Brainstorm | New from r/WorldNews: worldnews: India Covid: Thousands gather for dung-throwing festival as cases top 200k in a day → https://is.gd/ORUDGv | 00:05 |
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de-facto | .title https://www.fnlondon.com/articles/double-mutant-covid-19-variant-detected-in-uk-20210416 | 00:35 |
Brainstorm | de-facto: From www.fnlondon.com: ‘Double mutant’ Covid-19 variant detected in UK - Financial News | 00:35 |
de-facto | .title https://www.gov.uk/government/news/confirmed-cases-of-covid-19-variants-identified-in-uk | 00:36 |
Brainstorm | de-facto: From www.gov.uk: Confirmed cases of COVID-19 variants identified in UK - GOV.UK | 00:36 |
Brainstorm | New from The Lancet (Online): [Correspondence] COVID-19: time for ethical reflection?: Kayvan Bozorgmehr1 highlighted the need to bring ethical reflections into the debate about guidelines on managing the COVID-19 pandemic.1,2 Indeed, Bozorgmehr poses questions about the medical and moral pertinence of the public health policy implemented in Germany [... want %more?] → https://is.gd/unMKfR | 00:36 |
de-facto | "The variant, first detected in India, includes a number of mutations including E484Q, L452R, and P681R. PHE has identified 77 cases of this variant in the UK and all appropriate public health interventions will be undertaken, including enhanced contact tracing." | 00:36 |
de-facto | LOVELY. | 00:36 |
de-facto | how nice for the VoCs that they STILL can travel globally and freely conveniently via low latency passenger airtravel. | 00:37 |
de-facto | .title https://www.theguardian.com/world/2021/apr/15/covid-variant-first-detected-india-found-uk | 00:38 |
Brainstorm | de-facto: From www.theguardian.com: Covid variant first detected in India is found in the UK | Coronavirus | The Guardian | 00:38 |
de-facto | btw the "double mutant" VoC that probably is responsible for ~60% of cases in Maharashtra/India case explosion in is called B.1.617 | 00:40 |
de-facto | LjL did you know it already reached Europe now? see above articles about the successful import in UK | 00:41 |
LjL | yay | 00:42 |
de-facto | https://outbreak.info/situation-reports?pango=B.1.617 | 00:44 |
de-facto | i really really dont understand why passenger airtravel is not completely illegal by now | 00:45 |
LjL | i know | 00:46 |
LjL | i see it's already in Germany too and not just the UK, grand | 00:48 |
LjL | what's the deal with the mutants in Canada? the US is warning against travel in Canada now (as if Canada let Americans enter), and Ontario is out of control or something | 00:48 |
LjL | but i'm not sure what they have aside from just B.1.1.7 | 00:49 |
de-facto | looking at the recent case explosion in India and the claim its at least 60% B.1.617 makes me wonder what properties those mutations E484Q, L452R, and P681R have | 00:51 |
LjL | it makes me hope that it will be QUICKLY tested against existing vaccines | 00:51 |
de-facto | for E484Q one might assume correlation of properties with the already known E484K in B.1.351 and P.1 | 00:51 |
LjL | because i'm pretty sure it's going to be "the next big thing" | 00:51 |
de-facto | hence probably also has some evasive potential against current gen vaccines | 00:52 |
LjL | if you see populations as "computing power" for the virus, India is just a huge one | 00:52 |
de-facto | not sure about the other two, do they already know what L452R means for the virus? | 00:52 |
LjL | dunno | 00:52 |
de-facto | LjL, yes damn thats very true, india got a BIG population | 00:53 |
LjL | a big population, with the virus not under control (unlike china), crammed living conditions, generally bad healthcare | 00:53 |
LjL | i fear Brazil is going to sound good in comparison | 00:53 |
LjL | and Brazil, while big, doesn't have as many people | 00:53 |
de-facto | and yeah India probably just cant contain it in some areas, because people need to do their daily work in order to sustain their income, they cant afford to just stay indoors for a year etc | 00:54 |
