16 |
| Arsanerit | %cases Micronesia | 18:34 |
| Brainstorm | Arsanerit: In Micronesia, there have been 1 confirmed cases (0.0% of the population) and 0 deaths (0.0% of cases) as of 6 days ago. See https://offloop.net/covid19/?default=Micronesia for time series data. | 18:34 |
| de-facto | %cases 2021 | 18:41 |
| Brainstorm | de-facto: Sorry, 2021 not found. Either there aren't cases, or it's under a different name. | 18:41 |
| de-facto | lol optimist... | 18:41 |
| Jigsy | Micronesia living up to it's name. | 19:15 |
| DocScrutinizer05 | >>Among 43,044 anti-SARS-CoV-2 positive persons who were followed for a median of 16.3 weeks (range: 0-34.6), 314 individuals (0.7%) had at least one PCR positive swab ≥14 days after the first-positive antibody test. Of these individuals, 129 (41.1%) had supporting epidemiological evidence for reinfectio<< "SARS-CoV-2 reinfection in a cohort of 43,000..." https://www.medrxiv.org/content/10.1101/2021.01.15.21249731v1 | 19:39 |
| DocScrutinizer05 | <1%, sounds plausible and not surprising | 19:40 |
| DocScrutinizer05 | actualy this is a quite good result | 19:41 |
| Jigsy | 3>New Brazil Covid variant probably already in UK | 19:43 |
| Jigsy | Another one!? | 19:43 |
| DocScrutinizer05 | or... depending on number of infections in a comparable antibody-negative reference group, a meaningless or very bad result | 19:43 |
| DocScrutinizer05 | Jigsy: I seem to recall a >>Brazil variant is not a "Variant Of Concern"<< | 19:44 |
| DocScrutinizer05 | damn matrix bridge | 19:44 |
| DocScrutinizer05 | or maybe not | 19:45 |
| DocScrutinizer05 | is there sort of automatic color mode in mIRC v7.63 ? | 19:46 |
| LjL | no it's something Jigsy (or Jigsy's client) does | 19:46 |
| LjL | honestly i don't know if the Brazil variant is concerning or not, i sometimes read it's not, sometimes that it may be the end of the known universe | 19:46 |
| Jigsy | It's me doing /gt <text>. | 19:46 |
| Jigsy | Hmm... | 19:47 |
| LjL | if you can avoid colors that would be better. the channel "allows" colors because if i set +c to disallow them, then the bot can no longer use bold and italics either, and those are kinda useful | 19:47 |
| LjL | would be nice if there were separate chanmodes for colors and bold/italics/underline | 19:47 |
| Jigsy | Oh, right, I forgot I was asked not to use colors. | 19:48 |
| de-facto | imho those E484K variants need to be investigated further, especially since the re-outbreaks in Manaus et al | 19:57 |
| DocScrutinizer05 | LjL: even better would be a per user(group) setting for colors | 19:59 |
| LjL | DocScrutinizer05, well to be fair clients could have options to strip colors, it would probably be easiest at the client level | 19:59 |
| DocScrutinizer05 | alternative: bot sends /mode -c; >infotext with formating>; /mode +c | 20:00 |
| de-facto | https://nextstrain.org/ncov/global?c=gt-S_484 | 20:00 |
| DocScrutinizer05 | I know, a PITA | 20:00 |
| de-facto | .title https://virological.org/t/genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-manaus-preliminary-findings/586 | 20:01 |
| Brainstorm | de-facto: From virological.org: Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings - nCoV-2019 Genomic Epidemiology - Virological | 20:01 |
| de-facto | "The new lineage, named P.1 (descendent of B.1.1.28), contains a unique constellation of lineage defining mutations, including several mutations of known biological importance such as E484K, K417T, and N501Y." | 20:02 |
| de-facto | "Importantly, the P.1 lineage was identified in 42% (13 out of 31) RT-PCR positive samples collected between 15 to 23 December, but it was absent in 26 publicly available genome surveillance samples collected in Manaus between March to November 2020." | 20:02 |
| LjL | de-facto, is that Brazil, or? | 20:02 |
| LjL | oh, yeah Manaus | 20:02 |
| de-facto | "The recent emergence of variants with multiple shared mutations in spike raises concern about convergent evolution to a new phenotype, potentially associated with an increase in transmissibility or propensity for re-infection of individuals." | 20:02 |
| de-facto | yes Brazil | 20:03 |
| DocScrutinizer05 | yeah, convergence | 20:04 |
| de-facto | "The lineage distribution for the newly-generated December genomes from Manaus was as follows: 65% B.1.1.28 lineage, 16% B.1.161, 11% B.1.1.33, 5% B.1.149, and 3% B.1.150." | 20:04 |
| DocScrutinizer05 | E484K and N501Y seem to be | 20:04 |