LjL | even assuming "keep 2 meters from other people" is useful for anything (i doubt it), that's just something you physically can't do in some indian cities | 00:55 |
LjL | also, from what i've heard before, while private hospitals have been compelled by the government to treat COVID patients for free, many just refuse, and some states don't enforce this | 00:56 |
LjL | and there isn't really any public healthcare | 00:56 |
LjL | i guess the only good thing they have on their side is a big pharmaceutical industry | 00:56 |
de-facto | i wonder how India could prevent cases from exploding before and what this VoC now changed, i.e. is it that much more reproductive to raise R over anything achievable with containment before so cases just go and explode exponentially with R~1.4 or such? | 00:57 |
LjL | i've always seen India as a timebomb with COVID and so far i was just surprised at the fact it had stayed relatively "calm" | 00:58 |
de-facto | yeah and india got a young population afaik | 00:58 |
LjL | which is to say, i don't think they could have done much to contain it | 00:58 |
de-facto | India got a median age of 28.7 years | 00:59 |
LjL | man | 01:00 |
de-facto | quite young in comparison to Germany 47.8 years or Italy 46.5 years | 01:00 |
de-facto | https://en.wikipedia.org/wiki/List_of_countries_by_median_age | 01:00 |
LjL | Italy has already lost more than a year of life expectancy with COVID according to whatever i remember reading | 01:01 |
LjL | but then somewhere else it says that Europe roughly lost 10 years with the 1918 flu | 01:01 |
LjL | i'm surprised Germany is older than Italy | 01:01 |
LjL | but it's pretty much the only country to be except Japan and some countries that don't really matter :P | 01:02 |
LjL | not that it's a badge of honor... | 01:02 |
LjL | de-facto, prepare to get mad: "India is not on the red list so there is no requirement for hotel quarantine. Instead returning travellers are required to take two COVID tests and quarantine at home for 10 days." (UK) | 01:04 |
de-facto | https://covariants.org/variants/S.L452R | 01:05 |
de-facto | https://covariants.org/variants/S.P681 | 01:05 |
de-facto | https://covariants.org/variants/S.E484 | 01:05 |
de-facto | yeah https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Risikogebiete_neu.html | 01:07 |
de-facto | 10 days Quarantine for travelers from India, after 5 days a negative test can abort quarantine | 01:08 |
LjL | it's not even listed as a "Virusvarianten-Gebieten" | 01:08 |
LjL | clearly european bureaucracy is useless to stay on top of things | 01:08 |
de-facto | combined with the fact that MEDIAN incubation time is ~5.2 days (half of cases less, other half more) its absolutely FUTILE to allow aborting quarantine after 5 days with a test | 01:09 |
de-facto | probably they even allow quicktest, as idiotic as they are | 01:09 |
de-facto | hence: FUCKING make airtravel COMPLETELY illegal. NOW! | 01:10 |
LjL | i can't do it | 01:10 |
LjL | you can keep saying it forever, i still can't do it | 01:10 |
de-facto | industry is WAY too stupid to implement proper hygiene, as it seems government is too as they are nothing more than prostitutes to the lobbyists nowadays | 01:10 |
de-facto | we will see variants spreading globally over and over again | 01:11 |
de-facto | because we still tolerate global traveling and we still cant coordinate a global strategy to address COVID | 01:12 |
de-facto | even Germany cant do it internally, government completely failed to contain it | 01:12 |
de-facto | btw quarantine means people get told to "please stay at home and avoid contacts" | 01:15 |
de-facto | its not even controlled in any way | 01:15 |
de-facto | of course that leads to people not caring and do whatever they like | 01:16 |
de-facto | who would notice if they quickly go to the supermarket? etc | 01:17 |
de-facto | or travelers from Mallorca, they do a quicktest prior to entering the airplane and thats it | 01:17 |
LjL | well, Pfizer will be happy | 01:18 |
de-facto | any cheapo rapid antigen test, not even certified or anything | 01:19 |