| de-facto | The 24 new B.1.1.28 sequences from Manaus download here: https://github.com/CADDE-CENTRE/Novel-SARS-CoV-2-P1-Lineage-in-Brazil | 20:06 |
| DocScrutinizer05 | the mRNA vaccines should get adjusted to those, immediately | 20:06 |
| DocScrutinizer05 | it's pretty obvious that we WILL see them eventually | 20:06 |
| de-facto | .title https://science.sciencemag.org/content/371/6526/288 | 20:08 |
| Brainstorm | de-facto: From science.sciencemag.org: Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic | Science | 20:08 |
| DocScrutinizer05 | and aiui a E484K and N501Y adapted mRNA would still be of sufficient efficiency to the "old" variants | 20:08 |
| de-facto | "We use a convenience sample of blood donors to show that by June 2020, 1 month after the epidemic peak in Manaus, 44% of the population had detectable immunoglobulin G (IgG) antibodies. Correcting for cases without a detectable antibody response and for antibody waning, we estimate a 66% attack rate in June, rising to 76% in October." | 20:08 |
| de-facto | bye bye herd immunity by natural recovery | 20:08 |
| DocScrutinizer05 | hm? | 20:09 |
| DocScrutinizer05 | you say they had a 76% immuno-competence when running into a second wave? | 20:11 |
| de-facto | yes | 20:12 |
| LjL | fwiw i read the UK was looking at stopping the Brazil variant from coming, so at least they considered it potentially worse than their own | 20:12 |
| DocScrutinizer05 | :-S | 20:14 |
| de-facto | seems they are using so much oxygen in the hospitals of Manaus that they currently have problems with the supply chain (at least thats in the media one day ago or such) | 20:15 |
| de-facto | does not sound so good | 20:15 |
| de-facto | no wonder new variants with escaping potential emerge in such a population | 20:17 |
| Brainstorm | Updates for Lebanon: +5872 cases (now 249158), +41 deaths (now 1866) since a day ago — Comoros: +149 cases (now 1577), +3 deaths (now 41) since 19 hours ago — Germany: +17503 cases (now 2.0 million), +859 deaths (now 46592) since 23 hours ago | 20:17 |
| genera | do they have any special animals, like mink or bats? | 20:17 |
| de-facto | thats exactly the reason why i think we need to do everything to come as close as possible to having neutralizing immunity in the majority of population, hence do the full 2 dose schemes in order to guarantee the highest amount of antibodies as possible | 20:18 |
| de-facto | good question genera i dont know about the economy of Manaus | 20:18 |
| de-facto | what about mice and rats, dogs and cats? | 20:19 |
| de-facto | well dogs probably dont really play a role id assume, their immunity is pretty good | 20:20 |
| de-facto | at least to the previous variants | 20:20 |
| genera | you said "no wonder .." but i missed the part before? | 20:20 |
| LjL | mjensen[m], i have read, well, at least the abstract of the study you linked from newsweek, i.e. https://onlinelibrary.wiley.com/doi/10.1111/eci.13484 - i think these correlation studies are very tricky to make. some countries behaved similarly despite having different interventions, often countries near one another, while other countries behaved very differently, with or without similar interventions. in general, it's problematic to compare with East | 20:20 |
| LjL | Asian countries, because, for some reason which i won't even try to guess right now, their incidence has been much lower... but i think the reason is way too uncertain to use these countries and correlate to their lack of lockdowns. they also look at Sweden: overall, when you compare for example Sweden and Italy in terms of cases and deaths per capita, they are similar in the end, but... if you look at the cumulative curve, there is a definite flattening | 20:20 |
| LjL | in Italy after the lockdown happened, while there is no such thing in Sweden. *yes*, the end result is more or less the same, but i'd like to stress that the good old Imperial College paper from March 2020 more or less predicted this, i.e. that lockdowns would "flatten the curve" for a while but then there would be a big resurgence: the idea was to delay the resurgence until we had time to up our medical interventions | 20:20 |
| DocScrutinizer05 | >>mice and rats, dogs and cats?<< seems cats can't spread. Dogs not even mentioned | 20:21 |
| LjL | genera, i think he meant, no wonder that in a population where the virus is so aggressively infecting everybody (for whatever reason), variants emerge...? | 20:21 |
| LjL | DocScrutinizer05, cats can spread to other cats. was there evidence they can't spread to humans? | 20:22 |
| LjL | dogs can get it, weakly, but failed to spread it, last i heard | 20:22 |
| DocScrutinizer05 | it's what I heard in TV today where they checked all sorts of animals in a high-sec lab somewhere in germany | 20:22 |
| de-facto | Löffler Inst? | 20:23 |
| LjL | i hope they publish a study | 20:23 |
| DocScrutinizer05 | cows replicate poorly so they are no problem | 20:23 |
| DocScrutinizer05 | cats can't transfer to humans | 20:23 |
| DocScrutinizer05 | they didn't even mention dogs | 20:23 |
| LjL | yeah i have seen some papers on cows, chicken and other animals we eat, they seemed not to be a problem | 20:23 |
| DocScrutinizer05 | de-facto: quite possible | 20:24 |
| LjL | DocScrutinizer05, i wonder how did they establish cats can't transfer to humans? among themselves, they just try and see if other cats get infected; but for humans, wouldn't it require a (somewhat unethical) challenge study where a human gets put next to an infected cat for a while? | 20:24 |
| LjL | maybe they tested human cells? | 20:25 |
| DocScrutinizer05 | I think zhey infer that from symptoms aka where and how the virus shows | 20:25 |
| DocScrutinizer05 | in cows they checked for virus concentration in blood and concluded it'S unlikely cows could spread | 20:26 |
| LjL | hmm, i'm skeptical of that sort of inference, like at first it was taken for granted most companion/domesticated animals weren't getting infected simply because we hadn't spotted any | 20:26 |
| LjL | %links animals | 20:26 |
| Brainstorm | LjL, https://vac-lshtm.shinyapps.io/ncov_tracker/ (nCoV Tracker) has a map with an (animated) timeline — https://covid19-dash.herokuapp.com/ (Global Kaggle Data's dashboard), another animated dashboard — https://healthmap.org/covid-19/ (Healthmap), a third animated dashboard [... want %more?] | 20:26 |
| LjL | lol | 20:26 |
| LjL | it catches "animated" because i'm using a stemmer :\ | 20:26 |
| DocScrutinizer05 | hehehe | 20:26 |
| LjL | or... maybe i can keep the stemmer but prioritize search results obtained without the stemmer | 20:27 |
| LjL | anyway, i had some articles about animals | 20:27 |
| LjL | %links cats | 20:27 |
| Brainstorm | LjL, mortality rates are https://rpubs.com/tonynick/covidinfoecd (higher than regular seasonal flus) and if they are allowed to spike, they may https://www.thenewatlantis.com/imgLib/20200414_CovidweeklydeathsNYv3.jpg (dwarf death figures from all causes) (graphs from https://www.thenewatlantis.com/publications/not-like-the-flu-not-like-car-crashes-not-like (The New Atlantis)) [... want %more?] | 20:27 |
| LjL | oh come on | 20:27 |
| LjL | %links pigs | 20:27 |
| Brainstorm | LjL, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164390/ (Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2) finds that the virus replicates poorly in dogs, pigs, chickens, and ducks, but ferrets and cats are permissive to infection, including airborne for cats; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164390/ (SARS-CoV-2 in [... want %more?] | 20:27 |
| LjL | finally | 20:27 |
| DocScrutinizer05 | we know ferrets and minks can transfer to human | 20:29 |
| de-facto | i dont think its ping pong from animals though (yet its a possibility), i think its mutations selected by the fading immunity in the currently circulating variants | 20:29 |
| DocScrutinizer05 | they said in TV cats can't. No idea on what they based this notion | 20:29 |
| de-facto | also in SA there probably are some people that may not have the most aggressive immune capabilities (e.g. due to HIV infection etc) | 20:30 |
| DocScrutinizer05 | de-facto: in Brazil et al? definitely. Mutation rate is roughly proportional to incidences and illness duration | 20:30 |
| de-facto | we really would need to have a study of E484K vs non-E484K variants in cell cultures under (non-neutralizing) concentrations of blood serum of a representative selection of people that seroconverted due to Wuhan-spike vaccination | 20:33 |
| de-facto | to estimate the magnitude of immuno-evasion capability by that variant with the current generation of vaccination | 20:34 |
| de-facto | why would it? | 20:34 |
| DocScrutinizer05 | you may dream? | 20:35 |
| LjL | DocScrutinizer05, i think i added that paper before the Danish mink situation happened | 20:35 |
| de-facto | why isomaltin? | 20:35 |
| LjL | also i'm trying to make %links smarter now | 20:35 |