Chimeroo | They're saying you need a third shot now, no? | 01:19 |
LjL | Chimeroo, yes, but that's not really big news despite many people seemingly being surprised by it | 01:20 |
LjL | pretty sure i'm not surprised and de-facto is not surprised | 01:20 |
LjL | we'll need a yearly shot for the foreseeable rest of our lives | 01:20 |
LjL | the difference is between it being mainly a booster to immunity and perhaps to cover the odd variant | 01:20 |
LjL | and it being a never-ending chase *after* new variants | 01:20 |
Chimeroo | I've heard that is difficult to get shots for many people since there shortages, and time conflicts because people work etc, specifically my friends from Washington | 01:20 |
Chimeroo | I'm not sure if that's a unique case though | 01:20 |
de-facto | well if its for the rest of our lives remains to be seen, but when governments and people continue to act as ignorant and reckless as in the year one after the pandemic chances that we ever will control it are low indeed | 01:21 |
LjL | time conflicts because people work? seriously? | 01:22 |
LjL | in the current situation, *that* is a concern? | 01:22 |
de-facto | here in Germany i have absolutely no chance to get any vaccine until the fall or begin of the next winter or such | 01:22 |
de-facto | and i am very angry about that | 01:23 |
Chimeroo | the irony is that the guy is a streamer, and he works from home, so he complains his stream sch conflicts with giving the vaccine | 01:23 |
de-facto | the vaccine will be any approved platform probably with a two year old spike protein signature by then | 01:24 |
de-facto | not sure if its even effective for the variants that will be circulating by then | 01:24 |
LjL | Chimeroo, okay, well, since i share the same situation as de-facto, tell your friend to get fucked, with all my respect | 01:24 |
Chimeroo | lol | 01:24 |
de-facto | its not that allowing global travel is none of my business, it directly affects the level of protection i can expect from the vaccine that may be offered to me one bright day in the future | 01:26 |
Chimeroo | do you have a union? | 01:27 |
de-facto | same goes for tolerating high incidence over extended periods of time, it basically means allowing for breeding new evasive mutations | 01:27 |
de-facto | https://en.wikipedia.org/wiki/Kumbh_Mela#COVID-19 | 01:41 |
de-facto | https://timesofindia.indiatimes.com/india/covid-19-at-maha-kumbh-mela-top-seer-dies-niranjani-akhada-announces-exithighlights/articleshow/82095684.cms | 01:42 |
LjL | i know, although i think that's probably too recent to be the cause of the spike | 01:43 |
de-facto | yeah but it would not exactly reduce contacts would it? | 01:45 |
* LjL shrugs | 01:46 | |
LjL | try convincing religious persons of things | 01:46 |
Brainstorm | New from r/WorldNews: worldnews: Sputnik V: How Russia's COVID vaccine is dividing Europe → https://is.gd/E3ybBF | 01:47 |
de-facto | from the guardian article i linked above https://www.theguardian.com/world/2021/apr/15/covid-variant-first-detected-india-found-uk | 01:53 |
de-facto | "Prof Paul Hunter, professor in medicine at the University of East Anglia, said the arrival of the India variant was potentially worrying." | 01:53 |
de-facto | "“These two escape mutations working together could be a lot more problematic than the South African and Brazilian variants who have only got one escape mutation,” he said. “It might be even less controlled by vaccine than the Brazilian and South African variants.”" | 01:54 |
de-facto | "However, more research is needed to explore the role of these mutations and the impact they might have." | 01:54 |
de-facto | https://twitter.com/chrischirp/status/1382733894756220934 | 01:56 |
de-facto | "Prof. Christina Pagel" | 01:57 |
de-facto | Guardian said she told | 01:58 |
de-facto | "“We don’t know yet whether it can escape existing vaccines but it has several concerning mutations,” she told the Guardian. “It is ridiculous that India is not on the travel red list yet – or many other countries for that matter – when India is seeing 200,000 new cases every day at the moment.”" | 01:58 |
LjL | :\ | 01:59 |
LjL | it really is ridiculous | 01:59 |
de-facto | https://www.youtube.com/watch?v=TxllewZvELE "Why are Covid cases in India soaring? - BBC Newsnight" | 02:02 |
de-facto | damn. this is very bad. | 02:06 |
Brainstorm | New from r/WorldNews: worldnews: Vietnam calls for faster vaccine rollout before shots expire → https://is.gd/1lHp2b | 02:07 |
de-facto | https://www.youtube.com/watch?v=LR-o-a2xrow "One bed, two patients: India’s hospitals overwhelmed by rising Covid-19 infections" | 02:13 |
de-facto | at least they have a 2 week lockdown in Maharashtra/India from 2021-04-14th it seems | 02:14 |
de-facto | before India was exporting vaccines, now they are urging for importing from any source possible | 02:16 |
LjL | assuming they work | 02:17 |
de-facto | yeah | 02:17 |
de-facto | not only have we not nearly enough vaccine production capacity, also we have outdated signatures | 02:18 |
de-facto | meanwhile in Brazil | 02:20 |
de-facto | https://www.youtube.com/watch?v=KtK9VnGVeHs "Why are so many babies dying of Covid-19 in Brazil? - BBC News" | 02:20 |
de-facto | "Despite the overwhelming evidence that Covid-19 rarely kills young children, in Brazil 1,300 babies have died from the virus. " | 02:20 |
de-facto | https://www.bbc.com/news/world-latin-america-56696907 "Why are so many babies dying of Covid-19 in Brazil?" | 02:25 |
LjL | didn't the MIS "alarm bell" ring several months ago but then somehow got muted | 02:39 |
de-facto | yes i think so | 02:40 |
de-facto | people dont like to hear bad news, hence they keep repeating "children are not affected" and "children are not transmitting it" bla bla | 02:41 |
LjL | yeah, my pessimism has served me well the past year | 02:41 |
de-facto | unfortunately, meaning that wishful thinking is fatal in a pandemic | 02:41 |
de-facto | here they were opening schools without mandatory masks for the children etc | 02:42 |
de-facto | i know that first hand from friends, they refused to allow their children to participate in school until they at least started implementing some hygiene there | 02:42 |
de-facto | afaik now they at least have to wear masks | 02:43 |
de-facto | if testing ever will be made mandatory, we will see | 02:43 |
de-facto | imho we need a MUCH more aggressive containment strategy, worldwide | 02:48 |
LjL | <CoronaBot> /r/coronavirus: Stanford begins testing Pfizer COVID-19 vaccine on children as young as 2 (1001 votes) | 02:49 |
LjL | <CoronaBot> https://www.latimes.com/california/story/2021-04-15/stanford-begins-testing-pfizer-covid-19-vaccine-on-children-as-young-as-2 | https://redd.it/mrzy1h | 02:49 |
de-facto | that is very good that they start to investigate that now, we need to also have some immunization strategy for children as they simple will not distance in schools etc | 02:51 |
de-facto | "The trial will start by testing a 10-microgram dose of the vaccine, then progress to doses of 20 and 30 micrograms if it safe to do so, according to Pfizer. For comparison, people 16 and older receive two 30-microgram doses 21 days apart." | 02:52 |
de-facto | "“The goal is really to find the right dose for little kids and make sure they tolerate the dose, don’t develop high fevers or any adverse events from these vaccines,” Maldonado said. “Once we get a good dose that seems to work well, we will then move into phases two and three.”" | 02:52 |
de-facto | "The study will include 144 volunteers in phase one, and up to 4,500 in phases two and three, according to Pfizer." | 02:53 |
de-facto | https://www.latimes.com/science/story/2021-03-16/moderna-begins-testing-covid-19-vaccine-young-children | 02:54 |
de-facto | "In the first stage of the trial, researchers will test various doses of vaccine to see which works best. Study participants between the ages of 2 and 11 will receive either 50 or 100 micrograms per dose, while those ages 6 months to just under 24 months will get 25, 50 or 100 micrograms per dose." | 02:55 |
Brainstorm | New from Reddit (test): Covid2019: Mexican-made COVID-19 vaccine could be ready this year → https://is.gd/s1bXgp | 03:09 |