| DocScrutinizer05 | I don't even know if isomaltin is a thing | 20:35 |
| DocScrutinizer05 | thus $++ | 20:36 |
| de-facto | %links broadest | 20:36 |
| Brainstorm | de-facto, Sorry, nothing found. Try with broader keywords | 20:36 |
| de-facto | %papers E484k | 20:37 |
| Brainstorm | de-facto, 3 papers: Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment by Mary Hongying Cheng et al, made available as preprint on 2021-01-11 at https://biorxiv.org/cgi/content/short/2021.01.10.426143 [... want %more?] | 20:37 |
| de-facto | %more | 20:37 |
| Brainstorm | de-facto, [...] Genomic characterization of a novel SARS-CoV-2 lineage from Rio de Janeiro, Brazil by Carolina M Voloch et al, made available as preprint on 2020-12-26 at https://medrxiv.org/cgi/content/short/2020.12.23.20248598 [...] → https://paste.ee/p/rN485 | 20:37 |
| DocScrutinizer05 | honestly I don't mind which of the 9999 E numbers for food additives will turn out to be the miracle virus killer. I just hope we will find such a thing. Easy to produce and to administer, known to do no harm, highly effective | 20:39 |
| DocScrutinizer05 | there been Carageen, didn't hear of that again | 20:40 |
| de-facto | .title https://www.biorxiv.org/content/10.1101/2020.12.28.424451v1 | 20:40 |
| Brainstorm | de-facto: From www.biorxiv.org: SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma | bioRxiv | 20:40 |
| DocScrutinizer05 | %papers carageen | 20:41 |
| Brainstorm | DocScrutinizer05: An error occurred while searching. | 20:41 |
| DocScrutinizer05 | %papers carag | 20:42 |
| Brainstorm | DocScrutinizer05: An error occurred while searching. | 20:42 |
| DocScrutinizer05 | %papers ageen | 20:42 |
| Brainstorm | DocScrutinizer05: An error occurred while searching. | 20:42 |
| DocScrutinizer05 | %papers carrageenan | 20:43 |
| Brainstorm | DocScrutinizer05, 8 papers: Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: re-analysis of randomized trial data by Harri Hemilä et al, made available as preprint on 2020-11-15 at [u'https://doi.org/10.21203/rs.3.rs-108775/v1', u'https://www.researchsquare.com/article/rs-108775/v1.pdf'] [... want %more?] | 20:43 |
| DocScrutinizer05 | u'https:// ? | 20:44 |
| DocScrutinizer05 | ;-) I don't care UTF-8 | 20:45 |
| DocScrutinizer05 | LjL: ^^^ | 20:45 |
| LjL | DocScrutinizer05, oh yeah i remember that one, it was annoying because sometimes it's a single link (then it gets displayed properly), some other times it's a list | 20:58 |
| LjL | %paper carrageenan | 21:01 |
| Brainstorm | LjL, 8 papers: Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: re-analysis of randomized trial data by Harri Hemilä et al, made available as preprint on 2020-11-15 at https://doi.org/10.21203/rs.3.rs-108775/v1 [... want %more?] | 21:01 |
| LjL | hopefully this works with all of them. it will only show the first link, if there's a list | 21:01 |
| LjL | in this case the doi.org link redirects right away to researchsquare.com anyway | 21:01 |
| LjL | i might have reasonably fixed %links too | 21:02 |
| LjL | %links animals | 21:04 |
| Brainstorm | LjL, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164390/ (Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2) finds that the virus replicates poorly in dogs, pigs, chickens, and ducks, but ferrets and cats are permissive to infection, including airborne for cats; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164390/ (SARS-CoV-2 in [... want %more?] | 21:04 |
| LjL | it still links to things stemmed from "anim", but later in %more | 21:04 |
| LjL | side effect is links will be listed in reverse order from the way they are on the website, but who cares | 21:05 |
| Haley[m] | %cases France | 21:05 |
| Brainstorm | Haley[m]: In France, there have been 2.9 million confirmed cases (4.3% of the population) and 69949 deaths (2.4% of cases) as of 13 hours ago. 39.5 million tests were performed (7.3% positive). See https://offloop.net/covid19/?default=France for time series data. | 21:05 |
| Brainstorm | Updates for France: +14337 cases (now 2.9 million), +277 deaths (now 70061) since 23 hours ago — Mozambique: +858 cases (now 25862), +18 deaths (now 234) since 22 hours ago | 21:59 |
| DocScrutinizer05 | vaccine overprovisioning (in doses, so prolly /2) per country: Canada 9, USA 7, EU 5, India 2 | 22:30 |
| DocScrutinizer05 | source: https://programm.ard.de/TV/tagesschau24/Startseite/?sendung=287213967248049 | 22:32 |
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