CoronaBot | /r/covid19: Why US coronavirus tracking can’t keep up with concerning variants (81 votes) | https://www.nature.com/articles/d41586-021-00908-0 | https://redd.it/ms90a7 | 04:49 |
Brainstorm | New from Reddit (test): Europe vs America: C19 response: I’m totally lost on this subject. I have friends and family around various parts of the US (I’m American but live in Europe) who have shared with me how where they live, there hasn’t been any type of lockdown scenario since maybe late spring of 2020 or so. → https://is.gd/LFTzoC | 05:52 |
LjL | what a moron | 05:55 |
Brainstorm | New from r/WorldNews: worldnews: Peru’s Vizcarra banned from public office over vaccine scandal: Congress approved former president’s temporary ban from public office by 86 votes in favour and zero against. → https://is.gd/7FOIoy | 06:32 |
Brainstorm | New from The Indian Express (Health): Fashion: Designer Manish Malhotra tests positive for COVID 19 → https://is.gd/zluSdH | 06:53 |
Brainstorm | New from r/WorldNews: worldnews: India Record 234k Fresh Covid Cases 1,341 Deaths In 24 Hours → https://is.gd/RruomJ | 07:24 |
CoronaBot | /r/coronavirus: Angela Merkel gets her AstraZeneca COVID vaccine shot (10023 votes) | https://www.dw.com/en/angelamerkel-gets-her-astrazeneca-covid-vaccine-shot/a-57222191 | https://redd.it/ms5442 | 07:44 |
CoronaBot | /r/covid19: Mask adherence and rate of COVID-19 across the United States (80 votes) | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0249891 | https://redd.it/msc9vc | 08:45 |
Brainstorm | New from r/Coronavirus: Daily Discussion Thread | April 17, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/dxd8yl | 09:07 |
Brainstorm | New from r/WorldNews: worldnews: Global Covid death toll nears 3m as India sees another daily record rise in cases → https://is.gd/c2kKFR | 09:27 |
Brainstorm | New from r/WorldNews: worldnews: A Cancer Vaccine Is In Development By COVID-19 Vaccine Maker, Using The Same Tech → https://is.gd/ccltkr | 09:57 |
Brainstorm | New from r/WorldNews: worldnews: China’s Sinovac COVID-19 vaccine 67% effective in preventing symptomatic infection → https://is.gd/0Snu1Z | 11:18 |
Brainstorm | New from The Indian Express: World: Worldwide Covid-19 death toll tops a staggering 3 million → https://is.gd/Wp6lrt | 11:29 |
Brainstorm | New from Medical Xpress: COVID lockdown empties Delhi streets amid deadly surge: New Delhi led major cities across India into a weekend lockdown Saturday as the country confronts a fierce new coronavirus wave, with more than 230,000 fresh daily cases and families clamouring for drugs and hospital beds. → https://is.gd/VH6VRq | 12:10 |
Brainstorm | New from The Indian Express: World: Who’s paying for Europe’s COVID-related debts? → https://is.gd/CETPxa | 12:41 |
CoronaBot | /r/covid19: Down but far from out: The durability of SARS-CoV-2 immunity after asymptomatic infection (82 votes) | https://rupress.org/jem/article-pdf/218/5/e20210359/1413673/jem_20210359.pdf | https://redd.it/msig1r | 12:47 |
Brainstorm | New from Il Sole 24 Ore: Niente pensione ai medici “senior” che vaccinano: «Per fare le iniezioni ci rimettiamo»: Una norma introdotta a metà marzo sospende il trattamento previdenziale durante i mesi di svolgimento dell’attività di vaccinazione retribuita con contratti a prestazione → https://is.gd/lvpJ6p | 12:52 |
Brainstorm | New from r/WorldNews: worldnews: Dogs can sniff out positive coronavirus samples with 96% accuracy → https://is.gd/BkZ0Ku | 13:53 |
Brainstorm | New from The Indian Express (Health): Life-style: ‘I got to play the most important role of my career during pandemic’: Sonu Sood → https://is.gd/po963U | 14:03 |
Brainstorm | New from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 16 aprile 2021: Ulteriori misure urgenti in materia di contenimento e gestionedell'emergenza epidemiologica da COVID-19. (21A02379) → https://is.gd/SXOgFW | 15:15 |
Brainstorm | New from This Week In Virology: TWiV 744: COVID-19 clinical update #58 with Dr. Daniel Griffin: In COVID-19 clinical update #58, Daniel Griffin provides the latest update on the J&J vaccine pause, healthcare worker deaths, children and COVID, physical inactivity associated with higher risk, using monoclonal antibodies for prophylaxis, and shows us how [... want %more?] → https://is.gd/5CUcd3 | 16:29 |
Brainstorm | New from r/WorldNews: worldnews: Worldwide COVID-19 death toll tops a staggering 3 million → https://is.gd/trRplj | 16:49 |
Gregory | Status social | 17:40 |
CoronaBot | /r/covid19: Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination (81 votes) | https://www.nejm.org/doi/full/10.1056/NEJMoa2105385 | https://redd.it/ms8qhj | 18:37 |
LjL | de-facto, ↑ British study out apparently, on some 20 patients, onlt 60% femae | 18:41 |
LjL | female | 18:41 |
LjL | "Among the 23 patients included in this study, the median age was 46 years (range, 21 to 77), with 16 patients (70%) younger than 50 years" | 18:43 |
LjL | three patients above 60 | 18:43 |
LjL | the ones above 60 though, none of them had CVST | 18:45 |
LjL | ubLIX[m], ping | 18:45 |
LjL | pretty long times between vaccination and hospital admission | 18:46 |
Brainstorm | New from Reddit (test): Saturday 17 April 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/tuWDg5 | 18:47 |
Brainstorm | New from r/WorldNews: worldnews: Royal fans defy Covid restrictions, flock to Windsor to say farewell → https://is.gd/iUvNEZ | 18:57 |
Brainstorm | New from r/WorldNews: worldnews: UK delivers more than 600,000 vaccines in 24 hours → https://is.gd/dfphTp | 19:28 |
AntonioGulino[m] | Italia: Ieri sono state somministrate 347.279 dosi di vaccino. Si tratta del nuovo record per un singolo giorno. | 19:36 |
AntonioGulino[m] | https://www.ansa.it/sito/notizie/cronaca/2021/04/17/vaccini-record-di-347.279-dosi-ieri_906e71d9-5f22-4635-bbf3-b98d49bcd204.html | 19:36 |
LjL | not entirely sure why everyone seems to be getting AZ though | 20:17 |
LjL | https://lab24.ilsole24ore.com/numeri-vaccini-italia-mondo/# | 20:18 |
LjL | the majority are getting Pfizer, who are this majority? | 20:18 |
LjL | i thought healthcare operators and people 80+ were already pretty much all done | 20:18 |
LjL | so who's getting all the Pfizer | 20:18 |
Brainstorm | New from r/WorldNews: worldnews: Spreading faster, hitting harder – why young Brazilians are dying of Covid | Coronavirus → https://is.gd/7bTmnK | 20:19 |
Brainstorm | New from NPR: Global COVID-19 Deaths Top 3 Million: The largest number of deaths have come in the United States, Brazil, Mexico, India and the United Kingdom. The global pandemic death toll reached 1 million in September 2020 and 2 million in January. → https://is.gd/gAyfSW | 21:10 |
Arsanerit | Moderna? Jansen? Curevac? | 21:26 |
LjL | ? | 21:31 |
Arsanerit | never mind | 21:32 |
LjL | i don't know what you're asking but Moderna is not very available in Europe, Janssen is stopped as a precaution and has never been used here so far, and Curevac is still in trial | 21:36 |
diofantoz | ah great, a double mutation variant | 21:38 |
diofantoz | ... | 21:38 |
Arsanerit | When are we getting enough vaccines we can use in the European Union? | 21:41 |
de-facto | LjL, interesting, so pretty much the same as Greinacher published before | 21:48 |
de-facto | yet i still wonder about what causes that PF4 to occur | 21:51 |
Brainstorm | New from r/WorldNews: worldnews: COVID-19 pushes India’s middle class toward poverty- Second wave is threatening the dreams of millions more looking for a better life. → https://is.gd/DxVG2d | 22:01 |
CoronaBot | /r/covid19: The story behind COVID-19 vaccines (80 votes) | https://science.sciencemag.org/content/372/6538/109.full | https://redd.it/mstax0 | 22:27 |
kreyren | https://invidious.snopyta.org/watch?v=NLBvglVMLEc | 23:24 |
kreyren | apparently today it's 3M+ dead due to covid | 23:24 |
Brainstorm | New from r/WorldNews: worldnews: AstraZeneca: a second Canadian had a blood clot after receiving the vaccine → https://is.gd/XkZfNO | 23:32 |
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